Abstract: A single-stage transmitter for wireless power transfer is provided. The transmitter includes a rectifier stage and an inverter stage sharing a first phase leg. The rectifier stage further includes a rectifying leg including two diodes connected in series, and a boost inductor coupling the first phase leg and the rectifying leg to an input port. The inverter stage further includes a second phase leg. Each phase leg includes two switches connected in series. The first and second phase legs are coupled to an output port. A bus capacitor is coupled across the first phase, second phase, and rectifying legs. A controller is programmed to determine first and second parameters, based on an output power at the output port, to simultaneously control the rectifier stage and the inverter stage to maintain constant bus voltage and achieve high power factor and low total harmonic distortion at the input port.

Abstract: Example embodiments of a radiation detection system including a detector is described. The detector can include a scintillator, a sensor, and a light source. The radiation detection system can further include a controller programmed to control the light source to expose the scintillator to a light to saturate traps in the scintillator. In some embodiments, the detector can further include a second light source, and the controller is programmed to control the second light source to expose the scintillator to a second light to detrap afterglow traps in the scintillator.

Abstract: This invention relates to the treatment of breast cancer in a subject, for example a female subject.

Abstract: A method includes performing by a processor: receiving a plurality of power system phase angle measurements over a time interval from a plurality of phasor measurement units (PMUs) in a power system, generating a phase angle curve over the time interval based on the plurality of power system phase angle measurements, and detecting a sustained oscillation event in a power signal generated by the power system based on an envelope of the phase angle curve.

Abstract: Described herein is a wireless charging system including switched capacitor (SC) rectifiers with output regulation. The load for the receiver on mobile devices using wireless charging is a battery. Regulation is needed for battery charging applications, e.g. constant voltage charging, constant current charging, and pulsed charging. For this purpose, the wireless power transfer (WPT) receiver can possess some “intelligence” to monitor the output voltage/current, adjust the behavior of the electronic circuitries and achieve a closed-loop control. Because a multilevel switched-capacitor (MSC) rectifier has output control ability, this can allow the MSC rectifier to directly charge the battery without an additional DC/DC charger on-board the device.

Abstract: A solid multiphase polymer blend material comprising: (i) a polyphenolic substance having a molecular weight of at least 500 g/mol; and (ii) a polyester having a molecular weight of at least 500 g/mol; wherein at least a portion of the polyphenolic substance is covalently bonded directly or through a linking moiety to the polyester. Methods for producing the blend material are also described, e.g., homogeneously melt blending a mixture comprising components (i) and (ii) under conditions resulting in covalent attachment of at least a portion of the polyphenolic substance directly or through a linking moiety to the polyester. Methods for producing objects made of the blend material by melt extrusion are also described.

Abstract: A method and apparatus for constructing one of a neuroscience-inspired artificial neural network and a neural network array comprises one of a neuroscience-inspired dynamic architecture, a dynamic artificial neural network array and a neural network array of electrodes associated with neural tissue such as a brain, the method and apparatus having a special purpose display processor. The special purpose display processor outputs a display over a period of selected reference time units to demonstrate a neural pathway from, for example, one or a plurality of input neurons through intermediate destination neurons to an output neuron in three-dimensional space. The displayed neural network may comprise neurons and synapses in different colors and may be utilized, for example, to show the behavior of a neural network for classifying hand-written digits between values of 0 and 9 or recognizing vertical/horizontal lines in a grid image of lines.

Abstract: This invention provides novel 3-amino propanamide selective androgen receptor degrader (SARD) compounds, pharmaceutical compositions and uses thereof in treating prostate cancer, advanced prostate cancer, castration resistant prostate cancer, androgenic alopecia or other 5 hyperandrogenic dermal diseases, Kennedy's disease, amyotrophic lateral sclerosis (ALS), and uterine fibroids, and to methods for reducing the levels of androgen receptor-full length (AR-FL) including pathogenic or resistance mutations, AR-splice variants (AR-SV), and pathogenic polyglutamine (polyQ) polymorphisms of AR in a subject.

Abstract: Methods useful for effecting prophylaxis or treatment of amyloidosis, including AA Amyloidosis and AL amyloidosis, by administering peptides comprising neoepitopes, such as AA fragments from a C-terminal region of AA, and antibodies specific for neoepitopes of aggregated amyloid proteins, for example, antibodies specific for the C-terminal region of AA fibrils. Antibodies for inhibition of formation and/or increasing clearance of amyloid deposits in a patient thus effecting prophylaxis or treating amyloid disease.

Abstract: Circuits and methods for power conversion. In some examples, a modular multi-level converter (MMC) is configured for power conversion between an alternating current (AC) bus and a direct current (DC) bus. The MMC includes submodules arranged into a phase leg for at least one phase of the AC bus. Each submodule includes an energy storage component and a switch configured for bypassing the energy storage component or connecting the energy storage component into the phase leg. The MMC includes a pre-charger circuit configured to pre-charge the energy storage components of the submodules. The pre-charger circuit is configured for providing a first DC voltage that is lower than a second DC voltage on the DC bus, and the pre-charger circuit is coupled to an end submodule of the phase leg.

