Patents Assigned to University of Sunderland
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Publication number: 20220387342Abstract: A transdermal patch is provided, wherein the patch comprises a cross-linked poly(ethylene oxide) hydrogel loaded with naltrexone, or a pharmaceutically acceptable salt or solvate thereof, and an occlusive adhesive tape. The poly(ethylene oxide) hydrogel has a crosslink density of at least 4.5×10?4 mol cm?3 and not more than 16×10?4 mol cm?3. Also provided are methods for preparing naltrexone-loaded cross-linked poly(ethylene oxide) hydrogels, transdermal patches for use as a medicament, for example in the treatment of a specified condition with LDN therapy.Type: ApplicationFiled: October 22, 2020Publication date: December 8, 2022Applicant: University of SunderlandInventors: Kalliopi Dodou, Philippa Dooley
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Patent number: 9856230Abstract: The present subject matter relates generally to compounds having the formula (I): wherein each of X, Y, R1, R2, R3, R4, and n are as defined herein. Compounds of formula (I) may act as inhibitors of the thioredoxin reductase enzyme system. The subject matter also relates to use, formulation and preparation of the compounds. The compounds may be useful in the treatment of inflammatory and oxidative diseases and conditions. The compounds may also provide useful anti-proliferative and anti-apoptotic effects.Type: GrantFiled: December 20, 2013Date of Patent: January 2, 2018Assignee: UNIVERSITY OF SUNDERLANDInventors: Adam Todd, Rosaleen Joy Anderson, David Antony Phillip Small, Paul William Groundwater, Matthew Richard Benton
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Patent number: 8530599Abstract: A method of preparing hydrophobic silica particles includes the step of reacting together in a single step a mixture of silane ether monomers and organically modified silane ether monomers with a hydrolyzing agent. The method also includes producing hydrophobic silica microparticles and nanoparticles that can include dyes and/or magnetizable components. The silica nanoparticles can be used in the detection, visualization and/or analysis of latent fingerprints.Type: GrantFiled: September 26, 2011Date of Patent: September 10, 2013Assignee: University of SunderlandInventor: Frederick John Rowell
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Patent number: 8258173Abstract: The present subject matter relates generally to antioxidant compounds having the formula (I): wherein each of R1, R2, R3, and R4 are as defined below. These compounds are potentially useful as, for example, antioxidants.Type: GrantFiled: November 19, 2007Date of Patent: September 4, 2012Assignee: University of SunderlandInventors: Rosaleen Joy Anderson, Paul William Groundwater, David Antony Philip Small, Yu Gong
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Patent number: 8026328Abstract: A method of preparing hydrophobic silica particles includes the step of reacting together in a single step a mixture of silane ether monomers and organically modified silane ether monomers with a hydrolyzing agent. The method also includes producing hydrophobic silica microparticles and nanoparticles that can include dyes and/or magnetizable components. The silica nanoparticles can be used in the detection, visualization and/or analysis of latent fingerprints.Type: GrantFiled: August 9, 2006Date of Patent: September 27, 2011Assignee: University of SunderlandInventor: Frederick John Rowell
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Patent number: 7923682Abstract: The present invention is directed to a method for determining the presence of a residue on or within a fingerprint using matrix-assisted mass spectrometric techniques. The matrix-assisted mass spectrometric technique can be selected from Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Time-Of-Flight Mass Spectrometry (MALDI-TOF-MS) and/or Surface Assisted Laser Desorption/Ionisation Time-Of-Flight Mass Spectrometry (SALDI-TOF-MS).Type: GrantFiled: August 9, 2006Date of Patent: April 12, 2011Assignee: University of SunderlandInventors: Frederick John Rowell, Brendan John Theaker
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Publication number: 20100245061Abstract: A method and apparatus for providing information to an operator of a device, such as a currency dispensing machine, is disclosed. The apparatus includes a surface, for example a keypad, that is touched by an operator. The keys of the keypad vibrate in response to an input signal. By reference to a reference location, a centrally located key, the vibration indicates to the operator a direction. Variation in the intensity or duration of vibration pulses is also used to indicate distance or can be used to provide other information.Type: ApplicationFiled: April 17, 2008Publication date: September 30, 2010Applicant: UNIVERSITY OF SUNDERLANDInventors: Brendan Michael Cassidy, Gilbert Cocokton
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Patent number: 7781225Abstract: There is described an affinity-chromatography assay system comprising with an immobilized component containing a bio-reagent and a flowable component containing a complimentary bio-reagent characterized in that the immobilized component is supported on a dip strip or planar surface and the flowable component is adapted to flow down the dip strip of high density. There is also described a method of conducting an affinity-chromatography assay which comprises the use of such an assay system.Type: GrantFiled: January 20, 2004Date of Patent: August 24, 2010Assignee: University of SunderlandInventor: Frederick John Rowell
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Publication number: 20070196656Abstract: A method of preparing hydrophobic silica particles includes the step of reacting together in a single step a mixture of silane ether monomers and organically modified silane ether monomers with a hydrolyzing agent. The method also includes producing hydrophobic silica microparticles and nanoparticles that can include dyes and/or magnetizable components. The silica nanoparticles can be used in the detection, visualization and/or analysis of latent fingerprints.Type: ApplicationFiled: August 9, 2006Publication date: August 23, 2007Applicant: UNIVERSITY OF SUNDERLANDInventor: Frederick Rowell
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Publication number: 20070187587Abstract: The present invention is directed to a method for determining the presence of a residue on or within a fingerprint using matrix-assisted mass spectrometric techniques. The matrix-assisted mass spectrometric technique can be selected from Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Time-Of-Flight Mass Spectrometry (MALDI-TOF-MS) and/or Surface Assisted Laser Desorption/Ionisation Time-Of-Flight Mass Spectrometry (SALDI-TOF-MS).Type: ApplicationFiled: August 9, 2006Publication date: August 16, 2007Applicant: UNIVERSITY OF SUNDERLANDInventors: Frederick Rowell, Brendan Theaker