Patents Assigned to University of the Ryukyus
  • Publication number: 20240005544
    Abstract: A functional evaluation system of hippocampus that includes: an acquisition unit that acquires image data representing a hippocampus of a subject; and an identification unit that identifies volume data representing a volume of a left hippocampal-amygdaloid transition area of the subject, in accordance with the image data.
    Type: Application
    Filed: December 3, 2021
    Publication date: January 4, 2024
    Applicant: UNIVERSITY OF THE RYUKYUS
    Inventor: Shogo ISHIUCHI
  • Publication number: 20220404363
    Abstract: As a technique enabling to simply and accurately diagnose human T cell leukemia virus type 1 (HTLV-1) related disease, there is provided a diagnostic method for an HTLV-1 related disease based on an amount of tumor necrosis factor receptor 2 (TNFR2) in a blood sample taken from a subject, wherein (1) it is determined based on an increase of the amount of TNFR2 that the subject suffers from, or is likely to develop, the HTLV-1 related disease; and/or (2) it is determined based on a decrease of the amount of TNFR2 that the subject is in remission, or is likely to be in remission, of the HTLV-1 related disease.
    Type: Application
    Filed: November 2, 2020
    Publication date: December 22, 2022
    Applicants: NEC CORPORATION, UNIVERSITY OF THE RYUKYUS
    Inventors: Yoshiko YOSHIHARA, Takuya FUKUSHIMA, Yuetsu TANAKA, Hiroaki MASUZAKI, Kennosuke KARUBE, Naoki IMAIZUMI
  • Publication number: 20220344416
    Abstract: An imaging sensor includes a photoelectric conversion element, and a plurality of transistors connected to the photoelectric conversion element. The plurality of transistors are configured to transmit charges generated by the photoelectric conversion element. The plurality of transistors includes at least one transistor that includes a silicon semiconductor layer and at least one other transistor that includes an oxide semiconductor layer.
    Type: Application
    Filed: April 22, 2022
    Publication date: October 27, 2022
    Applicants: Samsung Electronics Co., Ltd., UNIVERSITY OF THE RYUKYUS
    Inventors: Kyung Bae PARK, Hiroshi KAGEYAMA, Akira HIGA, Takashi NOGUCHI
  • Publication number: 20210196747
    Abstract: Provided is a metabolism improving agent that contains, for example, an alkalizing agent such as an acidosis improving agent or a urinary alkalizing agent as an active ingredient, and has actions such as improvement of insulin resistance, improvement of pituitary and adrenal functions, and reduction of visceral fat accumulation.
    Type: Application
    Filed: May 24, 2019
    Publication date: July 1, 2021
    Applicants: University of the Ryukyus, Nippon Chemiphar Co., Ltd.
    Inventors: Hiroaki MASUZAKI, Hideki NAKAMURA, Toshitake HIRAI, Kaoru HARA, Takashi KANDA, Satomi YAMASAKI, Tadashi KOBAYASHI, Koichiro NISHIOKA
  • Publication number: 20200407690
    Abstract: Adipose-derived stem cells are isolated and extracted from an adipose tissue without using collagenase. An adipose tissue is covered with a nonwoven fabric sheet having sufficient interfiber space and pressed by an appropriate force. Thus, the adipose tissue infiltrates among fibers of the nonwoven fabric and then comes into contact with fibers surrounding the same. By immersing the nonwoven fabric as such in a culture medium, a number of adipose-derived stem cells are allowed to crawl out from the adipose tissue and then adhered to the fiber surface.
    Type: Application
    Filed: February 27, 2019
    Publication date: December 31, 2020
    Applicants: University of the Ryukyus, ORTHOREBIRTH CO. LTD.
    Inventors: Hiroshi Sunami, Yusuke Shimizu, Naoko Futenma, Masashi Makita, Naoya Osaka
  • Patent number: 10863752
    Abstract: A plasma sterilization apparatus includes a voltage-applying unit that applies a voltage to a sterilization target having conductivity; a pair of electrodes that apply, in a discharged state, the voltage applied by the voltage-applying unit to the sterilization target via a dielectric; and a position changing unit that changes a relative position between the pair of electrodes and the sterilization target.
