Patents Assigned to University Research Foundation
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Patent number: 10586640Abstract: A bulk high performance permanent magnet comprising a neodymium-iron-boron core having an outer surface, and a coercivity-enhancing element residing on at least a portion of said outer surface, with an interior portion of said neodymium-iron-boron core not having said coercivity-enhancing element therein. Also described herein is a method for producing the high-coercivity bulk permanent magnet, the method comprising: (i) depositing a coercivity-enhancing element on at least a portion of an outer surface of a neodymium-iron-boron core substrate to form a coated permanent magnet; and (ii) subjecting the coated permanent magnet to a pulse thermal process that heats said outer surface to a substantially higher temperature than an interior portion of said neodymium-iron-boron core substrate, wherein said substantially higher temperature is at least 200° C.Type: GrantFiled: January 25, 2017Date of Patent: March 10, 2020Assignees: UT-BATTELLE, LLC, IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC., LAWRENCE LIVERMORE NATIONAL SECURITY, LLCInventors: Mariappan Parans Paranthaman, Michael A. McGuire, David S. Parker, Orlando Rios, Brian C. Sales, Huseyin Ucar, Scott K. McCall, R. William McCallum, Cajetan I. Nlebedim
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Publication number: 20200069843Abstract: The present disclosure provides a method for preparing a decellularized muscle scaffold, decellularized muscle scaffolds produced therefrom, and uses thereof to treat a subject with damaged or lost muscle.Type: ApplicationFiled: May 18, 2018Publication date: March 5, 2020Applicant: Colorado State University Research FoundationInventors: Ruth J. Rose, Nicole P. Ehrhart, Matthew E. Randolph, Laura Chubb
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Patent number: 10576270Abstract: Example devices and methods of tongue stimulation for communication of information to a user are disclosed herein. In an example, a tongue stimulation device may include a body configured to be placed entirely within a mouth of the user and atop the tongue of the user. An array of electro-tactile elements may be distributed on the body, wherein each of the electro-tactile elements is configured to stimulate an area of the tongue adjacent the electro-tactile element. A wireless receiver coupled to the body may be configured to receive stimulation information wirelessly from outside the mouth of the user. At least one processing unit coupled to the body may be configured to transform the received stimulation information into a stimulation signal for each of the electro-tactile elements, and to provide the stimulation signals to the electro-tactile elements.Type: GrantFiled: May 14, 2018Date of Patent: March 3, 2020Assignee: Colorado State University Research FoundationInventors: John D. Williams, Joel A. Moritz, Leslie M. Stone-Roy
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Patent number: 10576093Abstract: The present invention provides modified metformin compounds, particularly mito-metformin compounds, and pharmaceutical compositions thereof. Methods of using the compounds to provide neuroprotection and in the treatment and/or prevention of neurodegenerative diseases are also described.Type: GrantFiled: April 26, 2018Date of Patent: March 3, 2020Assignees: Iowa State University Research Foundation, Inc., The Medical College of Wisconsin, Inc.Inventors: Anumantha Kanthasamy, Balaraman Kalyanaraman
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Patent number: 10577544Abstract: The present application discloses low temperature, low pressure methods (LTLP) for upgrading and/or stabilizing bio-oil or a bio-oil fraction. One method comprises providing a bio-oil or bio-oil fraction and hydrogen, which are reacted in the presence of a catalyst at a temperature of less than 150° C. and a pressure of less than 100 bar (absolute) to produce a hydrogenated liquid oil at a carbon yield of over 75%. Another method comprises providing a bio-oil or bio-oil fraction, providing oxygen reducing reaction conditions, and reacting the bio-oil or bio-oil fraction under the oxygen reducing reaction conditions at LTLP to produce an upgraded bio-oil product containing fewer carbonyls than the bio-oil or bio-oil fraction. Yet another method comprises providing a bio-oil or bio-oil fraction and a solution comprising one or more fermentation organisms and a sugar source. The solution and bio-oil or bio-oil fraction are combined to obtain a fermentation mixture, which is incubated at 15° C. to 30° C.Type: GrantFiled: April 15, 2015Date of Patent: March 3, 2020Assignee: Iowa State University Research Foundation, Inc.Inventors: Marjorie Rover, Robert C. Brown, Patrick H. Hall, Ryan G. Smith
