Abstract: Methods and devices for increasing endothelialization on a surface of a medical device are provided. The methods include delivering the medical device to an intravascular site and the medical device has an ?-gal epitope attached to the surface of the medical device.
Type:
Application
Filed:
June 12, 2019
Publication date:
August 26, 2021
Applicant:
Rush University Medical Center
Inventors:
Jeffrey Scott SOBLE, Uri GALILI, Gary SCHAER
Abstract: Novel chimeric proteins may be used to inhibit transcriptional activities that are mediated by transcription factor interactions with P-TEFb. The chimeras contain elements that recruit the target transcription factor, maintain CDK9 in an inactive state, and competitively inhibit P-TEFb binding to the transcription factor. The chimeras may be configured for inhibition of HIV Tat mediated transcription and thus provide a novel means of preventing reactivation of integrated HIV, providing a new tool for emerging “block and lock” HIV cure strategies.
Type:
Application
Filed:
April 1, 2021
Publication date:
August 26, 2021
Applicant:
The Regents of the University of California
Inventors:
Koh Fujinaga, Boris Peterlin, Marie Leoz
Abstract: A manufacturing system for an inkjet printing flexible display device includes a substrate input module, a substrate transferring module, a printing module, a post-printing processing module, a solid content detection module, a film packaging printing module, a film formation detection module, a substrate output module. At the same time, the functional modules are highly integrated and optimized in structure and layout. The manufacturing system for the inkjet printing flexible display device is suitable for industrial production and are adopted to monitor the manufacturing process by using a plurality of detection modules.
Type:
Application
Filed:
May 15, 2020
Publication date:
August 26, 2021
Applicant:
HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
Abstract: An object of the present invention is to provide a novel composition for use in suppressing fat accumulation, a novel composition for use in suppressing body weight gain, and a composition for use in promoting the production of a ketone body. According to the present invention, there is provided a composition for use in suppressing fat accumulation, suppressing body weight gain and/or promoting the production of a ketone body, comprising, as an active ingredient, a medium chain fatty acid glyceride comprising a saturated fatty acid having 8 carbon atoms as a constituent fatty acid. The ratio of the amount of the saturated fatty acid having 8 carbon atoms to the total amount of medium chain fatty acids of the medium chain fatty acid glyceride can be set to 0.6 or more. The medium chain fatty acid glyceride may further comprise, as a constituent fatty acid, a saturated fatty acid having 10 carbon atoms and/or a saturated fatty acid having 12 carbon atoms.
Type:
Application
Filed:
July 2, 2019
Publication date:
August 26, 2021
Applicants:
National University Corporation Tokyo University of Agriculture and Technology, THE FOOD SCIENCE INSTITUTE FOUNDATION, MEIJI CO., LTD.
Abstract: A LiDAR point cloud reflection intensity complementation method includes: acquiring a grayscale image and an original point cloud of a same road surface using a calibrated vehicle-mounted webcam and LiDAR; extracting edge information of the grayscale image using a preset edge extraction strategy, to obtain an edge image of the grayscale image; preprocessing the original point cloud to obtain an original point cloud reflection intensity projection image and an interpolated complementary point cloud reflection intensity projection image; and inputting the grayscale image, the edge image of the grayscale image, the original point cloud reflection intensity projection image and the interpolated complementary point cloud reflection intensity projection image into a pre-trained point cloud reflection intensity complementation model, and outputting a complementary point cloud reflection intensity projection image. A LiDAR point cloud reflection intensity complementation system is further provided.
Abstract: A freeform surface off-axial three-mirror imaging system comprising a primary mirror, a secondary mirror, a tertiary mirror, and a detector. The secondary mirror comprises a first freeform surface and a second freeform surface. Each reflective surface of the primary mirror, the first freeform surface, the second freeform surface and the tertiary mirror is an xy polynomial freeform surface. The freeform surface off-axial three-mirror imaging system comprises a first effective focal length and a second effective focal length different from the first effective focal length.
Type:
Grant
Filed:
July 3, 2019
Date of Patent:
August 24, 2021
Assignees:
Tsinghua University, HON HAI PRECISION INDUSTRY CO., LTD.
Inventors:
Jun Zhu, Rui-rui Tang, Guo-Fan Jin, Shou-Shan Fan
Abstract: A nanocarrier including a silica body having a surface and defining a plurality of pores that are suitable to receive molecules therein is described. The nanocarrier also includes a lipid bilayer coating the surface, and a cargo-trapping agent within the phospholipid bilayer. The phospholipid bilayer stably seals the plurality of pores. The cargo-trapping reagent can be selected to interact with a desired cargo, such as a drug.
Type:
Grant
Filed:
August 5, 2020
Date of Patent:
August 24, 2021
Assignee:
The Regents of the University of California
Inventors:
Andre E. Nel, Huan Meng, Xiangsheng Liu
Abstract: Methods, computing devices, and computer-readable medium are described herein related to producing detection signals configured to induce an excited state of an object. A computing device may receive reflection signals, where the reflection signals correspond to at least one detection signals reflected from the object. Based on the received reflection signals, a presence of the object in the excited state may be determined. Further, an output device may provide an indication of the presence of the object in the excited state.
