Abstract: Methods and systems relate to determining sensory motor performance based on user non-postural movements within a generated dynamic virtual environment. The generated environment requires users to: (i) utilize primary sensor inputs (e.g., vision, vestibular sensation and somatosensation); (ii) assess the dynamic virtual environment; and (iii) integrate and translate those inputs into movement to control the dynamic virtual environment. The methods may include receiving non-postural user input with respect to a state of one or more attributes of a dynamic virtual environment provided on a user interface for one or more sessions, the one or more attributes including a control object and a target which moves with respect to the control object; determining performance information based on the user input and the state of the one or more attributes for the one or more sessions; and determining sensory motor performance information from the performance information.

Abstract: A compliant crank slider with adjustable constant-force output. Constant-force mechanisms (CFM) are used to maintain a constant output reaction force throughout a large range of compressive motion. The invention improves on existing CFM by introducing a second degree of freedom that adjusts the mechanism's output without changing its kinematic structure. This second degree of freedom is the rotation of a compliant beam about its longitudinal axis as it is constrained to the initial plane of bending. The resulting change in the beam's stiffness allows for adjustment to a specifiable range of constant-force outputs.

Abstract: This disclosure relates to systems and methods for measuring wave fields of a body of water. A system can include a radiation source and an antenna that can cooperate with the radiation source to transmit a radio frequency (RF) signal to a wave field having one or more waves. The antenna can receive backscattered signals from the wave field. The system can include a local oscillator and a processor. The local oscillator downconverts the backscattered signals into baseband signals and the processor can process the baseband signals to determine a relative velocity of each of the waves of the wave field. The processor can further be programmed to identify an observed portion of the backscattered signals as bad data and remove the bad data from further processing.

Abstract: An injectable carboxymethylcellulose (CMC) and methylcellulose (MC) hydrogel derived from the plant-based polysaccharide, cellulose, is provided which gels in situ and repairs the intervertebral disc in the spinal column or other cartilaginous tissues. One specific application is for replacement of the nucleus pulposus (NP), the central gelatinous region of the intervertebral disc, following injury or degeneration.

Abstract: Disclosed herein is a semiconducting nanoparticle comprising a one-dimensional semiconducting nanoparticle having a first end and a second end; where the second end is opposed to the first end; and two first endcaps, one of which contacts the first end and the other of which contacts the second end respectively of the one-dimensional semiconducting nanoparticle; where the first endcap that contacts the first end comprises a first semiconductor and where the first endcap extends from the first end of the one-dimensional semiconducting nanoparticle to form a first nanocrystal heterojunction; where the first endcap that contacts the second end comprises a second semiconductor; where the first endcap extends from the second end of the one-dimensional semiconducting nanoparticle to form a second nanocrystal heterojunction; and where the first semiconductor and the second semiconductor are chemically different from each other.

Abstract: The present invention relates to novel hydroxamic acids which are specific histone deacetylase (HDAC) inhibitors and/or TTK/Mps1 kinase inhibitors, including pharmaceutically acceptable salts thereof, which are useful for modulating HDAC and/or TTK/Mps1 kinase activity, pharmaceutical compositions comprising these compounds, and processes for their preparation.

Abstract: The present disclosure relates to composites of hollow carbon nanospheres (HCNS) and a metal, a metalloid, an alloy, a compound thereof, or any combination of the foregoing, and the use of such composites for making ion storage materials, such as negative electrode active material for lithium ion batteries.

Abstract: A program that supports emergency determination with an information terminal (1) equipped with a display (11) and a touch panel (12). The program makes the information terminal function as: an input reception unit (102) configured to receive input of age and sex on an injured or ill person through the touch panel (12); the input reception unit (102) configured to display a plurality of symptoms on the display (11) to allow a user to select any symptom from the plurality of symptoms through the touch panel (12), and an emergency determination unit (103) configured to determine the level of emergency degree corresponding to the age and the sex of the injured or ill person and the selected symptom and display the emergency degree on the display (11). This enables determination of the emergency degree of symptoms as well as notification of the determined emergency degree to the individual using an information terminal owned by the individual.

Abstract: The various embodiments disclosed here relate to systems, methods, and devices for monitoring bladder health. Certain implementations are directed to patients who require daily catheterization. The various embodiments have at least one tube coupled to a catheter, a pressure sensor, a pump, and a processor. Certain embodiments include a digital device with a software application capable of displaying the monitored readings.

