Abstract: A Micro-Well Array Plates (MWAP) assembly for high throughput microfluidic devices for studying cells and method of manufacturing thereof are provided. The MWAP assembly includes a top plate having a plurality of macro-wells arranged in an array within a frame. The MWAP assembly also includes a bottom plate operable to be secured to the bottom surface of the frame, the bottom plate having a plurality of arrays of micro-wells. The MWAP assembly includes a well grid formed when the bottom plate is secured to the top plate via the plurality of macro-wells and the plurality of arrays micro-wells. The well grid with the plurality of macro-wells and the plurality of arrays micro-wells enable visualization of cells via a high throughput.
Type:
Application
Filed:
October 22, 2021
Publication date:
December 21, 2023
Applicant:
The Board of Regents of The University of Texas System
Abstract: In a method, an electrode layer and an insulation layer are alternately and repeatedly stacked on a substrate. A first insulation layer is etched through a first dry etching process using an etching gas including fluorine to form an opening exposing a first electrode layer. The first electrode layer exposed by the opening is partially removed through an RIE process using oxygen and/or hydrogen plasma to enlarge the opening so that a second insulation layer is exposed. The second insulation layer exposed by the opening is etched through a second dry etching process using an etching gas including fluorine to enlarge the opening so that a second electrode layer is exposed. A contact plug is formed in the enlarged opening.
Type:
Application
Filed:
May 11, 2023
Publication date:
December 21, 2023
Applicant:
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
Inventors:
Minsik KIM, Gwanhyoung LEE, Sukhoon KIM, Yongjun SHIN
Abstract: A recyclable polyurethane foam is produced by reacting a carbon dioxide-based polyol-containing composition and an isocyanate composition. The polyurethane foam may include a molar ratio of active hydrogen to isocyanate groups of 1:0.9. The polyurethane foam may include a catalyst at about greater than or equal to about 0.5 to less than or equal to about 1.5 parts by weight percent.
Type:
Application
Filed:
June 21, 2022
Publication date:
December 21, 2023
Applicants:
Ford Motor Company, Washington State University
Abstract: The present disclosure provides a Paenibacillus mucilaginosus LT1906 and use thereof, and a microorganism-activated circulating fluidized bed (CFB) fly ash-based cementitious material and a preparation method and use thereof, belonging to the technical field of cementitious materials. The Paenibacillus mucilaginosus LT1906 has a deposit number of CGMCC No. 21337. The strain is capable of dissolving silicate minerals and aluminosilicate minerals in the CFB fly ash to increase dissolution of active SiO2. The strain is used for activating the CFB fly ash-based cementitious material, to ameliorate a large water demand and a low early strength of the cementitious material, thereby improving comprehensive utilization of the CFB fly ash in the field of building materials.
Abstract: The present invention relates to a platinum-based sputtering target containing platinum or a platinum alloy. The platinum-based sputtering target of the present invention is characterized by a material structure in a thickness-direction cross section thereof. Specifically, when a thickness-direction cross section is equally divided into n sections (n=5 to 20) along a thickness direction, a region including (n?2) sections excluding both end sections is set as a determination region, and when an average grain size in each of the sections is measured in the determination region, as well as an average grain size in the entire determination region is measured, the average grain size in the entire determination region is 150 ?m or less, and a coefficient of variation calculated based on the average grain size in each of the sections of the determination region is 15% or less.
Abstract: A method for extracting a kansei adjective of a product based on principal component analysis and explanation (PCA-E) includes constructing a product kansei evaluation vector matrix through original kansei adjectives; performing dimensionality reduction through PCA; and determining, based on principal component load factors, kansei adjectives representing principal components. In this way, the kansei adjectives extracted are explanatory to help users understand the selected kansei adjectives and make accurate evaluation.
Type:
Application
Filed:
June 2, 2023
Publication date:
December 21, 2023
Applicant:
SICHUAN UNIVERSITY
Inventors:
Wu ZHAO, Xin GUO, Miao YU, Kai ZHANG, Wei JIANG, Chong JIANG, Bing LAI, Yiwei JIANG, Jun LI, Bo WU, Xingyu CHEN
Abstract: Disclosed herein is an electrochemical biosensor comprising at least one working electrode on an electrically insulative substrate. At least one working electrode incorporates an electrocatalytic film, comprising a molecularly imprinted polymer (MIP) layer. In at least one embodiment, MIP layer comprises a plurality of shape-selective cavities and a plurality of non-biological electrocatalytic centers.
