Patents Assigned to University
  • Publication number: 20220334102
    Abstract: The present invention provides an ex vivo lymph node is provided. The ex vivo lymph node comprises an intact lobule in a chamber connected to an afferent lymphatic vessel and an efferent lymphatic vessel. The intact lobule is perfused with a lymphatic fluid into the chamber via the afferent lymphatic vessel and out of the chamber via the efferent lymphatic vessel and perfused with a vascular fluid into the intact lobule via an endogenous artery and out of the intact lobule via an endogenous vein. Also provided is a method for preparing the ex vivo lymph node. Further provided are methods for screening for an agent capable of changing the ex vivo lymph node, producing T lymphocytes or B lymphocytes and determining immunoreactivity of the ex vivo lymph node.
    Type: Application
    Filed: September 16, 2020
    Publication date: October 20, 2022
    Applicant: University of Delaware
    Inventors: Jason Paul Gleghorn, Ryan Mark Zurakowski
  • Publication number: 20220337816
    Abstract: An image decoding method and an image decoding apparatus is provided. The method comprises recovering a first motion vector corresponding to a first decoding reference picture based on the entropy decoded bit stream, calculating a second motion vector corresponding to a second decoding reference picture by scaling the first motion vector based on a first temporal distance between the current picture and the first decoding reference picture and a second temporal distance between the current picture and the second decoding reference picture, generating a prediction block relating to a current block in the current picture, based on the calculated second motion vector, generating a residual block relating to the current block through a residual data decoding process based on the entropy decoded bit stream, and recovering the current block based on the prediction block and the residual block.
    Type: Application
    Filed: June 27, 2022
    Publication date: October 20, 2022
    Applicant: SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION
    Inventors: Byeung Woo JEON, Bong Soo JUNG, Kwang Hyun WON
  • Publication number: 20220330939
    Abstract: A medical device includes a surgical needle attached to a hollow tubular suture. The suture is constructed of macroporous hollow tubular wall that facilitates and allows tissue integration into the suture core subsequent to introduction to the body, thereby preventing suture pull-through and improving biocompatibility.
    Type: Application
    Filed: April 1, 2022
    Publication date: October 20, 2022
    Applicant: Northwestern University
    Inventors: Gregory Dumanian, Anandev Gurjala
  • Publication number: 20220334114
    Abstract: A system for detecting COVID-19 infection, including a colorimetric sensor, an image-capturing device, and a processing unit connected to the image-capturing device. The colorimetric sensor includes an injection zone and a detection zone patterned on a paper, where the injection zone covers the detection zone by folding the paper. The injection zone is configured to inject a saliva sample acquired from a person thereon. The detection zone includes an array of chemical receptors configured to interact with the injected saliva penetrating into the detection zone. The processing unit is configured to perform a method of capturing a first image from the detection zone before injection of the saliva sample, capturing a second image from the detection zone after injection of the saliva sample, and detecting COVID-19 infection status of the person by analyzing color changes of the array of chemical receptors in the second image respective to the first image.
    Type: Application
    Filed: June 27, 2022
    Publication date: October 20, 2022
    Applicants: Farin Behbood Tashkhis Company, Bagiyatallah University of Medical Sciences - Chemical Injuries Research Center
    Inventors: Hasan Bagheri, Mohammad Mahdi Bordbar, Hosein Khoshsafar, Pegah Hashemi, Mostafa Ghanei
  • Publication number: 20220333158
    Abstract: Methods of uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are provided. Kits for uniquely labeling or barcoding molecules within a cell, a plurality of cells, and/or a tissue are also provided. The molecules to be labeled may include, but are not limited to, RNAs, cDNAs, DNAs, proteins, peptides, and/or antigens.
    Type: Application
    Filed: March 15, 2022
    Publication date: October 20, 2022
    Applicant: University of Washington
    Inventors: Georg Seelig, Richard Muscat, Alexander B. Rosenberg
  • Publication number: 20220336058
    Abstract: The invention relates to methods for multiplex tissue imaging by methods such as imaging mass cytometry (IMC) and methods for analysis of imaging mass cytometry data. In various embodiments, methods are provided of cell-of-origin analysis and mutational analysis, coupled with spatial parameters derived from tumor clusters in the tumor microenvironment; which reveals signature marker profiles and therapeutic targets for treating cancers including diffuse large B cell lymphoma.
