Abstract: Provided are nanofunctional silica particles having excellent functionality and quality, and capable of being mass-produced at low costs. According to the present invention, there are provided nanofunctional silica particles including a coating layer containing one or more silica compounds selected from the group consisting of mercaptopropyl trimethoxysilane (MPS), mercaptopropyl triethoxysilane (MPES), mercaptopropyl methyldimethoxysilane (MPDMS), trimethoxy[2-(7-oxabicyclo[4.1.0]-hept-3-yl)ethyl]silane (EpoPS), thiocyanatopropyl triethoxysilane (TCPS), acryloxypropyl trimethoxysilane (ACPS), and aminopropyl trimethoxysilane (APS); and functional particles in the coating layer, and being used in imaging, assay, diagnosis, treatment or the like, medicine or bioresearch.

Abstract: In the present invention, when configuring a control system of an inverter performing power conversion between AC and DC, a frequency computation is performed based on biaxial voltage amounts obtained through two current regulators in such a way that each of biaxial component currents obtained by detecting an AC circuit current and performing a rotational coordinate transformation matches each respective command value and phase information in synchronization with an electromotive force power supply of the AC circuit is obtained by integrating the frequency to perform the rotational coordinate transformation of the AC current and also the inverter is caused to operate by generating a PWM switching signal from the biaxial voltage amounts to perform necessary power conversion control.

Abstract: A laser diode having nano patterns is disposed on a substrate. A first conductive-type clad layer is disposed on the substrate, and a second conductive-type clad layer is disposed on the first conductive-type clad layer. An active layer is interposed between the first conductive-type clad layer and the second conductive-type clad layer. Column-shaped nano patterns are arranged at a surface of the second conductive-type clad layer to form a laser diode such as a distributed feedback laser diode.

Abstract: A method for promoting expression of p53 mRNA and an expression promoting agent for use in the method are provided. The expression of the p53 gene can be promoted by inhibiting the binding between RNA transcribed from exon 1 of the vegf-A gene and mRNA transcribed from the p53 gene. The inhibition of the binding can be achieved by, for example, degrading the RNA transcribed from the exon 1 of the vegf-A gene, inhibiting transcription of RNA from the exon 1 of the vegf-A gene, or binding a nucleic acid that is different from the mRNA transcribed from the p53 gene to the RNA transcribed from the exon 1 of the vegf-A gene.

Abstract: To provide a brain-image diagnosis supporting method or the like. The method is a statistical evaluation method excluding the subjective judgment of an examiner, and enables image diagnosis. The method can present stable judgment criteria with respect to data on brain images imaged by a predetermined method in order to discriminate difficult diseases to diagnose. The method is also effective with respect to relationships which can not be always explained with a simple linear relationship, for example, the relationship between data on brain images imaged by a predetermined method and a disease which is a variable. By applying a predetermined nonlinear multivariate analysis method to data on brain images of a plurality of examinees imaged by a predetermined method and by classifying the data, image diagnosis support using a computer performed with respect to the data on brain images is performed. For example, SOM method is applied as a predetermined nonlinear multivariate analysis method.

Abstract: A laser diode having nano patterns is disposed on a substrate. A first conductive-type clad layer is disposed on the substrate, and a second conductive-type clad layer is disposed on the first conductive-type clad layer. An active layer is interposed between the first conductive-type clad layer and the second conductive-type clad layer. Column-shaped nano patterns are arranged at a surface of the second conductive-type clad layer to form a laser diode such as a distributed feedback laser diode.

Abstract: It is to provide a method for determining allergic diseases with a high sensitivity and accuracy which enables multilateral and global analysis with a minute amount of sample, even using body fluid other than blood such as saliva, nasal discharge and tears as a sample, particularly by suppressing nonspecific reaction as much as possible.

Abstract: An Nb3Sn wire rod having a high Jc value is manufactured using an Ag—Sn alloy. A composite rod including a plurality of Nb core materials incorporated in an Ag—Sn alloy matrix material having an Sn concentration of 9.35 to 22.85 at % is prepared. Next, the composite rod is extruded and/or wire drawn while carrying out process annealing of 350 to 490° C., followed by heat treatment at 500 to 900° C. to produce an Nb3Sn filament. Thus, an Nb3Sn extrafine multi-core superconducting wire is manufactured.

Abstract: An object of the present invention is to provide a method for predicting the risk of acquiring influenza, which is characterized by low price, low invasiveness, and applicability to total automation. The present invention provides a method for predicting the risk of acquiring influenza, which comprises measuring the ratio of anti-influenza IgA to the total IgA in a specimen collected from a subject.

Abstract: Disclosed herein is a high-quality group III-nitride semiconductor thin film and group III-nitride semiconductor light emitting device using the same. To obtain the group III-nitride semiconductor thin film, an AlInN buffer layer is formed on a (1-102)-plane (so called r-plane) sapphire substrate by use of a MOCVD apparatus under atmospheric pressure while controlling a temperature of the substrate within a range from 850 to 950 degrees Celsius, and then, GaN-based compound, such as GaN, AlGaN or the like, is epitaxially grown on the buffer layer at a high temperature. The group III-nitride semiconductor light emitting device is fabricated by using the group III-nitride semiconductor thin film as a base layer.

