Patents Assigned to University of the Free State
  • Publication number: 20160046077
    Abstract: The invention relates to an additive manufacturing system 10 for manufacturing a product 300 layer-by-layer. The system 10 includes a production arrangement 12 which is configured to manufacture a product 300 layer-by-layer upon receiving instructions from a control arrangement 32. The control arrangement 32 is operatively connected to the production arrangement 12 and is configured to control the operation of the production arrangement 12 by providing control instructions for each layer of a product 300 to be manufactured to the production arrangement 12. The system 10 includes an optical monitoring arrangement 14 which is configured to capture an image of a layer manufactured by the production arrangement and/or a layer of source material laid/placed over a previously manufactured layer of the product 300. The optical monitoring arrangement 14 is also configured to send the captured image to the control arrangement for processing.
    Type: Application
    Filed: August 17, 2015
    Publication date: February 18, 2016
    Applicant: Central University of Technology, Free State
    Inventor: lhar YADROITSAU
  • Publication number: 20150272535
    Abstract: This invention relates to a mammographic tomography test object (hereinafter referred to as a phantom) and more particularly, but not exclusively, to a mammographic tomography test phantom for use in the verification of image reconstruction positions in digital breast tomosynthesis. The phantom includes a body made from an approximately tissue equivalent x-ray attenuating material; an upper spacer located on top of the body, and a lower spacer located below the body, the spacers being made from a substantially non-compressible material; and a plurality of x-ray opaque granules located at predetermined positions within the body.
    Type: Application
    Filed: September 6, 2013
    Publication date: October 1, 2015
    Applicant: University of the Free State
    Inventors: Bernine Joson, William Ian Duncombe Rae
  • Patent number: 8790915
    Abstract: The present invention relates to the isolation and characterization of a protein responsible for the reduction of uranium (VI) to uranium (IV). The present invention extends to the use of the isolated protein in the reduction of uranium (VI) to uranium (IV) and further extends to a process for the bioremediation, or at least partial remediation, of a site contaminated with a source of U (VI). According to a first aspect thereof, the present invention provides an isolated polypeptide derived from Thermus scotoductus strain SA-01 that is responsible for the reduction of uranium (VI), in a source of uranium (VI), to uranium (IV), wherein the polypeptide comprises the amino acid sequence of SEQ ID No: 1.
    Type: Grant
    Filed: October 30, 2013
    Date of Patent: July 29, 2014
    Assignee: University of the Free State
    Inventors: Errol Duncan Cason, Esta Van Heerden, Lizelle Ann Piater, Abitha Gyanendra Jugdave, Jacquiline Van Marwijk
  • Patent number: 8685688
    Abstract: The present invention relates to the isolation and characterization of a protein responsible for the reduction of uranium (VI) to uranium (IV). The present invention extends to the use of the isolated protein in the reduction of uranium (VI) to uranium (IV) and further extends to a process for the bioremediation, or at least partial remediation, of a site contaminated with a source of U (VI). According to a first aspect thereof, the present invention provides an isolated polypeptide derived from Thermus scotoductus strain SA-01 that is responsible for the reduction of uranium (VI), in a source of uranium (VI), to uranium (IV), wherein the polypeptide comprises the amino acid sequence of SEQ ID No: 1.
    Type: Grant
    Filed: September 21, 2010
    Date of Patent: April 1, 2014
    Assignee: University of the Free State
    Inventors: Errol Duncan Cason, Esta Van Heerden, Lizelle Ann Piater, Abitha Gyanendra Jugdave, Jacqueline Van Marwijk
  • Publication number: 20130309758
    Abstract: A method and apparatus are provided for conducting a microbiological process on a bulk material in which a quantity of the bulk material is loaded onto a waterproof lining forming part of a bio cell with a heat transfer arrangement below the quantity of bulk material or within its volume, or both. The moisture content of the bulk material is controlled by periodic or intermittent distribution of water into the bulk material in order to promote microbiological activity within the bulk material by means of microbes that may be either naturally occurring within the bulk material or may be selected and introduced into the bulk material according to a desired result. A leachate recovery installation collects leachate draining from the bulk material. The temperature within the bulk material is monitored and the temperature controlled in order to elevate or decrease the temperature thereof to approach a target temperature associated with enhanced microbial activity of microbes present within the bulk material.