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Publication number: 20200060616Abstract: Implementations described and claimed herein provide systems and methods for managing animal patient during a veterinary procedure. In one implementation, a base has an interior surface, an exterior surface, and an opening. An electrode is disposed in the opening. The electrode is configured to communicate with medical device(s) for monitoring vital(s) of the patient during the procedure. A thermal insulator extends from the base. The thermal insulator forms a housing. An internal cavity is defined within the housing. The foot of the patient is receivable into the internal cavity. The thermal insulator regulates the body temperature of the animal patient during the veterinary procedure by retaining heat within the internal cavity.Type: ApplicationFiled: August 21, 2019Publication date: February 27, 2020Applicant: Colorado State University Research FoundationInventor: Natalie M. Malkut
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Patent number: 10570238Abstract: The present invention relates to a block copolymer comprising at least one PA block and at least one PB block. The PA block represents a polymer block comprising one or more units of monomer A, and the PB block represents a polymer block comprising one or more units of monomer B. Monomer A is a vinyl, acrylic, diolefin, nitrile, dinitrile, or acrylonitrile monomer. Monomer B is a radically polymerizable plant oil monomer containing one or more triglycerides. The present invention also relates to a method of preparing a thermoplastic block copolymer by radical polymerizing a radically polymerizable monomer with a radically polymerizable plant oil monomer containing one or more triglycerides, in the presence of an initiator and a transition-metal catalyst system to form the thermoplastic block copolymer. The polymerized plant oil-based block copolymers are useful in a variety of applications, such as asphalt modifiers, rubber compositions, adhesives, tires, in the automobile industry, footwear, packaging, etc.Type: GrantFiled: February 14, 2018Date of Patent: February 25, 2020Assignee: Iowa State University Research Foundation, Inc.Inventors: Eric William Cochran, Ronald Christopher Williams, Nacu Hernandez, Andrew A. Cascione
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Patent number: 10570286Abstract: The present invention relates to relates to a method of producing an improved asphalt. This method includes providing an asphalt binder and providing a compound of formula (I): as described herein. The asphalt binder is mixed with the compound of formula (I) under conditions effective to produce an improved asphalt. Also disclosed are an asphalt product and a method of making asphalt material.Type: GrantFiled: August 30, 2017Date of Patent: February 25, 2020Assignee: Iowa State University Research Foundation, Inc.Inventors: Ronald Christopher Williams, Joseph H. Podolsky, Nacu Hernandez, Eric W. Cochran, Austin Hohmann, Mohamed Elkashef
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Patent number: 10570359Abstract: An algal growth system can include a frame and a flexible sheet material that can have a substantially vertical orientation, where the flexible sheet material can be configured to facilitate the growth and attachment of algae, where the flexible sheet material can be supported by the frame. The algal growth system can include a first drive shaft, where the first drive shaft can be coupled with the frame, where the first drive shaft can support and actuate the flexible sheet material, a gear system, where the gear system can be coupled with the first drive shaft, a first roller, where the first roller can be coupled with the frame and can be configured to guide the flexible sheet material, and a drive motor, where the drive motor can be coupled with the gear system, where the drive motor can actuate the gear system and the at least one drive shaft such that the flexible sheet material can be actuated.Type: GrantFiled: December 21, 2018Date of Patent: February 25, 2020Assignees: GROSS-WEN TECHNOLOGIES, INC., IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC.Inventors: Martin Anthony Gross, Zhiyou Wen
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Publication number: 20200055951Abstract: The present invention relates to an antibody specifically binding to a pancreatic adenocarcinoma upregulated factor (PAUF) protein and use thereof. The antibody of the present invention binds to a PAUF protein with high specificity and affinity and thereby inhibits the proliferation, migration, invasion, and in vivo growth, and thus the antibody of the present invention can be effectively used in the field of diagnosis and treatment of diseases such as cancer in which PAUF proteins are overexpressed.Type: ApplicationFiled: August 16, 2017Publication date: February 20, 2020Applicants: DONG-A UNIVERSITY RESEARCH FOUNDATION FOR INDUSTRY-ACADEMY COOPERATION, PRESTIGE BIOPHARMA PTE. LTD.Inventors: Sang Seok KOH, Yeon Jeong KIM, So Eun YOUN, Song Cheol KIM, Seung-Mo HONG, Seong Yun JEONG