Abstract: A transparent luminescent solar concentrator is provided. The transparent luminescent solar concentrator has luminophores embedded within a waveguide matrix that both selectively absorb and emit near-infrared light to an edge mounted or embedded solar photovoltaic array.

Abstract: Photo-protected microcapsules containing a photopolymer composition are dispersed in an epoxy coating to form an autonomic self-healing material. The capsule shell wall is formulated to protect the photopolymer composition from electromagnetic radiation exposure prior to rupture of the capsule shell, so that the photopolymer composition (e.g., a UV curable epoxy resin) remains active until triggered by damage to the capsule shell. Carbon black pigment is a suitable UV protector for the capsules. Upon sufficient damage to a region of the coating, the capsules will rupture and the photopolymer composition will fill and cure in and/or around the damaged region in the presence of electromagnetic radiation, achieving autonomic healing of the damaged coating.

Abstract: A superhydrophobic appliance is an elastomeric material with a surface having a multiplicity of re-entrant features. The elastomeric material can be a polydimethylsiloxane network. The superhydrophobic appliance can be formed by infusing a portion of a polydimethylsiloxane polymeric precursor partially into the pores of a porous membrane, curing to the polymeric network, and separating the membrane from the appliance to expose the superhydrophobic surface. The superhydrophobic surface can be subsequently modified to form a fluorinated surface that is oleophobic or superoleophobic in addition to being superhydrophobic.

Abstract: A base element for switching a magnetization state of a nanomagnet includes a heavy-metal strip having a surface. A ferromagnetic nanomagnet is disposed adjacent to the surface. The ferromagnetic nanomagnet has a first magnetization equilibrium state and a second magnetization equilibrium state. The first magnetization equilibrium state or the second magnetization equilibrium state is settable in an absence of an external magnetic field by a flow of electrical charge through the heavy-metal strip. A method for switching a magnetization state of a nanomagnet is also described.

Abstract: A controller for an artificial pancreas for automated insulin delivery to patients with type 1 diabetes mellitus (T1DM) that enforces safe insulin delivery throughout both day and night, wherein the controller employs zone model predictive control, whereby real-time optimization, based on a model of a human's insulin response, is utilized to regulate blood glucose levels to a safe zone, and time-dependent zones that smoothly modulate the controller correction based on the time of day, wherein the controller strategically strives to maintain an 80-140 mg/dL glucose zone during the day, a 110-220 mg/dL zone at night, and a smooth transition of 2 hour duration in between.

Abstract: Disclosed herein are an artificial cell membrane including a supported lipid bilayer (SLB) including a substrate and mobility-decreased metal particles bonded onto the substrate; an analysis device or kit including the artificial cell membrane and examining the interactions between molecules, in which one molecule is bonded to the surface of a mobility-decreased metal particle bonded to the artificial cell membrane and the other molecule is bonded to the surface of a mobility-increased metal particle bonded to a lipid at a low valency; a method of examining the interactions between molecules using the analysis device; a kit for quantitative or qualitative analysis of a target material including the artificial cell membrane by plasmonic scattering measurements; and a multiple analysis kit capable of detecting a plurality of target materials using a plurality of metal particles having different plasmonic scattering wavelengths and/or having mobility on a supported lipid bilayer.

Abstract: Adeno-associated virus rh.20 sequences, vectors containing same, and methods of use are provided.

Abstract: A road boundary detection system includes: an optical scanner configured to emit a light to an object to acquire measurement data reflected from the object; and a processor configured to extract a plurality of straight lines in order of a priority on each of the plurality of straight lines when a higher priority is given to a straight line including more of the contact points, based on the measurement data, configured to calculate a score of each straight line by assigning a score to the contact point included in the extracted straight lines and by assigning a score to a non-contact point included in other straight line having the same angle as the contact point, and configured to select a road boundary according to the priority of the calculated score of each straight lines.

Abstract: A method of removing at least one cationic dye from an aqueous solution. The method includes contacting the aqueous solution with an adsorbent comprising a water-insoluble membrane disposed on a substrate. The water-insoluble membrane comprises cross-linked humic acid, at least one alginate, and hydroxyethyl cellulose. The contacting forms a treated aqueous solution having a lower concentration of the at least one cationic dye relative to the aqueous solution.

Abstract: Antisense molecules capable of binding to a selected target site in the dystrophin gene to induce exon skipping are described.