Abstract: Disclosed is a method for stimulating revascularization in a subject comprising the steps of: (a) administering erythropoietin to the subject; (b) collecting peripheral blood mononuclear cells from the subject; and (c) administering the collected peripheral blood mononuclear cells to a target site of the subject. Peripheral blood mononuclear cells, and particularly CD34-positive cells, are mobilized into the peripheral blood of a subject by the administration of erythropoietin to the subject. The method of the present invention is useful for the treatment of ischemic diseases, such as peripheral vascular disorder.

Abstract: A group III nitride semiconductor thin film and a group III nitride semiconductor light emitting device using the same. The group III nitride semiconductor thin film includes a substrate with a concave and convex portions formed thereon; a buffer layer formed on the substrate and made of a group III nitride; and an epitaxial growth layer formed on the buffer layer and made of (11-20) plane gallium nitride. The group III nitride light emitting device includes the group III nitride semiconductor thin film. The present invention allows a high quality a-plane group III nitride semiconductor thin film and a group III nitride semiconductor light emitting device using the same.

Abstract: A polyoxyalkylene chain-containing lipid derivative, which is represented by the following formula (1): wherein L, Y, W, X1, X2, X3, OA, Z, m1, m2, m3, n1, n2 and n3 are as defined in the specification.

Abstract: Included in the digital filtering equipment for extracting a feature quantity from a speech signal in order to execute a speech recognition based on an inputted speech signal are: a) an waveform determining section for obtaining an inputted speech signal and quantizing the speech signal waveform; b) a division value operating section for summing a quantized signal data in a prescribed adjoining region to divide the summation value by the number of summed data, with respect to a data quantized at each point by the waveform determining section, whereby a division value is obtained with the data being centered; c) a comparison section for comparing a division value calculated by the division value operating section and the quantized data calculated in the division value operating section to output logical truth of a comparison result, with respect to each data; and d) a conversion section for converting the quantized data into the selected data points based on an output from the comparison section.

Abstract: A laser diode having nano patterns is disposed on a substrate. A first conductive-type clad layer is disposed on the substrate, and a second conductive-type clad layer is disposed on the first conductive-type clad layer. An active layer is interposed between the first conductive-type clad layer and the second conductive-type clad layer. Column-shaped nano patterns are arranged at a surface of the second conductive-type clad layer to form a laser diode such as a distributed feedback laser diode.

Abstract: A biodevice is in an elongated form and has a conductive layer and an insulating layer stacked on a side surface of a shaft member at the center. A cylindrical hollow section is formed through the device, being connected to the exterior at a front end and extending from this front end axially. An electrode section is formed on an inner surface. A sensing substance such as enzyme may be placed at the electrode section to detect a current value corresponding to the concentration or quantity of an object under test placed between a counter electrode and the biodevice.

Abstract: A system of quantitatively determining a biomolecule, which has: allowing fluorescent silica particles capable of emitting fluorescence detectable by a flow cytometer to capture a target biomolecule fluorescent-labelled for quantitative determination; detecting the fluorescence emitted from the fluorescent silica particles themselves by using the flow cytometer; and measuring the intensity of the fluorescence of the labelled target biomolecule, thereby quantitatively determining the target biomolecule.

Abstract: The present inventors tested the effects of interferons on the expression of HLA-A in cells and cell injury caused by anti-HLA class I antibodies, by using a 2D7-DB antibody as an anti-HLA class I antibody and the IM-9 cell line as the cells to be tested. As a result, the expression of HLA-A was demonstrated to be upregulated by IFN? or IFN?, Furthermore, WST-8 assays were performed to examine the cell viability when an interferon and an anti-HLA class I antibody were used in combination. As a result, cell death activity was found to be increased by the combination of 2D7-DB and IFN? or IFN?.

Abstract: A transmission unit emits an electromagnetic wave having the same frequency f as an output signal from a sending unit in a direction of a measurement axis. A detecting unit performs synchronous detection on a reflected wave detected by a directional coupler by an in-phase signal and a quadrature signal of the transmission signal, and by extracting DC component from the detection signal, detects the in-phase component and quadrature component of the reflected wave. An analysis signal generating unit mixes the in-phase component and quadrature component of the reflected wave and signals having periodicity corresponding to a prescribed distance, and using only one of the resulting side bands, generates an analysis signal. Fourier transform unit finds distance to the object of measurement from a profile obtained by Fourier transform of the analysis signal.

Abstract: Colloidal silica particles containing a fluorescent dye compound, composed of a silica particle containing a silica component and a fluorescent dye compound chemically bound or adsorbed thereto, wherein the colloidal silica particles containing a fluorescent dye compound have an average diameter of 30 nm or less, and wherein said silica particles are used simultaneously as fluorescent-labelling nanobeads; a fluorescent nano-material comprising said colloidal silica particles; and a biochip and an assay method using the same.