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Publication number: 20200054396Abstract: A novel microwave ablation applicator includes a flexible tubular shaft and a partially encapsulated antenna. The applicator is adapted to be used with an endoscope in order to access remote targets deep within an organ of a patient. Microwave power is emitted from the antenna in a desired radiation pattern by circulating an attenuating liquid through the shaft and across a portion of the antenna. Microwave ablation systems and methods are described.Type: ApplicationFiled: January 26, 2018Publication date: February 20, 2020Applicants: Broncus Medical Inc., Kansas State University Research FoundationInventors: Austin Pfannenstiel, Thomas M Keast, Henky Wibowo, Punit Prakash
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Publication number: 20200056172Abstract: The present invention relates to a DNA-peptide complex with a high-density functional group, a DNA-peptide-nanomaterial complex and a method for production of the same, a DNA-metal nanowire, and a method for production of the same. The DNA-peptide complex with a high-density functional group may include a DNA molecule; and a peptide containing an amino acid sequence capable of binding to the DNA molecule, wherein the peptide contains at least one functional group at a terminal thereof, wherein the peptide binds to the DNA molecule via at least one of electrostatic interaction, intercalation, and groove binding.Type: ApplicationFiled: October 31, 2017Publication date: February 20, 2020Applicants: Research & Business Foundation Sungkyunkwan University, Sogang University Research FoundationInventors: Jung Heon LEE, Kyu Bong JO, Kyung Il KIM, Seong Hyun LEE, Su Ji KIM, Xuelin JIN
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Publication number: 20200055013Abstract: Provided is a bubble volume control method and apparatus, and more particularly, to a bubble volume control method and apparatus for controlling the volume of a bubble by increasing or decreasing the volume of the bubble by emitting an ultrasonic wave having a resonance frequency corresponding to the size of the bubble located at the bottom of a container containing a liquid, such as water with bubbles composed of air, vapor, etc., toward the bubble by using an ultrasonic generator above the container, and maximizing a function of adjusting the volume of a bubble through a resonance effect by adjusting a liquid surface height of a liquid with the bubble according to a wavelength of an emitted ultrasonic wave.Type: ApplicationFiled: March 6, 2018Publication date: February 20, 2020Applicant: SOGANG UNIVERSITY RESEARCH FOUNDATIONInventors: Gihun SON, Jaewon LEE
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Patent number: 10564122Abstract: An electrophoresis chip-based setup for detection of different ions in buffer solution. The device is able to differentiate ions in, e.g., real soil or other solutions, and to detect concentration of a specific ion in the solution. Fabrication of the electrophoresis chip can use a soft lithography based molding process. The chip can be made out of PDMS on a glass substrate where on-chip valves were used to control timing of injecting sample and buffer solutions. Detection electrodes are used to detect the presence of ions over a period of several minutes. A controllable high voltage power supply system and related signal acquisition, processing and detection setup can be implemented with the sensor in a system. A microfluidic system for automated collection of soil sample through a porous ceramic and using vacuum suction can be used.Type: GrantFiled: October 20, 2017Date of Patent: February 18, 2020Assignee: Iowa State University Research Foundation, Inc.Inventors: Zhen Xu, Liang Dong, Ratnesh Kumar
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Patent number: 10562978Abstract: The invention includes monoclonal and polyclonal antibodies, and antigen-binding fragments thereof, having specific binding affinity for 4,6-diamino-5-(formylamino)pyrimidine (FAPY-adenine); hybridomas producing such antibodies; immunoconjugates comprising an antibody or antigen-binding fragment of the invention coupled to a moiety; and in vitro and in vivo methods for using such antibodies, antibody fragments, and conjugates based on binding to FAPY-adenine; nucleic acids encoding the heavy and/or light chains of the antibodies; vectors comprising the nucleic acid sequences encoding the heavy and/or light chains; host cells comprising and, optionally, expressing the nucleic acid sequences; and methods for the production of the aforementioned materials.Type: GrantFiled: October 30, 2017Date of Patent: February 18, 2020Assignee: FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC.Inventors: Eric Holmes, Gary Ostrander