    Type: Application
    Filed: February 2, 2012
    Publication date: November 21, 2013
    Applicant: University of the Free State
    Inventors: Johan Erasmus, Estariethe Van Heerden
  • Patent number: 8501970
    Abstract: The invention relates to a novel process for the preparation of C-4 coupled flavonoids, proanthocyanidins and analogues thereof. According to a specific application of the invention, there is provided a method for the preparation of proanthocyanidins and proanthocyanidin analogues.
    Type: Grant
    Filed: June 5, 2009
    Date of Patent: August 6, 2013
    Assignee: University of the Free state
    Inventors: Jan Hendrik Van Der Westhuizen, Matthew Achilonu, Susanna Lucia Bonnet
  • Publication number: 20120289715
    Abstract: The invention relates to methods for the preparation of an optically inactive and optically active compounds which are selected from the group consisting of C-3 coupled biflavonoids and C-3 coupled biflavonoid analogues from a starting material or intermediate which are respectively selected from the group consisting of optically inactive or optically active flavan-3-ols and optically active flavan-3-ones, the method comprising the steps of (a) providing an optically inactive or active compound having a flavan-3-ol structure or a compound which is a flavan-3-one, (b) if a compound having a flavan-3-ol structure with a hydroxy group on the C-3 carbon is selected as starting material, converting the hydroxy group on the C-3 carbon of the compound having the flavan-3-ol structure to an oxo group to form a flavan-3-one of that compound, (c) providing a compound having a nucleophilic aromatic moiety, which compound is selected from the group of compounds having a nucleophilic aromatic moiety and which have flavono
    Type: Application
    Filed: August 19, 2010
    Publication date: November 15, 2012
    Applicant: University of the Free State
    Inventors: Jan Hendrik Van Der Westhuizen, Susanna Lucia Bonnet, Matthew Achilonu, Miroslav Sisa
  • Publication number: 20120276610
    Abstract: The present invention relates to the isolation and characterization of a protein responsible for the reduction of uranium (VI) to uranium (IV). The present invention extends to the use of the isolated protein in the reduction of uranium (VI) to uranium (IV) and further extends to a process for the bioremediation, or at least partial remediation, of a site contaminated with a source of U (VI). According to a first aspect thereof, the present invention provides an isolated polypeptide derived from Thermus scotoductus strain SA-01 that is responsible for the reduction of uranium (VI), in a source of uranium (VI), to uranium (IV), wherein the polypeptide comprises the amino acid sequence of SEQ ID No: 1.
    Type: Application
    Filed: September 21, 2010
    Publication date: November 1, 2012
    Applicant: University of the Free State
    Inventors: Errol Duncan Cason, Esta Van Heerden, Lizelle Ann Piater, Abitha Gyanendra Jugdave, Jacqueline Van Marwijk
  • Publication number: 20110160467
    Abstract: The invention relates to a novel process for the preparation of C-4 coupled flavonoids, proanthocyanidins and analogues thereof. According to a specific application of the invention, there is provided a method for the preparation of proanthocyanidins and proanthocyanidin analogues.
    Type: Application
    Filed: June 5, 2009
    Publication date: June 30, 2011
    Applicant: University of the Free State
    Inventors: Jan Hendrik Van Der Westhuizen, Mathew Achilonu, Susana Lucia Bonnet
  • Patent number: D824509
    Type: Grant
    Filed: June 15, 2017
    Date of Patent: July 31, 2018
    Assignee: University of the Free State
    Inventors: Zacharias A. Pretorius, Jozua Joubert