    Type: Application
    Filed: September 25, 2020
    Publication date: October 20, 2022
    Applicants: CEDARS-SINAI MEDICAL CENTER, UNIVERSITY OF SOUTHERN CALIFORNIA
    Inventors: Akil Merchant, Anthony Colombo, Monirath Hav
  • Publication number: 20220334034
    Abstract: Miniaturized solid-phase extraction (SPE) systems and processes are disclosed. The systems and methods enable preconcentration methods for sample preparation that can be performed on a variety of specimens. The miniaturization of SPE system is accomplished with 3D-printed microfluidic device for fast and simple extraction of analytes.
    Type: Application
    Filed: April 7, 2022
    Publication date: October 20, 2022
    Applicant: Brigham Young University
    Inventors: Adam T. WOOLLEY, Anna V. BICKHAM, Gregory P. NORDIN
  • Publication number: 20220332025
    Abstract: A composition containing a melt-moldable fluororesin having a 1% decomposition temperature of 300° C. or higher and a thermotropic liquid crystal polymer, 90 mol % or more of all repeating units of the thermotropic liquid crystal polymer having an aromatic structure. The fluororesin is contained in an amount of 99.99 to 97% by mass and the thermotropic liquid crystal polymer is contained in an amount of 0.01 to 3% by mass relative to the composition. Also disclosed is an injection-molded article and a molding aid for injection molding fluororesin.
    Type: Application
    Filed: June 23, 2022
    Publication date: October 20, 2022
    Applicants: DAIKIN INDUSTRIES, LTD., TSINGHUA UNIVERSITY
    Inventors: Xuming XIE, Yuki UEDA, Masaji KOMORI, Akiyoshi YAMAUCHI
  • Publication number: 20220331368
    Abstract: The present invention relates to a pharmaceutical composition comprising glia-like cells differentiated from human mesenchymal stem cells as an active ingredient for treatment of stroke. Specifically, as a result of injecting the glia-like cells differentiated from human mesenchymal stem cells (ghMSCs) of the present invention to cerebral infarction-induced animal models, the infarct volume remarkably decreased by 50% or more and neural functions were remarkably improved, compared to a control group and a group treated with human mesenchymal stem cells (hMSCs), demonstrating that ischemic stroke (infarction) is treated by the Akt pathway of IGFBP-4 via IGF-1R. Thus, the differentiated glia-like cells of the present invention can be advantageously used as a cell therapy product for stroke.
    Type: Application
    Filed: August 24, 2020
    Publication date: October 20, 2022
    Applicants: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION, IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY)
    Inventors: Mi-Sook Chang, Seong-Ho Koh
  • Publication number: 20220331746
    Abstract: Disclosed are a light-driven filtration antibacterial composite membrane and a preparation method and use thereof. The method for preparing the light-driven filtration antibacterial composite membrane includes: mixing dichloromethane and N,N-dimethylformamide to obtain a first solution; adding PCL particles to the first solution, and stirring until being uniform to obtain an electrospinning solution; adding a ZIF-8 powder to the electrospinning solution, and ultrasonically dispersing for at least 1 hour to obtain a PCL/ZIF-8 spinning solution; spraying the PCL/ZIF-8 spinning solution onto a PPCL@PDA/TAEG men-blown membrane to obtain the light-driven filtration antibacterial composite membrane.
    Type: Application
    Filed: April 18, 2022
    Publication date: October 20, 2022
    Applicants: Tiangong University, Minjiang University, Tianjin Yuzhan International Trade Co., Ltd.