Abstract: Disclosed herein is a spatially decoupled redox flow water electrolyzer, that has a hydrogen-producing catholyte section formed from a catholyte tank, having a cathode, and a hydrogen generation compartment, where the catholyte tank and the hydrogen generation compartment are fluidly connected to one another by a fluid pathway, so as to facilitate the circulation of a liquid catholyte from the catholyte tank to the hydrogen generation compartment and back to the catholyte tank and an oxygen-producing anolyte section formed from an anolyte tank, having an anode, and an oxygen producing compartment, where the anolyte tank and the oxygen producing compartment are fluidly connected to one another by a fluid pathway, so as to facilitate the circulation of a liquid anolyte from the anolyte tank to the oxygen producing compartment and back to the anolyte tank, an anion-exchange membrane is disposed between the catholyte and anolyte tanks and a current collector attached to the catholyte and anolyte tanks.
Abstract: A damping device includes a superelastic element made of an austenitic shape memory alloy and an energy-absorbing element adjacent to the superelastic element, wherein the energy-absorbing element is made of a material selected from a shape memory alloy, a malleable metal or alloy, and a viscoelastic polymer, and wherein deformation of the energy-absorbing element is restrained by the superelastic element.
Type:
Application
Filed:
September 24, 2021
Publication date:
December 21, 2023
Applicant:
William Marsh Rice University
Inventors:
Darel Hodgson, Mohammad Salehi, Reginald Desroches
Abstract: A conductive paste composition includes: carbon black having a porous structure and having a DBP oil absorption amount of greater than 240 mL/100 g and a specific surface area of greater than 350 m2/g; and a liquid silicone rubber base composition, in which in a case where the conductive paste composition is dried and cured at 180° C. for two hours to form a conductive film, a content of the carbon black in the conductive film is 4% by mass or greater and 24% by mass or less, and a surface resistance of the conductive film is 1 k? or greater and 9 k? or less.
Type:
Application
Filed:
October 15, 2021
Publication date:
December 21, 2023
Applicants:
Lion Specialty Chemicals Co., Ltd., University of Hyogo
Abstract: A method for efficiently purifying and detecting 6-hydroxynobilonine in fresh stems of dendrobium huoshanense uses a gas chromatography-mass spectrometry (GC-MS) method to detect 6-hydroxynobilonine in dendrobium huoshanense is, i.e.
Type:
Application
Filed:
June 21, 2023
Publication date:
December 21, 2023
Applicant:
Anhui Agricultural University
Inventors:
Xianfeng DU, Yuchen GAO, Li LIN, Yaoyao XIA
Abstract: Formaldehyde is obtained from CO2 through hydrogenation of CO2 to methanol while the subsequent oxidation of methanol yields formaldehyde. This formaldehyde combined with the electrochemically produced glycolaldehyde generates sugars, thus establishing a route from CO2 to sugars.
Type:
Application
Filed:
August 30, 2023
Publication date:
December 21, 2023
Applicant:
The Regents of the University of California
Inventors:
Peidong Yang, Stefano Cestellos-Blanco, Yifan Li, Michael B. Ross
Abstract: A system and method for mechanical processing of cells includes using a frame (102) forming an inlet channel (104), an outlet channel (106), and a processing chamber (108) fluidly connected between the inlet and outlet channels, wherein the processing chamber includes an anvil surface (112) formed on the frame. A hammer (110) mounted on the frame has a processing surface disposed in opposed relation to the anvil surface. The hammer is configured to move relative to the anvil surface. An actuator connected to the frame and operably associated with the hammer operates to move the hammer relative to the anvil surface and in close proximity to the anvil surface, wherein the hammer operates between a retracted position in which the processing surface is at a distance from the anvil surface, and an extended position in which the processing surface abuts the anvil surface.
