Abstract: Nucleic acids encoding a novel ferritin light chain variant, a ferritin light chain variant polypeptide, ferritin light chain variant polypeptide-specific antibodies, and methods of use thereof are provided herein. Also provided are methods to screen and identify agents capable of modulating the activity of the ferritin light chain variant.
Abstract: The operation of a planar geometry superconducting coil used in conjunction with a ground plane is improved by intracoil damping. This damping reduces coil resonances. The improvement consists of an intracoil shunt, which damps the resonances of the coil by connecting each turn, or loop, of the multiturn/multiloop coil with resistors. One example of a planar geometry superconducting coil which is effectively damped according to the present invention is the input coil to a superconducting quantum interference device (SQUID). The intracoil shunt may be added to the SQUID at the same time in the SQUID fabrication as the junction shunts.
Type:
Grant
Filed:
August 13, 1998
Date of Patent:
January 2, 2001
Assignees:
University Technology Corp., National Institute of Standards and Technology
Inventors:
Andrew Harvey Steinbach, Martin Emile Huber, Ronald Hajime Ono
Abstract: The present invention relates to a novel benzoquinone, 2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone and its esters. The compounds can be used to treat tumors exhibiting elevated levels of the enzyme DT-diaphorase.
Type:
Grant
Filed:
May 24, 1999
Date of Patent:
December 5, 2000
Assignees:
Cancer Research Campaign Tech (London), University Technology Corp., University of Salford
Inventors:
David Ross, John Butler, Robert H. J. Hargreaves, David Siegel, Howard D. Beall
Abstract: A modified zeolite or molecular sieve membrane for separation of materials on a molecular scale. The modified membrane is fabricated to wholly or partially block regions between zeolite crystals to inhibit transfer of larger molecules through the membrane, but without blocking or substantially inhibiting transfer of small molecules through pores in the crystalline structure. The modified membrane has a monomolecular layer deposited on the zeolite surface which has coordinated groups of atoms that include (i) a metal atom bonded to oxygen atoms that are bonded to the zeolite substrate atoms (e.g., silicon atoms) and (ii) either hydroxyl groups bonded to the metal atoms or additional oxygen atoms bonded to the metal atoms.
Type:
Grant
Filed:
January 26, 1999
Date of Patent:
April 18, 2000
Assignee:
University Technology Corp.
Inventors:
Hans H. Funke, Jason W. Klaus, Steven M. George, Andrew W. Ott, John L. Falconer, Richard D. Noble
Abstract: A display includes a plurality of individually electrically controllable pixels. Each pixel has a layer of light controlling medium extending over a predetermined area of the pixel. The light controlling medium is responsive to electrical fields directed through the area of the light controlling medium for controlling the light passing through the pixel as a predetermined function of the magnitude of the electric field. Each pixel has an electric field directing arrangement for directing an electric field through the layer of light controlling medium of the pixel. The electric field for each pixel is controllably variable over the area of the light controlling medium of the pixel such that the light passing through the area of the light controlling medium of the pixel is controlled in a manner that varies over the area of the pixel depending on the variable electric field.
Abstract: The present invention provides for the regulation of the rate of a chemical reaction within the aqueous micelles within a microemulsion of water in supercritical carbon dioxide. Increase in pressure increases the concentration of an ionized reaction component (reactant, catalyst or reaction initiator) within the reverse micelles, thus increasing the rate of the reaction or allowing the reaction to initiate. Similarly, the reaction rate can be slowed by decreasing the pressure, thus decreasing the amount of water and ionized components in the reverse micelles. Decrease in the pressure below a critical level results in the reaction stopping when the concentration of a ionized reaction component falls to a sufficiently low level.