Abstract: The invention relates to a mobile communication system. The mobile communication system includes a first base station configured to transmit at least part of a first data set of data segments arranged in a first sequence to a user terminal, and a second base station configured to transmit at least part of the first data set of data segments arranged in a second sequence to the user terminal, the second sequence of the first data set being an inverse of the first sequence of the first data set. The invention also relates to a coordination component, base station and user terminal for use in this system and to a method of arranging data segments in sequences performed by the coordination component. The invention further relates to a method of transmitting an acknowledgement, performed by the base station or by the user terminal.

Abstract: The present invention describes a method and device for improving the capture and interrogation of a rare cell population in a biological fluid such as in circulating tumor cells (CTC) in blood or Diagnostic Leukapheresis. ReFLECT-CTC is designed to capture CTC in a continuous fashion and interrogate isolated individual CTC. ReFLECT-CTC has the advantage of sampling large volumes of a biological sample which is especially useful in assessing the heterogeneity of a CTC population. The invention has application in cancer diagnostics where assessing tumor cells found in individual cancer patients will determine which drugs are most likely to be effective for an individual.

Abstract: The present invention discloses a device and methods for the analysis of secreted molecules from a single cell. As described herein, the invention incorporates individual microwells with a bottom surface capable of capturing a cell and allows the release of secreted molecules to be printed onto a capture surface. The device provides accurate identification of the cell source of the printed molecules by mapping the printed molecules to the cell source. The invention further employs spectrometry, immunoassay or label free Surface Plasmon Resonance imaging for detection of the secreted molecules in combination with a microwell array, where single cells are seeded in individual microwells and the secreted molecules are captured by the capture surface in an array print while the cell remains in the microwell for additional interrogation. The present invention has applications in medical research and diagnosis where individual target cells in a fluid sample are interrogated for the secreted products.

Abstract: The disclosure relates to a transmission node and a method for wirelessly providing a number of data packets to a plurality of receivers in a cell of a transmission node of a cellular telecommunications system. The method comprises the steps of storing a number of network coded data packets at the transmission node and cyclically transmitting the stored network coded data packets from the transmission node to the plurality of receivers. The number of transmitted network coded data packets in a cycle is at least equal to the number of data packets to be provided to each receiver of the plurality of receivers and each network coded data packet is a linear combination of two or more data packets to be provided to each receiver.

Abstract: Methods, systems and activated human mesenchymal stromal cells (hMSCs) from bone marrow regions distal from bone fractures, the hMSCs enhanced for encouraging healing of bone fractures. Systems and methods of activation for enhancing bone fracture healing hMSCs, and the enhanced cells themselves, by exposing and activating distally obtained bone marrow aspirate to acoustic energy prior to placement of the activated cells at a site of a bone fracture.

Abstract: A Silicon On Insulator current source array includes input control for receiving a control voltage, a first reference input for receiving a first reference voltage, and a second reference input for receiving a second reference voltage. A chain of several Silicon On Insulator MOS transistors, of the same type, have control electrodes all connected to the input control, first conduction electrodes are all connected to the first reference input, and second conduction electrodes are respectively connected to the second reference input through several load circuits respectively configured to be traversed by several currents when the several transistors are ON upon application of the control voltage on the input control. An input bias is coupled to a semiconductor well located below an insulating buried layer located below the chain of transistors for receiving a biasing voltage difference.

Abstract: The invention relates to composition comprising a dextran-tyramine conjugate and a conjugate selected from the group consisting of chondroitin sulphate-tyramine, collagen-tyramine, chitosan-tyramine, chitosan-phloretic acid, gelatine-tyramine, heparan sulphate-tyramine, keratin sulphate-tyramine, hyaluronic acid-tyramine and heparin-tyramine.

Abstract: The invention relates to a dextran-based tissuelette comprising platelet-rich plasma lysate (PRPL), which can be used for tissue repair. In particular, the tissuelette of the present invention can be adapted to display properties similar to natural cartilage, while having increased chondrocyte-attraction. Also, it has a tunable biostability that allows for degradation of the tissuelette material during natural tissue regeneration. In addition, the tissuelette displays full and covalent integration with the surrounding tissue when prepared directly at the site requiring tissue repair. The tissuelette of the present invention is primarily meant for use in cartilage repair, in particular cartilage repair upon degradation by osteoarthritis.

Abstract: The present invention relates to a process for the preparation of branched biodegradable polymers comprising of the steps of: (a) preparing a macromonomer by ring-opening polymerization of at least one cyclic ester, cyclic carbonate, and/or cyclic carboxyanhydride in the presence of a branching agent and optionally a catalyst; and (b) subsequent polycondensation of the macromonomer, to a process for the preparation of a macromonomer by ring-opening polymerization of at least one cyclic ester, carbonate and/or N-carboxyanhydride in the presence of a defined branching agent and optionally a catalyst, according to step (a), and to the prepared macromonomer and branched biodegradable polymer and their uses.

Abstract: The present invention relates to a VHH which binds to a growth factor or is an antagonist for a growth factor, or binds to an implant.

Abstract: The present invention discloses a method for the intercalation of a chromophore within channels of a zeolite L crystal. The intercalated chromophores exhibit J type aggregation of the chromophores within the channels of the zeolite L crystals. The invention discloses method parameters which lead to the J type aggregation of the chromophores within the channels of the zeolite L crystals. The J type aggregation of the chromophores affords unique florescent properties rendering the intercalated zeolite L crystals as a material for use in novel optoelectronic devices.

Abstract: The present invention discloses a method for the intercalation of a chromophore within channels of a zeolite L crystal. The intercalated chromophores exhibit J type aggregation of the chromophores within the channels of the zeolite L crystals. The invention discloses method parameters which lead to the J type aggregation of the chromophores within the channels of the zeolite L crystals. The J type aggregation of the chromophores affords unique florescent properties rendering the intercalated zeolite L crystals as a material for use in novel optoelectronic devices.