Abstract: The systems, methods and associated devices electronically collect, report and generate normalized educational outcome summaries of multiple different educational inputs, including didactic, experiential and problem solving events and/or assessments.
Abstract: Provided is a physical layer blind authentication method for a time-varying fading channel based on a smoothing technique. The method includes that: a transmitter transmits a carrier signal to a wireless channel, the carrier signal includes an authentication signal, a pilot signal and an information signal, and the wireless channel is the time-varying fading channel; a receiver receives the carrier signal, and performs BKIC processing and differential signal processing on the carrier signal to obtain a target authentication signal, performs the differential signal processing on the reference signal to obtain a reference authentication signal, and calculates a correlation between the target authentication signal and the reference authentication signal to obtain a test statistic; and compares the test statistic with a prescribed threshold to determine whether the carrier signal is capable of passing authentication.
Abstract: Methods and systems for building and maintaining model(s) of a physical process are disclosed. One method includes receiving training data associated with a plurality of different data sources, and performing a clustering process to form one or more clusters. For each of the one or more clusters, the method includes building a data model based on the training data associated with the data sources in the cluster, automatically performing a data cleansing process on operational data based on the data model, and automatically updating the data model based on updated training data that is received as operational data. For data sources excluded from the clusters, automatic building, data cleansing, and updating of models can also be applied.
Type:
Grant
Filed:
May 1, 2020
Date of Patent:
November 22, 2022
Assignees:
Chevron U.S.A. Inc., University of Southern California
Inventors:
Yining Dong, Alisha Deshpande, Yingying Zheng, Lisa Ann Brenskelle, Si-Zhao Qin
Abstract: In one aspect, the invention relates to a method of loading exosomes with oligonucleotide cargo, by incubating an oligonucleotide comprising one or more hydrophobic modifications with a population of exosomes for a period of time sufficient to allow loading of the exosomes with the oligonucleotide. Exosomes loaded with hydrophobically modified oligonucleotide cargo, and uses thereof, are also provided.
Type:
Grant
Filed:
December 13, 2019
Date of Patent:
November 22, 2022
Assignee:
University of Massachusetts
Inventors:
Anastasia Khvorova, Neil Aronin, Marie Cecile Didiot, Reka Haraszti
Abstract: Described herein is a process for preparing inorganic metal-containing films including bringing a solid substrate in contact with a compound of general formula (I) or (II) in the gaseous state where A is NR2 or OR with R being an alkyl group, an alkenyl group, an aryl group, or a silyl group, E is NR or O, n is 1, 2 or 3, and R? is hydrogen, an alkyl group, an alkenyl group, an aryl group, or a silyl group, wherein if n is 2 and E is NR or A is OR, at least one R in NR or OR bears no hydrogen atom in the 1-position.
Type:
Grant
Filed:
November 9, 2018
Date of Patent:
November 22, 2022
Assignees:
BASF SE, Wayne State University
Inventors:
Lukas Mayr, David Dominique Schweinfurth, Daniel Waldmann, Charles Hartger Winter, Kyle Blakeney, Sinja Verena Klenk, Sabine Weiguny, Nilanka Weerathunga Sirikkathuge, Tharindu Malawara Arachchige Nimanthaka Karunaratne
Abstract: A method for producing a transition metal dichalcogenide-graphene heterojunction composite, the method includes: transferring a graphene onto a flexile substrate; depositing a transition metal layer on the flexible substrate onto which the graphene has been transferred; and injecting a gas containing plasma-treated sulfur (S) onto the flexile substrate onto which the transition metal layer has been deposited, is disclosed.
Type:
Grant
Filed:
May 25, 2021
Date of Patent:
November 22, 2022
Assignees:
Research & Business Foundation Sungkyunkwan University, Ajou University Industry-Academic Cooperation Foundation
Inventors:
Taesung Kim, Jaehyun Lee, Hyunho Seok, Hyeong U Kim
Abstract: An Nth order linear differential microphone array (LDMA) with a steerable beamformer may be constructed by specifying a target beampattern for the LDMA at a steering angle ?. An Nth order polynomial associated with the target beampattern may then be generated. A relationship between the nulls of the polynomial and the steering angle ? is determined and then a value of one of the nulls is determined based on N?1 assigned values for the other nulls and the determined relationship between the nulls of the polynomial and the steering angle ?. The steerable beamformer may be generated based on the determined null value and the N?1 assigned null values. The N?1 assigned null values may be associated with the N?1 nulls of the polynomial that are of less than Nth order and the determined null value may be associated with the null of the polynomial that is of Nth order.
