Abstract: In this work, a hydrophilic, yet slippery solid surface was developed. Because the surfaces are hydrophilic, there is significant affinity between the surface and contacting water, which results in substantial spreading of the contacting liquids on the surface. Due to their strong affinity, a high solid-liquid adhesion having virtually no mobility of the water on the surface occurs. However, counter-intuitively, the disclosed surfaces are highly slippery such that liquids can slide on the surface while maintaining their hydrophilicity. Demonstrated herein are water droplets that can slide on the surface under its own weight, when the hydrophilic, yet slippery solid surface is slightly tilted (?=3°). This indicates that the disclosed hydrophilic surfaces are slippery to water.

Abstract: A method for receiving signaling information in a digital broadcast system according to an embodiment of the present invention comprises: a step of receiving a plurality of frames in which signaling information of a second layer is inserted in a signaling area of a first layer or a packet of a first layer; and a step of determining the signaling information of the second layer from the signaling area of the first layer or the packet of the first layer, and receiving service data using at least one of the determined signaling information of the second layer and pre-stored signaling information of a second layer.

Abstract: This document provides methods and materials for treating cancer. For example, methods and materials for treating cancer using combinations of antigens are provided. For example, VSV vectors designed to express a GNAQ antigen, a TYRP1 antigen, and an N-RAS antigen can be used to reduce the number of cancer cells (e.g., uveal melanoma cells) within a mammal (e.g., a human). In some cases, VSV vectors designed to express a BRAF antigen, a TOPO-11a antigen, and a YB-I antigen can be used to reduce the number of cancer cells (e.g., skin melanoma cells) within a mammal (e.g., a human). The composition can comprise less than 50 separate nucleic acid molecules.

Abstract: The present disclosure relates to chemical compounds, methods for their discovery, and their therapeutic and research use. In particular, the present disclosure provides compounds as therapeutic agents against bacterial infections (e.g., biofilms). The present disclosure also provides topical formulations for use in methods for treating bacterial infections.

Abstract: The present invention relates to a fuel-cell system. This system includes an anode electrode; a cathode electrode; a separator positioned between the anode electrode and the cathode electrode, wherein the separator is not an ion exchange membrane; an anode catalyst; and a cathode catalyst, wherein the cathode catalyst is a non-precious metal catalyst or metal-free catalyst. The present invention also relates to a method of generating energy from crude fuel. This method involves providing a fuel-cell system and contacting the fuel-cell system with a crude fuel under conditions effective to generate energy from the crude fuel.

Abstract: The invention relates generally to new prostate cancer markers, and particularly to a class of cancer marked by the presence of missense mutations in SPOP, an E3 ubiquitin ligase component. The invention provides methods and materials for detecting and diagnosing prostate cancer by detecting these mutations and may be useful in predicting disease progression and response to therapy.

Abstract: Bio-Inks and methods of using compositions comprising the bio-Inks are disclosed. 3-D tissue repair and regeneration through precise and specific formation of biodegradable tissue scaffolds in a tissue site using the bio-inks are also provided. Specific methylacrylated gelatin hydrogels (MAC) and methacrylated chitosan (MACh) preparations formulated with sucrose, a silicate-containing component (such as laponite), and/or a cross-linking agent (such as a photo-initiator or chemical initiator), as well as powdered preparations of these, are also disclosed. Kits containing these preparations are provided for point-of-care tissue repair in vivo. Superior, more complete (up to 99.85% tissue regeneration within 4 weeks applied in situ), and rapid in situ tissue repair and bone formation are also demonstrated.

Abstract: A variety of targeting moiety peptide epitope complexes (TPECs) are described in different embodiments. In each of the embodiments, however, a targeting moiety may be used to deliver the TPEC to an area of unwanted cells, allowing for a therapeutic effect to be delivered locally. The TPEC also contains a plurality of T-cell epitopes. The TPEC further comprises cleavage sites that release the T-cell epitopes from the targeting agent, and in some embodiments from each other, when they are in the microenvironment of the unwanted cells. Although the arrangement and number of T-cell epitopes varies in different embodiments described herein, once cleaved from the targeting agent (and any neighboring T-cell epitopes), the T-cell epitopes function by stimulating an immune response against the unwanted cells.

Abstract: Disclosed is a magnetic resonance imaging (MRI) system. The disclosed MRI system includes a system controller capable of separately acquiring MR image signals of different elements existing in an object. The system controller includes a first system controller capable of acquiring an MR signal of a first element, and a second system controller capable of acquiring an MR signal of a second element different from the first element. The first system controller and the second system controller are physically separated. The first system controller and the second system controller control a first radio frequency (RF) coil element and a second RF coil element of an RF coil, respectively.

Abstract: An energy system includes a microgrid including a network of at least one distributed energy resource and a plurality of loads, the at least one distributed energy resource being configured to supply power to the plurality of loads. The microgrid is configurable to connect to one of a plurality of feeder circuits of a main power grid at one of a plurality of coupling interface locations, respectively. The microgrid is also configurable to expand or shrink its power supply area according to the available power generation capabilities.

