Abstract: The use of at least one GnRH analogue for the preparation of a medicament for the prevention and/or treatment of side effects of ovarectomy or symptoms associated with reproductive senescence in female mammals, in particular urinary incontinence, hot flushes, and skin/hair changes are disclosed.
Abstract: The use of at least one GnRH analogue for the preparation of a medicament for the prevention and/or treatment of side effects of ovarectomy or symptoms associated with reproductive senescence in female mammals, in particular urinary incontinence, hot flushes, and skin/hair changes are disclosed.
Abstract: The present invention relates to a soluble hybrid protein, comprising at least a first polypeptide sequence derived from a prion protein PrPc that is capable of binding a protein responsible for transmissible spongiform encephalitis (PrPSc), and a second polypeptide sequence (tag), wherein said hybrid protein does not comprise a functional membrane anchor moiety. Also, the present invention is directed to the use of said hybrid proteins for the diagnosis of transmissible spongiform encephalopathies. In addition, the present invention relates to the use of said hybrid protein, a nucleic acid encoding said hybrid protein, a vector, and/or a host cell comprising a nucleic acid encoding said hybrid protein for the preparation of a medicament for the prevention or treatment of transmissible spongiform encephalopathies (TSEs).
Type:
Application
Filed:
March 12, 2004
Publication date:
November 20, 2008
Applicant:
University of Zuerich
Inventors:
Adriano Aguzzi, Nicolas Genoud, Alex Raeber
Abstract: A seat component to prevent whiplash injury during a rapid motion change of a vehicle comprises means allowing a displacement of the seat and a person sitting thereon backwards (22) in relation to the direction of movement at the motion change. These means comprise a body (11, 18) to be affixed to or being part of the seat, a slide element (16) affixed to the vehicle and being in guiding contact with said body to guide a translational displacement of the seat over a predetermined distance. It further comprises a trigger system (13) to detect a acceleration threshold, a release mechanism (14) controlled through the trigger system (13) to enable said translational displacement (22) and a damping component (17) to damp said translational displacement (22). The trigger system (13) opens the release mechanism (14) only upon detection of an acceleration value above a predetermined threshold.