    Inventors: Ting-Ting LI, Lu Yang, Heng Zhang, Bo Gao, Jia-Horng Lin, Ching-Wen Lou
  • Publication number: 20220332873
    Abstract: A quaternary ammonium group-grafted cation resin and a preparation method thereof are provided. The preparation method includes: adding a chloromethylated cross-linked polystyrene (PS) resin, trimethylamine hydrochloride, and a 20% sodium hydroxide aqueous solution successively to a reactor for a reaction under stirring at 30° C. to 40° C.; filtering a resulting reaction solution, followed by washing and drying to obtain a quaternary ammonium group-grafted resin; adding the quaternary ammonium group-grafted resin, 1,2-dichloroethane, silver sulfate, concentrated sulfuric acid, and fuming sulfuric acid successively for a reaction for 1 hour at 50° C. to 60° C., a reaction for 1 hour at 70° C. to 80° C., and a reaction for 5 hours at 115° C. to 125° C.; and cooling a resulting reaction solution to room temperature, followed by diluting, filtering, washing and drying to obtain the quaternary ammonium group-grafted cation resin.
    Type: Application
    Filed: March 1, 2021
    Publication date: October 20, 2022
    Applicant: ZHEJIANG UNIVERSITY
    Inventors: Xueming CHEN, Xuejiao ZHANG
  • Publication number: 20220332592
    Abstract: Disclosed herein are amine functionalized zeolites and methods for making amine functionalized zeolites. In one or more embodiments disclosed herein, an amine functionalized zeolite may include a microporous framework including a plurality of micropores having diameters of less than or equal to 2 nm. The microporous framework may include at least silicon atoms and oxygen atoms. The amine functionalized zeolite may further include a plurality of mesopores having diameters of greater than 2 nm and less than or equal to 50 nm and one or more of isolated terminal primary amine functionalities bonded to silicon atoms of the microporous framework or silazane functionalities, where the nitrogen atom of the silazane bridges two silicon atoms of the microporous framework.
    Type: Application
    Filed: April 14, 2021
    Publication date: October 20, 2022
    Applicants: Saudi Arabian Oil Company, King Abdullah University of Science and Technology
    Inventors: Robert Peter Hodgkins, Omer Refa Koseoglu, Jean-Marie Maurice Basset, Kue-Wei Huang, Anissa Bendjeriou Sedjerari, Sathiyamoorthy Murugesan, Rajesh Parsapur
  • Publication number: 20220335170
    Abstract: A method is provided for fitting a curved surface model in a three-dimensional space to a plurality of object points in the three-dimensional space by causing a computer to perform free-form deformation (FFD). Embodiments include the steps of setting closest points corresponding to measurement points on a curved surface model, determining the movement amounts of control points by executing a least squares method to minimize the sum of squares of the distances between the closest points and the measurement points, and fitting the curved surface model to the measurement points by executing FFD based on the movement amounts.
    Type: Application
    Filed: August 24, 2020
    Publication date: October 20, 2022
    Applicants: MAZDA MOTOR CORPORATION, NATIONAL UNIVERSITY CORPORATION SHIZUOKA UNIVERSITY
    Inventors: Mataharu OKADA, Kenjiro MIURA, Yuto NAKAMURA
  • Publication number: 20220338251
    Abstract: A method for sharing a multilink in a next-generation wireless LAN is disclosed. An operation method of a first communication node comprises the steps of: setting a transmission interval; communicating with a second communication node by using a first link and a second link in the transmission interval; sharing the transmission interval with a third communication node; and communicating with the second communication node by using the first link in the transmission interval.
    Type: Application
    Filed: September 16, 2020
    Publication date: October 20, 2022
    Applicants: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE, KOREA NATIONAL UNIVERSITY OF TRANSPORTATION INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Sung Hyun HWANG, Kyu Min KANG, Jae Cheol PARK, Jin Hyung OH, Su Na CHOI, Yong Ho KIM, Yong Su GWAK
  • Patent number: 11476383
    Abstract: A device that includes a metal(III)-polar III-nitride substrate having a first surface opposite a second surface, a tunnel junction formed on one of the first surface or a buffer layer disposed on the first surface, a p-type III-nitride layer formed directly on the tunnel junction, and a number of material layers; a first material layer formed on the p-type III-nitride layer, each subsequent layer disposed on a preceding layer, where one layer from the number of material layers is patterned into a structure, that one layer being a III-nitride layer. Methods for forming the device are also disclosed.