Type:
Application
Filed:
November 9, 2021
Publication date:
December 21, 2023
Applicants:
The University of Chicago, UChicago Argonne, LLC
Abstract: Systems and methods for automated diagnosis and prognosis support using radiomics in accordance with embodiments of the invention are illustrated. One embodiment includes a method for non-invasively identifying triple negative breast cancer, comprising obtaining a magnetic resonance imaging scan of a patient's breast, generating a tumor segmentation mask for the scan of the patient using a first machine learning model, extracting several radiomic features from the segmented scan of the patient, providing the several radiomic features to a second machine learning model, and obtaining, from the second machine learning model, a likelihood that the patient has triple negative breast cancer. In a further embodiment, the second machine learning model further provides an estimated survival time of the patient.
Type:
Application
Filed:
May 23, 2023
Publication date:
December 21, 2023
Applicant:
The Board of Trustees of the Leland Stanford Junior University
Abstract: The present invention relates to improved complexes of amorphous calcium phosphate and/or amorphous calcium fluoride phosphate stabilised by phosphopeptides/phosphoproteins by addition of stannous ions. These complexes have anticariogenic properties useful to protect tooth structures as they remineralize (repair) early stages of dental caries and have other dental/medical applications (including anti-calculus, anti-erosion/corrosion and anti-dentinal hypersensitivity). Methods of making the complexes of the invention and of treatment or prevention of various dental conditions including dental caries, dental calculus, dental erosion/corrosion and dental hypersensitivity are also provided.
Abstract: Systems and methods for optical computation and acousto-optic modulation are described. The systems and methods comprise acousto-optic modulators with reflectors and transducers used for actuation and modulation of mechanical waves. The systems further comprise multilayer optical computing systems incorporating arrays of acousto-optic modulators.
Abstract: Systems and methods for energy storage and energy recovery are provided. An electrical-to-electrical energy storage system includes a thermochemical energy storage device, a blower, a compressor, a turbine, and an electrical generator. The TCES device includes a vessel, a porous bed, and a heater. The porous bed is disposed within an interior volume of the vessel. The porous bed comprises a reactive material. The reactive material is configured to release oxygen upon being heated to a reduction temperature, and generate heat when exposed to oxygen. The heater is in thermal contact with the reactive material. The blower is configured to remove oxygen from the interior volume. The compressor is configured to flow oxygen into the interior volume. The turbine is configured to receive a heated, oxygen-depleted gas from the interior volume. The generator is configured to be powered by the turbine to generate electricity.
Type:
Application
Filed:
August 28, 2023
Publication date:
December 21, 2023
Applicant:
Board of Trustees of Michigan State University
Inventors:
James F. KLAUSNER, Joerg PETRASCH, Kelvin RANDHIR, Nima RAHMATIAN
Abstract: An apparatus includes a rotating pole, a first set of photovoltaic modules; and a second set of photovoltaic modules. The second set of photovoltaic modules do not rotate with the rotating pole.
Type:
Application
Filed:
June 24, 2023
Publication date:
December 21, 2023
Applicant:
Abu Dhabi University
Inventors:
Anas I.Q. Al Tarabsheh, Mohammad A. Ghazal
Abstract: A method for reducing pulmonary hypertension in a mammal that employs FK506 is provided. In certain embodiments, the method comprises administering FK506 to a mammal having pulmonary arterial hypertension associated with defective MBPR2 signaling at a dosage sufficient to reduce blood pressure in the pulmonary artery of the mammal.
Type:
Application
Filed:
January 6, 2023
Publication date:
December 21, 2023
Applicant:
The Board of Trustees of the Leland Stanford Junior University
Inventors:
Edda SPIEKERKOETTER, Marlene RABINOVITCH, Philip A. BEACHY, David SOLOW-CORDERO
Abstract: The present invention relates to an application of an isoquinoline compound in tumor treatment. Specifically, the present invention provides a use of a compound of formula I, or an optical isomer or a racemate thereof, or a solvate thereof, or a pharmaceutically acceptable salt thereof used for the preparation of a composition or formulation for the prevention and/or treatment of a tumor. The compound of the present invention has significant and exceptional therapeutic effects on tumors with low or no expression of an NNMT gene, high expression of a DNA methylase, high expression of UHRF1, high methylation levels at an NNMT gene nucleotide site, and/or high methylation levels at a DNA CpG site in an NNMT gene region.
Type:
Application
Filed:
November 5, 2021
Publication date:
December 21, 2023
Applicants:
NANJIANG SHIJIANG MEDICINE TECHNOLOGY CO., LTD, TONGJI UNIVERSITY