Patents Assigned to University of the Ryukyus
-
Publication number: 20220404363Abstract: As a technique enabling to simply and accurately diagnose human T cell leukemia virus type 1 (HTLV-1) related disease, there is provided a diagnostic method for an HTLV-1 related disease based on an amount of tumor necrosis factor receptor 2 (TNFR2) in a blood sample taken from a subject, wherein (1) it is determined based on an increase of the amount of TNFR2 that the subject suffers from, or is likely to develop, the HTLV-1 related disease; and/or (2) it is determined based on a decrease of the amount of TNFR2 that the subject is in remission, or is likely to be in remission, of the HTLV-1 related disease.Type: ApplicationFiled: November 2, 2020Publication date: December 22, 2022Applicants: NEC CORPORATION, UNIVERSITY OF THE RYUKYUSInventors: Yoshiko YOSHIHARA, Takuya FUKUSHIMA, Yuetsu TANAKA, Hiroaki MASUZAKI, Kennosuke KARUBE, Naoki IMAIZUMI
-
Publication number: 20220344416Abstract: An imaging sensor includes a photoelectric conversion element, and a plurality of transistors connected to the photoelectric conversion element. The plurality of transistors are configured to transmit charges generated by the photoelectric conversion element. The plurality of transistors includes at least one transistor that includes a silicon semiconductor layer and at least one other transistor that includes an oxide semiconductor layer.Type: ApplicationFiled: April 22, 2022Publication date: October 27, 2022Applicants: Samsung Electronics Co., Ltd., UNIVERSITY OF THE RYUKYUSInventors: Kyung Bae PARK, Hiroshi KAGEYAMA, Akira HIGA, Takashi NOGUCHI
-
Publication number: 20210196747Abstract: Provided is a metabolism improving agent that contains, for example, an alkalizing agent such as an acidosis improving agent or a urinary alkalizing agent as an active ingredient, and has actions such as improvement of insulin resistance, improvement of pituitary and adrenal functions, and reduction of visceral fat accumulation.Type: ApplicationFiled: May 24, 2019Publication date: July 1, 2021Applicants: University of the Ryukyus, Nippon Chemiphar Co., Ltd.Inventors: Hiroaki MASUZAKI, Hideki NAKAMURA, Toshitake HIRAI, Kaoru HARA, Takashi KANDA, Satomi YAMASAKI, Tadashi KOBAYASHI, Koichiro NISHIOKA
-
Publication number: 20200407690Abstract: Adipose-derived stem cells are isolated and extracted from an adipose tissue without using collagenase. An adipose tissue is covered with a nonwoven fabric sheet having sufficient interfiber space and pressed by an appropriate force. Thus, the adipose tissue infiltrates among fibers of the nonwoven fabric and then comes into contact with fibers surrounding the same. By immersing the nonwoven fabric as such in a culture medium, a number of adipose-derived stem cells are allowed to crawl out from the adipose tissue and then adhered to the fiber surface.Type: ApplicationFiled: February 27, 2019Publication date: December 31, 2020Applicants: University of the Ryukyus, ORTHOREBIRTH CO. LTD.Inventors: Hiroshi Sunami, Yusuke Shimizu, Naoko Futenma, Masashi Makita, Naoya Osaka
-
Patent number: 10863752Abstract: A plasma sterilization apparatus includes a voltage-applying unit that applies a voltage to a sterilization target having conductivity; a pair of electrodes that apply, in a discharged state, the voltage applied by the voltage-applying unit to the sterilization target via a dielectric; and a position changing unit that changes a relative position between the pair of electrodes and the sterilization target.Type: GrantFiled: October 27, 2016Date of Patent: December 15, 2020Assignees: National Institute of Technology, Saga University, University of the RyukyusInventors: Yoshihito Yagyu, Tatsuya Misawa, Akikazu Sakudo
-
Patent number: 10653740Abstract: A method of treating fatty liver comprising administering an effective amount of a plant belonging to a genus Cirsium to a patient in need of the treatment.Type: GrantFiled: February 23, 2018Date of Patent: May 19, 2020Assignees: Amino Up Co., Ltd., University of the Ryukyus, NPO Amami Functional Foods Study GroupInventors: Hirosuke Oku, Yasuo Kamiyama, Masashi Inafuku
-
Patent number: 10500242Abstract: An objective of the present invention is to provide a method for producing a nepodin-containing extract containing a high concentration of nepodin with less contaminants present therein thereby being able to be readily carried out on an industrial scale, when compared to the conventional techniques.Type: GrantFiled: February 21, 2017Date of Patent: December 10, 2019Assignees: UNIVERSITY OF THE RYUKYUS, OKINAWA RESEARCH CENTER CO., LTD.Inventors: Je-Tae Woo, Yuto Teruya, Kozue Sasaki, Toshiaki Teruya, Aki Yamano, Kosuke Sueyoshi, Miki Yamada
-
Publication number: 20190105363Abstract: An objective of the present invention is to provide a method for producing a nepodin-containing extract containing a high concentration of nepodin with less contaminants present therein thereby being able to be readily carried out on an industrial scale, when compared to the conventional techniques.Type: ApplicationFiled: February 21, 2017Publication date: April 11, 2019Applicants: OKINAWA RESEARCH CENTER CO., LTD., UNIVERSITY OF THE RYUKYUSInventors: Je-Tae WOO, Yuto TERUYA, Kozue SASAKI, Toshiaki TERUYA, Aki YAMANO, Kosuke SUEYOSHI, Miki YAMADA
