Patents Assigned to University of Washington Office of Technology Licensing
  • Novel sequence variants of multi-drug resistance genes, MDR1 and MRP1, and recombinant cells expressing MRP1 and MDR1 for assessment of drug penetration and disposition
    Publication number: 20060024685
    Abstract: Provided are compositions relating to novel MDR1 polymorphisms, including nucleic acids, polypeptides, and recombinant cells, as well as methods for detection of MDR1 polymorphisms in biological samples and elucidation of the influence of MDR1 polymorphisms on MDR1 protein function. Also provided are a rat MRP1 cDNA and protein, stable cell lines expressing the rat MRP1 protein, and methods of assessing drug penetration or disposition in a cell line expressing a recombinant mammalian MRP1 or MDR1 protein, or a homolog thereof.
    Type: Application
    Filed: January 26, 2005
    Publication date: February 2, 2006
    Applicant: University of Washington, Office of Technology Licensing
    Inventors: Rodney Ho, Ziping Yang, Danny Shen, Daniel Wu
  • Ancestral and COT viral sequences, proteins and immunogenic compositions
    Publication number: 20050137387
    Abstract: The present invention is directed to ancestral and COT nucleic acid and amino acid sequences, methods for producing such sequences and uses thereof, including prophylactic and diagnostic uses.
    Type: Application
    Filed: February 17, 2004
    Publication date: June 23, 2005
    Applicant: University of Washington Office of Technology Licensing
    Inventors: James Mullins, Allen Rodrigo, Gerald Learn, Fusheng Li, David Nickle, Mark Jensen