Type:
Grant
Filed:
March 3, 2021
Date of Patent:
November 22, 2022
Assignee:
Northwestern Polytechnical University
Inventors:
Jingdong Chen, Jilu Jin, Gongping Huang, Xuehan Wang
Abstract: An inventive concept relates to an audio coding method to which CNN-based frequency spectrum recovery is applied. An inventive concept transmits a part of frequency spectral coefficients generated in transform coding to a decoder and the decoder recovers the frequency spectral coefficient not transmitted. Furthermore, the signs of frequency spectral coefficient are transmitted from an encoder to the decoder depending on a sign transmission rule.
Type:
Grant
Filed:
April 8, 2020
Date of Patent:
November 22, 2022
Assignees:
Electronics and Telecommunications Research Institute, Kwangwoon University Industry-Academic Collaboration Foundation
Inventors:
Hochong Park, Seung Kwon Beack, Jongmo Sung, Seong-Hyeon Shin, Mi Suk Lee, Tae Jin Lee, Jin Soo Choi
Abstract: Systems and methods for providing a combined mosquito staging and dissection system are disclosed. The system can include a mosquito staging subsystem; a robotic pick-and-place station; and a dissection, extrusion, collection, and disposal subsystem. The subsystems can include one or more stations to provide orientation, decapitation, extrusion of salivary glands, and disposal of carcasses of the mosquitoes. The resident live sporozoites from the salivary glands can be used to produce Plasmodium SPZ-based vaccines.
Type:
Grant
Filed:
August 17, 2020
Date of Patent:
November 22, 2022
Assignees:
Sanaria Inc., The Johns Hopkins University
Inventors:
Russell H. Taylor, Gregory Chirikjian, Iulian Iordachita, Henry Phalen, Hongtao Wu, Mengdi Xu, Shengnan Lu, Michael Aaron Pozin, Jin Seob Kim, Can Kocabalkanli, Balazs Vagvolgyi, Brian K. Chirikjian, Joshua Davis, Ting Da, John S. Chirikjian, Sumana Chakravarty, Stephen Hoffman
Abstract: A method for treating autoimmune and/or inflammatory disease includes a step of identifying a subject exhibiting symptoms of autoimmune and/or inflammatory disease administering a fasting mimicking diet. A probiotic composition for gastrointestinal autoimmune and/or inflammatory disease Bacteroides acidifaciens, Bifidobacterium choerinum, and combinations thereof is also provided.
Abstract: A method of making a hydrodesulfurization catalyst having nickel and molybdenum sulfides deposited on a support material containing mesoporous silica that is optionally modified with zirconium. The method of making the hydrodesulfurization catalyst involves a single-step calcination and reduction procedure. The utilization of the hydrodesulfurization catalyst in treating a hydrocarbon feedstock containing sulfur compounds (e.g. dibenzothiophene, 4,6-dimethyldibenzothiophene) to produce a desulfurized hydrocarbon stream is also provided.
Type:
Grant
Filed:
June 27, 2019
Date of Patent:
November 22, 2022
Assignee:
King Fahd University of Petroleum and Minerals
Inventors:
Khalid R. Alhooshani, Saheed Adewale Ganiyu
Abstract: A multi-layer vector-matrix multiplication (VMM) apparatus is provided. The multi-layer VMM apparatus includes a three-dimensional (3D) NAND flash structure having multiple transistor array layers each includes a number of transistors configured to store a respective weight matrix and a number of word lines configured to receive respective selection voltages corresponding to a respective input vector. Accordingly, each of the transistor array layers can perform a respective VMM operation by multiplying the respective selection voltages with the respective weight matrix. Thus, by providing the respective selection voltages to each of the multiple transistor array layers in a sequential order, it may be possible to carry out a multi-layer VMM operation in the 3D NAND flash structure with reduced footprint, thus making it possible to support a deep neural network (DNN) via such advanced techniques as in-memory computing.