-
Publication number: 20180317508Abstract: There is provided a plasma sterilization apparatus that permits plasma sterilization providing a uniform sterilization for even sterilization targets having various kinds of three-dimensional shape such as agricultural products, under mild conditions so as to prevent damage and quality deterioration of the targets. A plasma sterilization apparatus includes a voltage-applying unit that applies a voltage to a sterilization target having conductivity; a pair of electrodes that apply, in a discharged state, the voltage applied by said voltage-applying unit to the sterilization target via a dielectric; and a position changing unit that changes a relative position between the pair of electrodes and the sterilization target.Type: ApplicationFiled: October 27, 2016Publication date: November 8, 2018Applicants: NATIONAL INSTITUTE OF TECHNOLOGY, SAGA UNIVERSITY, UNIVERSITY OF THE RYUKYUSInventors: Yoshihito Yagyu, Tatsuya Misawa, Akikazu Sakudo
-
Patent number: 10018377Abstract: A solar light (heat) absorption material which has an excellent solar light (heat) absorbing ability and a simple structure, and may be used as a low-cost and high-performance heat absorption/accumulation material. Also, a solar light (heat) absorption/control building component including the solar light (heat) absorption material that allows for easy change of its solar light (heat) absorption/control ability. The material includes particles dispersed into a liquid medium having a specific heat ranging from 0.4 to 1.4 cal/g/° C. and a melting point of 5° C. or lower. The dispersed particles have L*value of 30 or less as determined by the CIE-Lab color system (light source D65).Type: GrantFiled: August 20, 2014Date of Patent: July 10, 2018Assignees: University of the Ryukyus, Osaka Gas Co., Ltd.Inventors: Yoshikazu Kondo, Masami Ueno, Yoshinobu Kawamitsu, Junichiro Tsutsumi
-
Publication number: 20150283196Abstract: The object of the invention is to provide a method of manufacturing a fraction containing nobiletin and tangeretin at high concentrations, which is excellent in terms of safety, economic efficiency, and the potential for industrialization.Type: ApplicationFiled: August 9, 2013Publication date: October 8, 2015Applicants: OKINAWA RESEARCH CENTER CO., LTD., UNIVERSITY OF THE RYUKYUSInventors: Toshiaki Teruya, Yuto Teruya, Saki Sugiyama, Je-Tae Woo
-
Publication number: 20150205896Abstract: For each (ij)-th tensor component, an equation ?F1(ij) using ?1 is computed based on a function W(F) of an inputted tensor amount F and a value (F=F?) of F. For each (kl)-th tensor component, an equation ˜?F2(kl) using ?1 and ?2 is computed based on the value (F=F?) of F. For each combination of an (ij)-th and a (kl)-th component, a function W(F?+?F1(ij)+˜?F2(kl)) is computed using the computed equations ?F1(ij) and ˜?F2(kl). For each (ij)-th component, a coefficient of ?1 in the function W(F?+?F1(ij)+˜?F2(kl)) is removed, and stress, based on a first order derivative with respect to the amount F of the function W(F), is computed. For each combination of an (ij)-th and a (kl)-th component, a coefficient of ?1·?2 in the function W(F?+?F1(ij)+˜?F2(kl)) is removed, and a material Jacobian, based on a second order derivative with respect to the amount F of the function W(F), is computed.Type: ApplicationFiled: September 6, 2013Publication date: July 23, 2015Applicant: UNIVERSITY OF THE RYUKYUSInventors: Masato Tanaka, Ryuji Omote, Takashi Sasagawa, Masaki Fujikawa
-
Patent number: 8658226Abstract: The present invention provides an agent having anti-Helicobacter pylori activity that is effective for the treatment, prevention or improvement of diseases associated with Helicobacter pylori and contains as an active ingredient thereof an extract of a plant belonging to the Labiatae family. The agent having anti-Helicobacter pylori activity of the present invention has superior heat stability and allows the obtaining of elimination effects in a short period of time.Type: GrantFiled: October 30, 2009Date of Patent: February 25, 2014Assignees: Japan Royal Jelly Co., Ltd., University of the RyukyusInventors: Yoshiya Sato, Hiromu Toma, Hironori Iwasaki, Kikuji Yamaguchi
-
Publication number: 20140030353Abstract: The invention provides a composition for prevention or treatment of a disease associated with the production of an autoantibody. Specifically, it provides a composition for the prevention or treatment of a disease associated with the production of an autoantibody, which comprise royal jelly as an active ingredient.Type: ApplicationFiled: September 27, 2013Publication date: January 30, 2014Applicant: University of the RyukyusInventors: Yoshiya SATO, Md. Kaiisar MANNOOR, Isao SHIMABUKURO, Kikuji YAMAGUCHI
-
