Patents Assigned to University of Sunderland
  • Enzyme inhibitors
    Patent number: 9856230
    Abstract: The present subject matter relates generally to compounds having the formula (I): wherein each of X, Y, R1, R2, R3, R4, and n are as defined herein. Compounds of formula (I) may act as inhibitors of the thioredoxin reductase enzyme system. The subject matter also relates to use, formulation and preparation of the compounds. The compounds may be useful in the treatment of inflammatory and oxidative diseases and conditions. The compounds may also provide useful anti-proliferative and anti-apoptotic effects.
    Type: Grant
    Filed: December 20, 2013
    Date of Patent: January 2, 2018
    Assignee: UNIVERSITY OF SUNDERLAND
    Inventors: Adam Todd, Rosaleen Joy Anderson, David Antony Phillip Small, Paul William Groundwater, Matthew Richard Benton
  • Hydrophobic silica particles and methods of making same
    Patent number: 8530599
    Abstract: A method of preparing hydrophobic silica particles includes the step of reacting together in a single step a mixture of silane ether monomers and organically modified silane ether monomers with a hydrolyzing agent. The method also includes producing hydrophobic silica microparticles and nanoparticles that can include dyes and/or magnetizable components. The silica nanoparticles can be used in the detection, visualization and/or analysis of latent fingerprints.
    Type: Grant
    Filed: September 26, 2011
    Date of Patent: September 10, 2013
    Assignee: University of Sunderland
    Inventor: Frederick John Rowell
  • Melatonin derivatives and their use as antioxidants
    Patent number: 8258173
    Abstract: The present subject matter relates generally to antioxidant compounds having the formula (I): wherein each of R1, R2, R3, and R4 are as defined below. These compounds are potentially useful as, for example, antioxidants.
    Type: Grant
    Filed: November 19, 2007
    Date of Patent: September 4, 2012
    Assignee: University of Sunderland
    Inventors: Rosaleen Joy Anderson, Paul William Groundwater, David Antony Philip Small, Yu Gong
  • Hydrophobic silica particles and methods of making same
    Patent number: 8026328
    Abstract: A method of preparing hydrophobic silica particles includes the step of reacting together in a single step a mixture of silane ether monomers and organically modified silane ether monomers with a hydrolyzing agent. The method also includes producing hydrophobic silica microparticles and nanoparticles that can include dyes and/or magnetizable components. The silica nanoparticles can be used in the detection, visualization and/or analysis of latent fingerprints.
    Type: Grant
    Filed: August 9, 2006
    Date of Patent: September 27, 2011
    Assignee: University of Sunderland
    Inventor: Frederick John Rowell
  • Fingerprint analysis using mass spectrometry
    Patent number: 7923682
    Abstract: The present invention is directed to a method for determining the presence of a residue on or within a fingerprint using matrix-assisted mass spectrometric techniques. The matrix-assisted mass spectrometric technique can be selected from Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Time-Of-Flight Mass Spectrometry (MALDI-TOF-MS) and/or Surface Assisted Laser Desorption/Ionisation Time-Of-Flight Mass Spectrometry (SALDI-TOF-MS).
    Type: Grant
    Filed: August 9, 2006
    Date of Patent: April 12, 2011
    Assignee: University of Sunderland
    Inventors: Frederick John Rowell, Brendan John Theaker
  • APPARATUS AND METHOD FOR PROVIDING INFORMATION TO A VISUALLY AND/OR HEARING IMPAIRED OPERATOR
    Publication number: 20100245061
    Abstract: A method and apparatus for providing information to an operator of a device, such as a currency dispensing machine, is disclosed. The apparatus includes a surface, for example a keypad, that is touched by an operator. The keys of the keypad vibrate in response to an input signal. By reference to a reference location, a centrally located key, the vibration indicates to the operator a direction. Variation in the intensity or duration of vibration pulses is also used to indicate distance or can be used to provide other information.
    Type: Application
    Filed: April 17, 2008
    Publication date: September 30, 2010
    Applicant: UNIVERSITY OF SUNDERLAND
    Inventors: Brendan Michael Cassidy, Gilbert Cocokton
  • Surface layer affinity-chromatography
    Patent number: 7781225
    Abstract: There is described an affinity-chromatography assay system comprising with an immobilized component containing a bio-reagent and a flowable component containing a complimentary bio-reagent characterized in that the immobilized component is supported on a dip strip or planar surface and the flowable component is adapted to flow down the dip strip of high density. There is also described a method of conducting an affinity-chromatography assay which comprises the use of such an assay system.
    Type: Grant
    Filed: January 20, 2004
    Date of Patent: August 24, 2010
    Assignee: University of Sunderland
    Inventor: Frederick John Rowell
  • Hydrophobic silica particles and methods of making same
    Publication number: 20070196656
    Abstract: A method of preparing hydrophobic silica particles includes the step of reacting together in a single step a mixture of silane ether monomers and organically modified silane ether monomers with a hydrolyzing agent. The method also includes producing hydrophobic silica microparticles and nanoparticles that can include dyes and/or magnetizable components. The silica nanoparticles can be used in the detection, visualization and/or analysis of latent fingerprints.
    Type: Application
    Filed: August 9, 2006
    Publication date: August 23, 2007
    Applicant: UNIVERSITY OF SUNDERLAND
    Inventor: Frederick Rowell
  • Fingerprint analysis using mass spectrometry
    Publication number: 20070187587
    Abstract: The present invention is directed to a method for determining the presence of a residue on or within a fingerprint using matrix-assisted mass spectrometric techniques. The matrix-assisted mass spectrometric technique can be selected from Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Time-Of-Flight Mass Spectrometry (MALDI-TOF-MS) and/or Surface Assisted Laser Desorption/Ionisation Time-Of-Flight Mass Spectrometry (SALDI-TOF-MS).
    Type: Application
    Filed: August 9, 2006
    Publication date: August 16, 2007
    Applicant: UNIVERSITY OF SUNDERLAND
    Inventors: Frederick Rowell, Brendan Theaker