Type:
Grant
Filed:
May 2, 2019
Date of Patent:
November 22, 2022
Assignee:
Arizona Board of Regents on behalf of Arizona State University
Abstract: The invention provides methods for preparing DNA sequencing libraries by assembling short read sequencing data into longer contiguous sequences for genome assembly, full length cDNA sequencing, metagenomics, and the analysis of repetitive sequences of assembled genomes.
Type:
Grant
Filed:
February 28, 2020
Date of Patent:
November 22, 2022
Assignee:
University of Washington
Inventors:
Jay Shendure, Joseph Hiatt, Rupali Patwardhan, Emily Turner
Abstract: An image encoding/decoding method using a pixel value range constituting an image is disclosed, wherein the image decoding method using a pixel value range constituting an image comprises the steps of: receiving a bitstream; acquiring information of a pixel value range forming a first unit image included in the received bitstream; and decoding the first unit image on the basis of the acquired information of the pixel value range. Therefore, compression efficiency can be improved in an image encoding or decoding process.
Type:
Grant
Filed:
March 12, 2021
Date of Patent:
November 22, 2022
Assignee:
Industry-University Cooperation Foundation Hanyang University
Abstract: A use of an anthranilic acid derivative as a matrix for a MALDI Mass spectrometry, comprising: preparing a matrix compound represented by the following formula: wherein X is selected from hydrogen and a hydroxyl group, and Y is selected from hydrogen, a methyl group or an acetyl group, provided that when X is hydrogen, Y is hydrogen or an acetyl group, and when X is a hydroxyl group, Y is a methyl group; applying the matrix compound and an analyte onto a sample holder; and analyzing the analyte by the MALDI mass spectrometer.
Abstract: The present invention provides a method and apparatus for tissue, such as an allograft, storage and preservation for extended periods of time at room temperature in a sterile tissue culture chamber. The invention further provides a process for maintaining the sterility of tissue using the apparatus as described.
Type:
Grant
Filed:
September 5, 2019
Date of Patent:
November 22, 2022
Assignees:
The Curators of the University of Missouri, The Trustees of Columbia University
Inventors:
James L. Cook, Clark T. Hung, Eric Lima, Aaron Stoker
Abstract: The present disclosure is directed to compositions and methods to treat the inflammatory response present in certain diseases and illnesses by modifying a dysregulation of one or more genes associated with the Wnt/?-catenin signaling pathway. Embodiments of the disclosure can provide methods for treating an inflammatory response in a patient by identifying the inflammatory response and modifying the inflammatory response.
Abstract: Provided are methods for treating diseases, disorders, and conditions associated with undesirable cellular proliferation in subjects in need thereof. In some embodiments, the methods include administering to a subject in need thereof a therapeutically effective amount of a composition comprising, consisting essentially of, or consisting of a chemotherapeutic agent and a short chain ceramide. Also provided are methods for increasing total ceramide levels in cells, for increasing long chain ceramide to a very long chain ceramide ratios in cells, methods for enhancing apoptosis of cells, for prognosing subjects with diseases, disorders, and conditions associated with undesirable cellular proliferation with respect to treatments, for increasing sensitivities of drug-resistant tumor and/or cancer cells to chemotherapeutics, and compositions that have one or more short chain ceramides and one or more chemotherapeutically active agents.
Type:
Application
Filed:
October 16, 2020
Publication date:
November 17, 2022
Applicant:
University of Virginia Patent Foundation
Inventors:
Mark Kester, Tye Deering, Thomas P. Loughran, JR., Todd E. Fox, Pedro Filipe Da Costa Pinheiro, David J. Feith
Abstract: Pharmaceutical compositions comprising a selective TGF-? inhibitor, such as a TGF?RII-Fc, are provided herein to prevent, reverse, reduce the occurrence of and/or treat fatty degeneration of skeletal muscle. Additionally, the selective TGF-? inhibitors may be used to inhibit fibro-adipogenic progenitor cell (FAP) differentiation into adipocytes.
Type:
Application
Filed:
July 22, 2020
Publication date:
November 17, 2022
Applicant:
Board of Trustees of Michigan State University