    Type: Grant
    Filed: October 27, 2016
    Date of Patent: December 15, 2020
    Assignees: National Institute of Technology, Saga University, University of the Ryukyus
    Inventors: Yoshihito Yagyu, Tatsuya Misawa, Akikazu Sakudo
  • Patent number: 10653740
    Abstract: A method of treating fatty liver comprising administering an effective amount of a plant belonging to a genus Cirsium to a patient in need of the treatment.
    Type: Grant
    Filed: February 23, 2018
    Date of Patent: May 19, 2020
    Assignees: Amino Up Co., Ltd., University of the Ryukyus, NPO Amami Functional Foods Study Group
    Inventors: Hirosuke Oku, Yasuo Kamiyama, Masashi Inafuku
  • Patent number: 10500242
    Abstract: An objective of the present invention is to provide a method for producing a nepodin-containing extract containing a high concentration of nepodin with less contaminants present therein thereby being able to be readily carried out on an industrial scale, when compared to the conventional techniques.
    Type: Grant
    Filed: February 21, 2017
    Date of Patent: December 10, 2019
    Assignees: UNIVERSITY OF THE RYUKYUS, OKINAWA RESEARCH CENTER CO., LTD.
    Inventors: Je-Tae Woo, Yuto Teruya, Kozue Sasaki, Toshiaki Teruya, Aki Yamano, Kosuke Sueyoshi, Miki Yamada
  • Publication number: 20190105363
    Abstract: An objective of the present invention is to provide a method for producing a nepodin-containing extract containing a high concentration of nepodin with less contaminants present therein thereby being able to be readily carried out on an industrial scale, when compared to the conventional techniques.
    Type: Application
    Filed: February 21, 2017
    Publication date: April 11, 2019
    Applicants: OKINAWA RESEARCH CENTER CO., LTD., UNIVERSITY OF THE RYUKYUS
    Inventors: Je-Tae WOO, Yuto TERUYA, Kozue SASAKI, Toshiaki TERUYA, Aki YAMANO, Kosuke SUEYOSHI, Miki YAMADA
  • Publication number: 20180317508
    Abstract: There is provided a plasma sterilization apparatus that permits plasma sterilization providing a uniform sterilization for even sterilization targets having various kinds of three-dimensional shape such as agricultural products, under mild conditions so as to prevent damage and quality deterioration of the targets. A plasma sterilization apparatus includes a voltage-applying unit that applies a voltage to a sterilization target having conductivity; a pair of electrodes that apply, in a discharged state, the voltage applied by said voltage-applying unit to the sterilization target via a dielectric; and a position changing unit that changes a relative position between the pair of electrodes and the sterilization target.
    Type: Application
    Filed: October 27, 2016
    Publication date: November 8, 2018
    Applicants: NATIONAL INSTITUTE OF TECHNOLOGY, SAGA UNIVERSITY, UNIVERSITY OF THE RYUKYUS
    Inventors: Yoshihito Yagyu, Tatsuya Misawa, Akikazu Sakudo
  • Patent number: 10018377
    Abstract: A solar light (heat) absorption material which has an excellent solar light (heat) absorbing ability and a simple structure, and may be used as a low-cost and high-performance heat absorption/accumulation material. Also, a solar light (heat) absorption/control building component including the solar light (heat) absorption material that allows for easy change of its solar light (heat) absorption/control ability. The material includes particles dispersed into a liquid medium having a specific heat ranging from 0.4 to 1.4 cal/g/° C. and a melting point of 5° C. or lower. The dispersed particles have L*value of 30 or less as determined by the CIE-Lab color system (light source D65).
