Patents Assigned to University of Sunderland
  • Patent number: 12060315
    Abstract: Methods are provided for the synthesis of a compound of formula (X). R2 is selected from —H, —C1-C4-alkyl, —C2-C4-alkenyl and C1-C4-aryl; R3 is selected from —C(O)H and —C(O)C1-C4-alkyl; and A is a pharmaceutically acceptable anion (e.g. a halide). Also provided are intermediate compounds formed during the synthesis.
    Type: Grant
    Filed: February 14, 2020
    Date of Patent: August 13, 2024
    Assignee: University of Sunderland
    Inventors: Rosaleen Joy Anderson, Lisa Frost, Neil Barnwell, Matthew Levick, Ivan Hales, Michael Dunn
  • Publication number: 20220387342
    Abstract: A transdermal patch is provided, wherein the patch comprises a cross-linked poly(ethylene oxide) hydrogel loaded with naltrexone, or a pharmaceutically acceptable salt or solvate thereof, and an occlusive adhesive tape. The poly(ethylene oxide) hydrogel has a crosslink density of at least 4.5×10?4 mol cm?3 and not more than 16×10?4 mol cm?3. Also provided are methods for preparing naltrexone-loaded cross-linked poly(ethylene oxide) hydrogels, transdermal patches for use as a medicament, for example in the treatment of a specified condition with LDN therapy.
    Type: Application
    Filed: October 22, 2020
    Publication date: December 8, 2022
    Applicant: University of Sunderland
    Inventors: Kalliopi Dodou, Philippa Dooley
  • Patent number: 8530599
    Abstract: A method of preparing hydrophobic silica particles includes the step of reacting together in a single step a mixture of silane ether monomers and organically modified silane ether monomers with a hydrolyzing agent. The method also includes producing hydrophobic silica microparticles and nanoparticles that can include dyes and/or magnetizable components. The silica nanoparticles can be used in the detection, visualization and/or analysis of latent fingerprints.
    Type: Grant
    Filed: September 26, 2011
    Date of Patent: September 10, 2013
    Assignee: University of Sunderland
    Inventor: Frederick John Rowell
  • Patent number: 8258173
    Abstract: The present subject matter relates generally to antioxidant compounds having the formula (I): wherein each of R1, R2, R3, and R4 are as defined below. These compounds are potentially useful as, for example, antioxidants.
    Type: Grant
    Filed: November 19, 2007
    Date of Patent: September 4, 2012
    Assignee: University of Sunderland
    Inventors: Rosaleen Joy Anderson, Paul William Groundwater, David Antony Philip Small, Yu Gong
  • Patent number: 8026328
    Abstract: A method of preparing hydrophobic silica particles includes the step of reacting together in a single step a mixture of silane ether monomers and organically modified silane ether monomers with a hydrolyzing agent. The method also includes producing hydrophobic silica microparticles and nanoparticles that can include dyes and/or magnetizable components. The silica nanoparticles can be used in the detection, visualization and/or analysis of latent fingerprints.
    Type: Grant
    Filed: August 9, 2006
    Date of Patent: September 27, 2011
    Assignee: University of Sunderland
    Inventor: Frederick John Rowell
  • Patent number: 7923682
    Abstract: The present invention is directed to a method for determining the presence of a residue on or within a fingerprint using matrix-assisted mass spectrometric techniques. The matrix-assisted mass spectrometric technique can be selected from Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Time-Of-Flight Mass Spectrometry (MALDI-TOF-MS) and/or Surface Assisted Laser Desorption/Ionisation Time-Of-Flight Mass Spectrometry (SALDI-TOF-MS).
    Type: Grant
    Filed: August 9, 2006
    Date of Patent: April 12, 2011
    Assignee: University of Sunderland
    Inventors: Frederick John Rowell, Brendan John Theaker
  • Patent number: 7781225
    Abstract: There is described an affinity-chromatography assay system comprising with an immobilized component containing a bio-reagent and a flowable component containing a complimentary bio-reagent characterized in that the immobilized component is supported on a dip strip or planar surface and the flowable component is adapted to flow down the dip strip of high density. There is also described a method of conducting an affinity-chromatography assay which comprises the use of such an assay system.
    Type: Grant
    Filed: January 20, 2004
    Date of Patent: August 24, 2010
    Assignee: University of Sunderland
    Inventor: Frederick John Rowell