Patents Assigned to University of Southern California, USC Stevens Center for Innovation
  • Publication number: 20160234473
    Abstract: A method for stereo image rectification includes receiving a plurality of images and determining a matrix for performing rectification on the plurality of images based on a first cost function and a second cost function. The first cost function may be associated with a distance of a corresponding pair of points from among the plurality of images. The second cost function may be associated with distortion in a converted image.
    Type: Application
    Filed: February 4, 2016
    Publication date: August 11, 2016
    Applicant: University of Southern California USC Stevens Center for Innovation
    Inventors: OUK CHOI, Hyunsuk KO, C.C. Jay KUO, Han Suk SHIM
  • Patent number: 8110361
    Abstract: Particular aspects confirm the existence of a CpG island methylator phenotype (CIMP) in colorectal cancer, and provide novel validated DNA methylation markers associated with CIMP. Additional aspects provide novel methods and compositions for: determining CIMP status in colorectal cancers, determining the relationship between CIMP status and other molecular features of the cancers (e.g., BRAF mutation, KRAS mutation and MSI status); determining the relationship between CIMP status and other variables (e.g., age, sex, tumor location, family history, race, country of origin, tumor characteristics (including, tumor type, tumor grade, invasive margin characteristics, lymphocyte infiltration characteristics, direct spread, lymph node spread, venous spread and type of residual adjacent polyp, if present)); and determining, between subgroups defined by CIMP status and BRAF mutations, effects of selected risk factors (e.g.
    Type: Grant
    Filed: May 2, 2006
    Date of Patent: February 7, 2012
    Assignee: University of Southern California USC Stevens Center for Innovation
    Inventors: Peter W. Laird, Kimberly D. Siegmund, Mihaela Campan, Daniel J. Weisenberger, Tiffany I. Long
  • Patent number: 7553627
    Abstract: There is disclosed an improved high-throughput and quantitative process for determining methylation patterns in genomic DNA samples based on amplifying modified nucleic acid, and detecting methylated nucleic acid based on amplification-dependent displacement of specifically annealed hybridization probes. Specifically, the inventive process provides for treating genomic DNA samples with sodium bisulfite to create methylation-dependent sequence differences, followed by detection with fluorescence-based quantitative PCR techniques. The process is particularly well suited for the rapid analysis of a large number of nucleic acid samples, such as those from collections of tumor tissues.
    Type: Grant
    Filed: September 8, 2006
    Date of Patent: June 30, 2009
    Assignee: University of Southern California, USC Stevens Center for Innovation
    Inventors: Peter W. Laird, Cindy A. Carroll, Kathleen D. Danenberg