    Type: Grant
    Filed: August 20, 2014
    Date of Patent: July 10, 2018
    Assignees: University of the Ryukyus, Osaka Gas Co., Ltd.
    Inventors: Yoshikazu Kondo, Masami Ueno, Yoshinobu Kawamitsu, Junichiro Tsutsumi
  • Publication number: 20150283196
    Abstract: The object of the invention is to provide a method of manufacturing a fraction containing nobiletin and tangeretin at high concentrations, which is excellent in terms of safety, economic efficiency, and the potential for industrialization.
    Type: Application
    Filed: August 9, 2013
    Publication date: October 8, 2015
    Applicants: OKINAWA RESEARCH CENTER CO., LTD., UNIVERSITY OF THE RYUKYUS
    Inventors: Toshiaki Teruya, Yuto Teruya, Saki Sugiyama, Je-Tae Woo
  • Publication number: 20150205896
    Abstract: For each (ij)-th tensor component, an equation ?F1(ij) using ?1 is computed based on a function W(F) of an inputted tensor amount F and a value (F=F?) of F. For each (kl)-th tensor component, an equation ˜?F2(kl) using ?1 and ?2 is computed based on the value (F=F?) of F. For each combination of an (ij)-th and a (kl)-th component, a function W(F?+?F1(ij)+˜?F2(kl)) is computed using the computed equations ?F1(ij) and ˜?F2(kl). For each (ij)-th component, a coefficient of ?1 in the function W(F?+?F1(ij)+˜?F2(kl)) is removed, and stress, based on a first order derivative with respect to the amount F of the function W(F), is computed. For each combination of an (ij)-th and a (kl)-th component, a coefficient of ?1·?2 in the function W(F?+?F1(ij)+˜?F2(kl)) is removed, and a material Jacobian, based on a second order derivative with respect to the amount F of the function W(F), is computed.
    Type: Application
    Filed: September 6, 2013
    Publication date: July 23, 2015
    Applicant: UNIVERSITY OF THE RYUKYUS
    Inventors: Masato Tanaka, Ryuji Omote, Takashi Sasagawa, Masaki Fujikawa
  • Patent number: 8658226
    Abstract: The present invention provides an agent having anti-Helicobacter pylori activity that is effective for the treatment, prevention or improvement of diseases associated with Helicobacter pylori and contains as an active ingredient thereof an extract of a plant belonging to the Labiatae family. The agent having anti-Helicobacter pylori activity of the present invention has superior heat stability and allows the obtaining of elimination effects in a short period of time.
    Type: Grant
    Filed: October 30, 2009
    Date of Patent: February 25, 2014
    Assignees: Japan Royal Jelly Co., Ltd., University of the Ryukyus
    Inventors: Yoshiya Sato, Hiromu Toma, Hironori Iwasaki, Kikuji Yamaguchi
  • Publication number: 20140030353
    Abstract: The invention provides a composition for prevention or treatment of a disease associated with the production of an autoantibody. Specifically, it provides a composition for the prevention or treatment of a disease associated with the production of an autoantibody, which comprise royal jelly as an active ingredient.
    Type: Application
    Filed: September 27, 2013
    Publication date: January 30, 2014
    Applicant: University of the Ryukyus
    Inventors: Yoshiya SATO, Md. Kaiisar MANNOOR, Isao SHIMABUKURO, Kikuji YAMAGUCHI
  • Patent number: 8580274
    Abstract: An objective of the invention is to provide a drug delivery vehicle capable of allowing a vaccine or adjuvant to reach a target cell or tissue efficiently while being capable of improving the immunogenicity of the vaccine or capable of enhancing the immunostimulating effect of the adjuvant as well as a vaccine or adjuvant utilizing the same. Said drug delivery vehicle contains a multimeric protein having a coiled coil structure and a ligand molecule to a receptor of an immune cell.