Abstract: A method includes performing by a processor: receiving a first plurality of power system frequency measurements from a plurality of phasor measurement units (PMUs) in the power system over a first time interval, generating a first plurality of multi-dimensional ellipsoids based on the first plurality of power system frequency measurements, extracting a plurality of first graphic parameter values from the first plurality of multi-dimensional ellipsoids, respectively, performing a regression analysis on the plurality of first graphic parameter values to generate a predictive relationship between the plurality of first graphic parameter values and inertia values of the power system, receiving a second plurality of power system frequency measurements from the plurality of PMUs over a second time interval, generating a second plurality of multi-dimensional ellipsoids based on the second plurality of power system frequency measurements, extracting a plurality of second graphic parameter values from the second plura

Abstract: A silane-modified polyester blend comprising a polyester polymer homogeneously blended with silane molecules containing two or three alkoxy groups bound to the silicon atom, wherein said silane molecules are present in said polyester blend in an amount of 0.05-20 wt % (or, e.g., 0.05-10 wt %, 0.05-5 wt %, or 0.05-2 wt %). The polyester polymer may, in particular embodiments, be a polyhydroxyalkanoate, terephthalate-based polyester, adipate-based, or succinate-based polyester. The silane molecule may be according to the formula (R2O)2SiR3R4, wherein R2 groups are independently selected from alkyl groups containing 1-4 carbon atoms; and R3 and R4 are independently selected from OR2 groups and alkyl groups containing 1-12 carbon atoms, provided that at least one of R3 and R4 is an alkyl group, wherein the alkyl group optionally includes one or more heteroatoms selected from oxygen, nitrogen, halogen, sulfur, phosphorus, and silicon. Methods for producing the silane-modified polyester blend are also described.

Abstract: A system includes a controller that is configured to generate a node control signal and a plurality of switch control signals, a plurality of programmable emulators, each of the plurality of programmable emulators being configurable as one of a plurality of node types responsive to the node control signal, and a plurality of switches that are programmable to couple ones of the plurality of programmable emulators to each other responsive to the plurality of switch control signals.

Abstract: The present invention relates to a compound of formula XXII and a compound of formula 17ya, which are defined as anywhere in the specification, to a composition comprising the same, and to a method of using thereof in the treatment of various forms of cancer.

Abstract: This invention provides novel indole, indazole, benzimidazole, benzotriazole, indoline, quinolone, isoquinoline, and carbazole selective androgen receptor degrader (SARD) compounds, pharmaceutical compositions and uses thereof in treating hyperproliferations of the prostate including pre-malignancies and benign prostatic hyperplasia, prostate cancer, advanced prostate cancer, castration resistant prostate cancer, other AR-expressing cancers, androgenic alopecia or other hyper androgenic dermal diseases, Kennedy's disease, amyotrophic lateral sclerosis (ALS), abdominal aortic aneurysm (AAA), and uterine fibroids, and to methods for reducing the levels (through degradation) and/or activity (through inhibition) of any androgen receptor including androgen receptor-full length (AR-FL) including pathogenic and/or resistance mutations, AR-splice variants (AR-SV), and pathogenic polyglutamine (polyQ) polymorphisms of AR in a subject.

Abstract: Embodiments of the present disclosure pertain to delivery agents for delivering one or more active agents to desired cells (e.g., adipose stromal cells). The delivery agents generally include: (1) a particle; (2) one or more active agents carried by the particle; and (3) a targeting agent associated with the particle, where the targeting agent directs the delivery agent to the desired cells. Additional embodiments of the present disclosure pertain to methods for delivering active agents to adipose stromal cells through the use of the aforementioned delivery agents. In some embodiments, the methods include a step of associating the adipose stromal cells with the delivery agent such that the associating results in the delivery of the active agents into the adipose stromal cells. The associating can occur by administering the delivery agent to a subject for the treatment or prevention of obesity and related disorder or diseases in the subject.

Abstract: Codoped alkali and alkaline earth halide scintillators are described. More particularly, the scintillators are codoped with tetravalent ions, such as Ti4+, Zr4+, Hf4+, Ge4+. The codoping can alter one or more optical and/or scintillation property of the scintillator material. For example, the codoping can improve energy resolution. Radiation detectors comprising the scintillators and methods of detecting high energy radiation using the radiation detectors are also described.

Abstract: A lightweight concrete composition includes the concrete components, per yd3 of concrete: Type III Portland cement (lb/yd3) 200-900; metakaolin (lb/yd3) 100-520; calcium sulfoaluminate cement (CSA) (lb/yd3) 40-840; 3/8? lightweight expanded slate aggregate (lb/yd3) 70-550; lightweight fine expanded slate aggregate (lb/yd3) 300-550; expanded glass fine aggregate (0.5-1 mm) 35-90 (lb/yd3); expanded glass fine aggregate (1-2 mm) 35-90 (lb/yd3); water (lb/yd3) 300-350; CSA cement set retarder 0.015 to 0.06 oz per lb of CSA cement; high-range water-reducing admixture 120-1000 (fl. oz/yd3); hydration controlling admixture 0-80 (fl. oz/yd3); reinforcing non-metallic lightweight fibers <1.5? in length 0-8 (lb/yd3); wherein the concrete has a flexural strength of at least 600 psi at 12 hours, a density of 95 to 110 lb/ft3, and a compressive strength at 28 days of at least 7,000 psi. A lightweight concrete wythe and method of making a lightweight concrete wythe are also disclosed.

Abstract: A new and distinct cultivar of flowering dogwood tree, which produces both fully dark red bracts and lighter red to pink bracts is provided. This dogwood tree is botanically known as Cornus florida and referred to by the following cultivar name: ‘Erica's Appalachian Sunrise’.

Abstract: A new and distinct cultivar of flowering dogwood tree, which has fused bracts is provided. This dogwood tree is botanically known as Cornus kousa and referred to by the following cultivar name: ‘Melissa's Mountain Snowfall’.