Patent number: 8580274Abstract: An objective of the invention is to provide a drug delivery vehicle capable of allowing a vaccine or adjuvant to reach a target cell or tissue efficiently while being capable of improving the immunogenicity of the vaccine or capable of enhancing the immunostimulating effect of the adjuvant as well as a vaccine or adjuvant utilizing the same. Said drug delivery vehicle contains a multimeric protein having a coiled coil structure and a ligand molecule to a receptor of an immune cell.Type: GrantFiled: February 10, 2010Date of Patent: November 12, 2013Assignee: University of the RyukyusInventors: Takeshi Arakawa, Takeshi Miyata, Goro Matsuzaki, Takafumi Tsuboi
-
Publication number: 20130022641Abstract: To provide a pharmaceutical composition comprising a ceramide-related substance having little adverse side effects as an active ingredient by using a raw material that is highly safe to a human body and is inexpensive. A pharmaceutical composition comprising at least one sphingoglycolipid derivative that is produced from a beer waste and is represented by the formula below as an active ingredient: wherein R3 represents H or OH; R4 is as defined by (a) or (b) (a) when R3 is H, R4 represents (CH2)13CH3 or (CH2)6CH?CHCH2CH?CH(CH2)4CH3; and (b) when R3 is OH, R4 represents (CH2)yCH3 (where Y represents an integer of 13 to 21) or (CH2)Z1CH?CH(CH2)Z2CH3 (where Z1 and Z2 independently represent 0 or a natural number, provided that Z1+Z2=19).Type: ApplicationFiled: September 28, 2012Publication date: January 24, 2013Applicants: ORION BREWERIES, LTD., UNIVERSITY OF THE RYUKYUSInventors: Hirosuke Oku, Hironori Iwasaki, Kensaku Takara, Hisami Watanabe, Goro Matsuzaki, Takahiro Ishikawa, Kouji Takeuchi, Akira Taira
-
Patent number: 8216433Abstract: A plasma generator in which the variation of the impedance in the cavity before and after plasma is ignited is less and hardly affected by the shape of the cavity, and the ignitability of the plasma is improved and a method of generating plasma using the plasma generator are provided. The plasma generator comprises a nonconductive gas flow pipe (1) for introducing a gas (9) for generating plasma and discharging it into the atmosphere and a conductive antenna pipe (2) surrounding the gas flow pipe. A microwave (7) is applied to the antenna pipe to change the gas in the gas flow pipe into plasma. The plasma generator is characterized in that a slit (3) with a predetermined length is formed in the antenna pipe (2) along the axial direction of the gas flow pipe. Preferably, the plasma generator is characterized in that the length of the slit is an integral multiple of the half-wave length of the applied microwave.Type: GrantFiled: February 17, 2007Date of Patent: July 10, 2012Assignee: University of the RyukyusInventor: Akira Yonesu
-
Publication number: 20120100165Abstract: An objective of the invention is to provide a drug delivery vehicle capable of allowing a vaccine or adjuvant to reach a target cell or tissue efficiently while being capable of improving the immunogenicity of the vaccine or capable of enhancing the immunostimulating effect of the adjuvant as well as a vaccine or adjuvant utilizing the same. Said drug delivery vehicle contains a multimeric protein having a coiled coil structure and a ligand molecule to a receptor of an immune cell.Type: ApplicationFiled: February 10, 2010Publication date: April 26, 2012Applicant: University of the RyukyusInventors: Takeshi Arakawa, Takeshi Miyata, Goro Matsuzaki, Takafumi Tsuboi
-
Publication number: 20120017622Abstract: A solar light (heat) absorption material is provided which has an excellent solar light (heat) absorbing ability and a simple structure, and may be usable as a low-cost and high-performance heat absorption/accumulation material, the inventive material being usable also as a solar light (heat) absorption/control building component that allows easy change of its solar light (heat) absorption/control ability. The material comprises particles dispersed into a liquid medium having a specific heat ranging from 0.4 to 1.4 cal/g/° C. and a melting point of 5° C. or lower. The dispersed particles have L*value of 30 or less as determined by the CIE-Lab color system (light source D65).Type: ApplicationFiled: March 5, 2010Publication date: January 26, 2012Applicants: OSAKA GAS CO., LTD., UNIVERSITY OF THE RYUKYUSInventors: Yoshikazu Kondo, Masami Ueno, Yoshinobu Kawamitsu, Junichiro Tsutsumi
-
Publication number: 20110142955Abstract: The present invention relates to an agent for ameliorating stress-induced immune function modulation which comprises royal jelly. In addition, the present invention provides an anti-stress agent, pharmaceutical, food or beverage, or food additive that contains royal jelly as an active ingredient thereof and prevents or alleviates various somatic symptoms caused by stress.Type: ApplicationFiled: July 15, 2009Publication date: June 16, 2011Applicants: UNIVERSITY OF THE RYUKYUSInventors: Yoshiya Sato, Kaiissar Mannoor, Hisami Watanabe, Kikuji Yamaguchi, Mayu Tsukamoto