    Type: Grant
    Filed: January 31, 2019
    Date of Patent: October 18, 2022
    Assignee: Cornell University
    Inventors: Henryk Turski, Debdeep Jena, Huili Grace Xing, Shyam Bharadwaj, Alexander Austin Chaney, Kazuki Nomoto
  • Patent number: 11476102
    Abstract: Embodiments of the present disclosure provide a real-time calibration device, a real-time calibration method and a detection apparatus. The real-time calibration device is in fluid communication with a sample injection pipeline of the apparatus to be calibrated. The real-time calibration device is configured to release a trace amount of calibration agent molecules during a sample injection of the apparatus to be calibrated, so that the trace amount of calibration agent molecules and a sample entering the apparatus to be calibrated are mixed and together enter the apparatus to be calibrated, and information of the sample and the calibration agent is detected by the apparatus to be calibrated, thereby performing a calibration.
    Type: Grant
    Filed: August 27, 2020
    Date of Patent: October 18, 2022
    Assignees: Nuctech Company Limited, Tsinghua University
    Inventors: Qingjun Zhang, Zhiqiang Chen, Yuanjing Li, Jianmin Li, Yinong Liu, Yaohong Liu, Guangqin Li, Weiping Zhu, Ge Li, Qiufeng Ma, Biao Cao
  • Patent number: 11473100
    Abstract: Isolated DNA of the Wtk1 gene or a functional equivalent capable of conferring resistance to stripe rust, is provided, as well as artificial vectors comprising same, proteins encoded by same and nucleic acid molecules for detecting same. Transgenic plants, as well as cells, seeds, and tissue therefrom which express the Wtk1 gene or a functional equivalent thereof are also provided.
    Type: Grant
    Filed: October 3, 2018
    Date of Patent: October 18, 2022
    Assignees: CARMEL HAIFA UNIVERSITY ECONOMIC CORPORATION LTD., NATURAL RESOURCES INSTITUTE FINLAND (LUKE)
    Inventors: Tzion Fahima, Abraham B. Korol, Lin Huang, Dina Raats, Valentyna Klymiuk, Zeev Frenkel, Alan Howard Schulman, Elitsur Yaniv, Andrii Fatiukha
  • Patent number: 11471444
    Abstract: Thromboxane A2 receptor antagonists, such as ifetroban, inhibit solid tumor metastasis. The formation of surface and microscopic lung metastases are inhibited. Thromboxane A2 receptor antagonists can inhibit the tumor metastasis process without affecting the growth or development of a primary tumor.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: October 18, 2022
    Assignee: Vanderbilt University
    Inventors: Jill M. Pulley, Robert R. Lavieri
  • Patent number: 11473013
    Abstract: A magnetic soil remediation agent for soil heavy metal pollution and a preparation method and application thereof are provided. The magnetic soil remediation agent is prepared by using remediation agent framework material and magnetic core material as raw materials, and heavy metal collector as modifier; said framework material is silicon dioxide activated by strong alkali; said magnetic core material comprises magnetic materials Fe3O4 and ?-Fe2O3; said modifier comprises ethylenediaminetetraacetic acid (EDTA), nitrilotriacetic acid trisodium salt (NTA), (S,S)-ethylenediamine-N,N-disuccinic acid trisodium salt (EDDS) and mercaptoethylamine. The remediation agent of the present invention can effectively passivate the heavy metals in the soil, reduce their available contents, and inhibit the absorption of heavy metals by plants.
    Type: Grant
    Filed: April 29, 2022
    Date of Patent: October 18, 2022
    Assignee: SOUTH CHINA NORMAL UNIVERSITY
    Inventors: Tao Chen, Bo Yan, Jian Huang
  • Patent number: 11471565
    Abstract: A modular engineered tissue construct includes a plurality of fused self-assembled, scaffold-free, high-density cell aggregates. At least one cell aggregate includes a plurality of cells and a plurality of biocompatible and biodegradable nanoparticles and/or microparticles that are incorporated within the cell aggregates. The nanoparticles and/or microparticles acting as a bulking agent within the cell aggregate to increase the cell aggregate size and/or thickness and improve the mechanical properties of the cell aggregate as well as to deliver bioactive agents.
    Type: Grant
    Filed: March 9, 2015
    Date of Patent: October 18, 2022
    Assignees: CASE WESTERN RESERVE UNIVERSITY, WORCESTER POLYTECHNIC INSTITUTE
    Inventors: Eben Alsberg, Anna D. Dikina, Marsha W. Rolle