Abstract: A sound reproduction system and filter set comprising an array of loudspeakers, comprises a plurality of delay-gain filter elements, and further wherein the filter set comprises a plurality of loudspeaker-specific filter elements (12) which are each associated with different respective speakers of the loudspeaker array, and further comprising a plurality of loudspeaker-independent filter elements (10) which are each common to a plurality of the loudspeakers of the array.

Abstract: A monolithic integration of phase change material (PCM) switches with a MEMS resonator is provided to implement switching and reconfiguration functionalities. MEMS resonator includes a piezoelectric material to control terminal connections to the electrodes. The PCM is operable between an ON state and an OFF state by application of heat, which causes the phase change material to change from an amorphous state to a crystalline state or from a crystalline state to an amorphous state, the amorphous state and the crystalline state each associated with one of the ON state and the OFF state. A method of fabricating the MEMS resonator with phase change material is provided. A reconfigurable filter system using the MEMS resonators is also provided.

Abstract: Embodiments include operations, apparatus, methods and other embodiments that access a baseline CT image of a region of tissue (ROT) demonstrating non-small cell lung cancer (NSCLC), segment a tumoral region represented in the baseline CT image; define a peritumoral region by dilating the tumoral boundary; extract a set of tumoral radiomic features from the tumoral region, a set of peritumoral radiomic features from the peritumoral region, and a set of clinico-pathologic features from the baseline CT image; provide the set of tumoral radiomic features, peritumoral radiomic features, and clinico-pathologic features to a machine learning classifier; receive, from the machine learning classifier, a time-to-recurrence post trimodality therapy (TMT) prediction, based on the set of tumoral radiomic features, peritumoral radiomic features, and clinico-pathologic features; generate a classification of the ROT as an MPR responder or MPR non-responder based, at least in part, on the time-to-recurrence post-TMT predicti

Abstract: Provided is an apparatus for loading a follicular unit to a needle for hair implant including a first slitless needle in which the other end of a hollow body has a wedge shape, one end of the hollow body has a tubular shape to facilitate force transmission, and an end surface of the one end is blunt, so as to be used in a transplantation region in hair transplant procedure, and a first instrument configured to push the follicular unit to an interior of the first needle to load the follicular unit to the interior of the first needle.

Abstract: A system and method for detection, reduction of combustion resonance and engine control is provided. The system senses ion current within one or each cylinder of a multi-cylinder engine and determines combustion resonance from the ion current signal. In addition, the system may determine an engine control strategy to reduce combustion resonance based on the feedback from the ion current signal.

Abstract: To better control part quality of 3D printed parts, the temperature of an extruder filament using a secondary heat source is provided. A heat source, such as an infrared heat source, can be used to heat the filament of a 3D printer to the optimum temperature that will enhance welding of the filament to a substrate that it is being printed on or to. Such an optimum temperature can be based upon, in part, the temperature of the substrate. A controller or other intelligent control can be used to receive temperature readings of the substrate and/or filament and then can adjust the temperature of the heating source to optimize the temperature of the filament to better combine the filament to the substrate.

Abstract: An integrated logic device includes a channel having an interconnect section and a pair of spin-orbit segments connected to the interconnect section at either end of the interconnect section. A P structure includes a P magnet disposed on a surface of a spin-orbit segment. A tunneling barrier is disposed between the P magnet and a Rp magnetic reference layer. A Q structure includes a Q magnet disposed on a surface of the other spin-orbit segment. A tunneling barrier is disposed between the Q magnet and a Rq magnetic reference layer. A method of integrated logic spin-orbit perpendicular-anisotropy (SOPE) gate device operation is also described.

Abstract: A magnetic device comprising having a first magnetic layer having a first magnetization direction, a second magnetic layer having a second magnetization direction, a first coupling layer interposed between the first and second magnetic layers, a third magnetic layer having a third magnetization direction, a first magnetoresistive layer interposed between the third magnetic layer and the second magnetic layer, and a circuit connected to one or more of the layers of the magnetic device by at least a pair of leads. The circuit is configured to determine a change in resistance between the pair of leads. The change in resistance is based at least in part on a change in an angular relationship between the third magnetization direction and the second magnetization direction caused by an external magnetic field or a current passing through at least a portion of the device.

Abstract: A lens-based integrated two-dimensional beam steering device comprising a substrate, an input waveguide, a connecting waveguide, a 1×N optical switch, an electrical interface for the switch, N output waveguides of the switch, N transmitting units, a lens and a controller. The device of the present invention realizes two-dimensional beam steering and has the characteristics of large power capacity, low control complexity, and low electric power consumption.

Abstract: The present invention generally relates to a method of treating or preventing an endoplasmic reticulum stress disorder in subjects, such as a method of treating or preventing Wolfram syndrome.