    Type: Grant
    Filed: February 10, 2010
    Date of Patent: November 12, 2013
    Assignee: University of the Ryukyus
    Inventors: Takeshi Arakawa, Takeshi Miyata, Goro Matsuzaki, Takafumi Tsuboi
  • Publication number: 20130022641
    Abstract: To provide a pharmaceutical composition comprising a ceramide-related substance having little adverse side effects as an active ingredient by using a raw material that is highly safe to a human body and is inexpensive. A pharmaceutical composition comprising at least one sphingoglycolipid derivative that is produced from a beer waste and is represented by the formula below as an active ingredient: wherein R3 represents H or OH; R4 is as defined by (a) or (b) (a) when R3 is H, R4 represents (CH2)13CH3 or (CH2)6CH?CHCH2CH?CH(CH2)4CH3; and (b) when R3 is OH, R4 represents (CH2)yCH3 (where Y represents an integer of 13 to 21) or (CH2)Z1CH?CH(CH2)Z2CH3 (where Z1 and Z2 independently represent 0 or a natural number, provided that Z1+Z2=19).
    Type: Application
    Filed: September 28, 2012
    Publication date: January 24, 2013
    Applicants: ORION BREWERIES, LTD., UNIVERSITY OF THE RYUKYUS
    Inventors: Hirosuke Oku, Hironori Iwasaki, Kensaku Takara, Hisami Watanabe, Goro Matsuzaki, Takahiro Ishikawa, Kouji Takeuchi, Akira Taira
  • Patent number: 8216433
    Abstract: A plasma generator in which the variation of the impedance in the cavity before and after plasma is ignited is less and hardly affected by the shape of the cavity, and the ignitability of the plasma is improved and a method of generating plasma using the plasma generator are provided. The plasma generator comprises a nonconductive gas flow pipe (1) for introducing a gas (9) for generating plasma and discharging it into the atmosphere and a conductive antenna pipe (2) surrounding the gas flow pipe. A microwave (7) is applied to the antenna pipe to change the gas in the gas flow pipe into plasma. The plasma generator is characterized in that a slit (3) with a predetermined length is formed in the antenna pipe (2) along the axial direction of the gas flow pipe. Preferably, the plasma generator is characterized in that the length of the slit is an integral multiple of the half-wave length of the applied microwave.
    Type: Grant
    Filed: February 17, 2007
    Date of Patent: July 10, 2012
    Assignee: University of the Ryukyus
    Inventor: Akira Yonesu
  • Publication number: 20120100165
    Abstract: An objective of the invention is to provide a drug delivery vehicle capable of allowing a vaccine or adjuvant to reach a target cell or tissue efficiently while being capable of improving the immunogenicity of the vaccine or capable of enhancing the immunostimulating effect of the adjuvant as well as a vaccine or adjuvant utilizing the same. Said drug delivery vehicle contains a multimeric protein having a coiled coil structure and a ligand molecule to a receptor of an immune cell.
    Type: Application
    Filed: February 10, 2010
    Publication date: April 26, 2012
    Applicant: University of the Ryukyus
    Inventors: Takeshi Arakawa, Takeshi Miyata, Goro Matsuzaki, Takafumi Tsuboi
  • Publication number: 20120017622
    Abstract: A solar light (heat) absorption material is provided which has an excellent solar light (heat) absorbing ability and a simple structure, and may be usable as a low-cost and high-performance heat absorption/accumulation material, the inventive material being usable also as a solar light (heat) absorption/control building component that allows easy change of its solar light (heat) absorption/control ability. The material comprises particles dispersed into a liquid medium having a specific heat ranging from 0.4 to 1.4 cal/g/° C. and a melting point of 5° C. or lower. The dispersed particles have L*value of 30 or less as determined by the CIE-Lab color system (light source D65).
    Type: Application
    Filed: March 5, 2010
    Publication date: January 26, 2012
    Applicants: OSAKA GAS CO., LTD., UNIVERSITY OF THE RYUKYUS
    Inventors: Yoshikazu Kondo, Masami Ueno, Yoshinobu Kawamitsu, Junichiro Tsutsumi