Patents Assigned to University of South Bohemia
  • Yeast Strain And Screening Method For Identifying Inhibitors Of The Expression Of The Hexose Transporter Genes By A Positive Phenotype
    Publication number: 20090035755
    Abstract: The present invention provides screening procedures for identifying inhibitors of components of regulatory networks by a positive phenotype and modified yeast cell lines suitable for said screening. The screening procedures are especially suited to screen for substances that re-sensitize resistant pathogenic microorganisms or tumor cells by suspending the expression of resistance-relevant genes. The invention further provides methods for constructing said cell lines and their use in screening systems.
    Type: Application
    Filed: November 25, 2005
    Publication date: February 5, 2009
    Applicant: University of South Bohemia
    Inventors: Milan Höfer, Jost Ludwig, Petra Schwanewilm, Juilus Subik