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Patent number: 10566116Abstract: A series of solid solutions AlFe2_xMnxB2 have been synthesized by arc-melting and characterized by powder X-ray diffraction, and magnetic measurements. All the compounds adopt the parent AlFe2B2-type structure, in which infinite zigzag chains of B atoms are connected by Fe atoms into [Fe2B2] slabs that alternate with layers of Al atoms along the b axis. The parent AlFe2B2 is a ferromagnet with Tc=282 K. A systematic investigation of solid solutions AlFe2_xMnx.B2 showed a non-linear change in the structural and magnetic behavior. The ferromagnetic ordering temperature is gradually decreased as the Mn content (x) increases. The substitution of Mn for Fe offers a convenient method for the adjustment of the ferromagnetic ordering temperature of AlFe2B2.Type: GrantFiled: January 8, 2016Date of Patent: February 18, 2020Assignee: The Florida State University Research Foundation, Inc.Inventors: Michael Shatruk, Xiaoyan Tan, Ping Chai
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Patent number: 10567057Abstract: A method for performing, by a UE, channel estimation in a wireless communication system includes: receiving, from an eNB, a control message including reference signal transmission pattern information representing a transmission pattern of a channel estimation reference signal (RS) transmitted through antenna ports; receiving the reference signal from the eNB on the basis of the received reference signal transmission pattern information; measuring a channel per antenna port of the eNB on the basis of the received reference signal; and feeding back channel state information related to the measured channel to the eNB.Type: GrantFiled: December 18, 2015Date of Patent: February 18, 2020Assignees: LG ELECTRONICS INC., SOGANG UNIVERSITY RESEARCH FOUNDATIONInventors: Jonghyun Park, Wonjin Sung, Yoonsoo Kim, Kijun Kim
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Patent number: 10561642Abstract: The present invention concerns the use of castanospermine or other alpha-glucosidase inhibitors for the treatment or prevention of Zika virus infections. Aspects of the invention include methods for treating or preventing Zika virus infection by administering an alpha-glucosidase inhibitor (e.g., an alpha-glucosidase I inhibitor) to a subject in need thereof; methods for inhibiting a Zika virus infection in a cell in vitro or in vivo; pharmaceutical compositions; packaged dosage formulations; and kits for treating or preventing Zika virus infection.Type: GrantFiled: December 28, 2017Date of Patent: February 18, 2020Assignee: FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC.Inventors: Eric Holmes, Gary Ostrander
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Publication number: 20200051722Abstract: A system comprising a solenoid electromagnet for generating a magnetic field and a driver circuit coupled to the solenoid electromagnet for modulating the magnetic field generated by the solenoid electromagnet. The magnetic field generated by the solenoid electromagnet of the present invention exhibits improved control over the direction and projection of the generated magnetic field. The generated magnetic field has the ability to detach permanent magnets from metal plates, cause motion of permanent magnets and soft magnetic materials as well as create separation between two magnetically bound permanent magnets.Type: ApplicationFiled: April 23, 2018Publication date: February 13, 2020Applicant: The Florida State University Research Foundation, Inc.Inventors: Jeffrey B. WHALEN, Eric LOCHNER, Petru ANDREI, Theo SIEGRIST, Timothy P. MURPHY
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Patent number: PP31464Abstract: The new and distinct zoysiagrass variety described herein is a Z. matrella x Z. japonica F1 hybrid named ‘KSUZ 0802’. ‘KSUZ 0802’ can be distinguished by its superior turf quality, fine-textured leaves, increased resistance to bluegrass billbug (Sphenophorus parvulus Ghyllenhaal), and cold tolerance that is comparable to zoysiagrass varieties adapted to the transition zone growing region in the U.S.Type: GrantFiled: May 7, 2018Date of Patent: February 18, 2020Assignees: The Texas A&M University System, Kansas State University Research FoundationInventors: Ambika Chandra, Milton C. Engelke, Anthony D. Genovesi, Jack Fry