Type:
Grant
Filed:
November 1, 2018
Date of Patent:
August 24, 2021
Assignee:
University of Washington through its Center for
Commercialization
Inventors:
Michael R. Bailey, Wei Lu, Oleg A. Sapozhnikov, Bryan Cunitz
Abstract: The disclosure discloses a synthetic method for benzimidazo[1,2-c]quinazolin-6-ones and belongs to the field of organic synthesis. In the disclosure, an ?-ketoamide compound shown as Formula I and an o-phenylenediamine compound shown as Formula II are used as substrates and undergo a reaction under the action of a catalyst and a base to obtain benzimidazo[1,2-c]quinazolin-6-ones shown as Formula III. In the disclosure, benzimidazo[1,2-c]quinazolin-6-ones are prepared based on a novel and efficient action mechanism, and the disclosure has the advantages that the raw materials are cheap, the catalyst is cheap and easy to obtain, the reaction is efficient and environmentally friendly, the substrate range is wide, the yield is high, and the operation is simple.
Abstract: Provided is a method, device, and computer-readable medium for controlling a robot graphic user interface (“RGUI”) on a mobile device. The method can include determining a distance, a position, or both of the mobile device with respect to a first robot; and causing, by a processor, a first RGUI to be displayed on a display of the mobile device based on the determining.
Abstract: A device that includes a scaffold composition and a bioactive composition with the bioactive composition being incorporated into or coated onto the scaffold composition such that the scaffold composition and/or a bioactive composition controls egress of a resident cell or progeny thereof. The devices mediate active recruitment, modification, and release of host cells from the material.
Type:
Grant
Filed:
October 25, 2018
Date of Patent:
August 24, 2021
Assignees:
President and Fellows of Harvard College, Regents of the University of Michigan
Inventors:
David J. Mooney, Omar Abdel-Rahman Ali, Eduardo Alexandre Barros E Silva, Hyun Joon Kong, Elliot Earl Hill, Jr., Tanyarut Boontheekul
Abstract: A wireless sensor network node selection that efficiently manages active nodes using a Tabu heuristic coupled with minimum spanning tree routing protocol (TNS-MST) is presented. Nodal energy consumption is balanced to ensure all nodes are operating at the same energy level. To balance the energy consumption, nodes with high energy depletion are removed from routing by placing on them a Tabu list, which prevents the most used nodes, such as nodes close to a base station, from draining before their neighbors. The nodes in the Tabu lists are dynamically active according to the energy level of neighboring nodes. The Tabu list combined with Minimum Spanning Tree routing protocol, TNS-MST, greatly increases network lifetime by optimally balancing the energy of the sensor nodes.
Abstract: A driving service active sensing system and method in an Internet of Vehicles environment in the field of road traffic safety. A sensor device and an intelligent vehicle-mounted terminal arranged on a vehicle and connected to each other. The intelligent vehicle-mounted terminal communicates with roadside equipment in 4G and DSRC modes, and communicates with a driving service information processing center in 4G mode. The roadside equipment communicates with the driving service information processing center in 4G mode. The roadside equipment is provided on both sides of a road. The sensor device outputs obtained vehicle traveling information to the intelligent vehicle-mounted terminal, which processes and integrates the received vehicle traveling information and then transfers integrated information to the roadside equipment and the driving service information processing center.
Type:
Grant
Filed:
September 21, 2016
Date of Patent:
August 24, 2021
Assignee:
Jiangsu University
Inventors:
Jun Liang, Zhenchao Zhao, Long Chen, Haobin Jiang, Xiaobo Chen, Shidian Ma, Weiqi Zhou, Yingfeng Cai, Tongyang Zhao
Abstract: Methods of making magnesium-based compositions are disclosed. The methods include the addition of a metallic magnesium powder to a magnesium salt, a metal halide and a solvent. The methods provide compositions with advantageous properties that make them useful as electrolytes for battery applications.
Abstract: An upconversion system, including: a glow discharge device (GDD) configured to detect signal source radiation, wherein the signal source radiation is at least one of millimeter wave (MMW) radiation and Terahertz (THz) radiation; and a photodetector configured to measure intensity changes in visible light emitted by said GDD as a result of absorption of the signal source radiation. The upconversion system optionally includes a processor operatively coupled to the photodetector. The processor is configured to analyze imagery captured by the photodetector, and to compute at least one parameter of the signal source radiation based on the imagery.
Type:
Grant
Filed:
July 17, 2017
Date of Patent:
August 24, 2021
Assignees:
B. G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY, ARIEL SCIENTIFIC INNOVATIONS LTD.
Inventors:
Natan Kopeika, Amir Abramovich, Yitzhak Yitzhaky, Avihai Aharon, Daniel Rozban
Abstract: Ultrasound methods, devices, and systems are described which support a useful compromise in terms of spatial resolution and temporal resolution for capturing motion in tissue structures. Tissue engineering articles, methods, systems, and devices which employ ultrasound to deliver biological agents to selected regions of a tissue scaffold, deliver mechanical stimulation to cells growing in a tissue scaffold, and enhance the perfusion of fluids through tissue scaffolds.
Type:
Grant
Filed:
April 8, 2016
Date of Patent:
August 24, 2021
Assignee:
The Trustees of Columbia University in the City of New York
Inventors:
Elisa E. Konofagou, Jean Provost, Jianwen Luo, Stanley J. Okrasinski, Stéphane Thiébaut, Vu Thanh-Hieu Nguyen
Abstract: A photonic device (100) comprising: an optical waveguide (101), and a modulating element (102) that is evanescently coupled to the waveguide (101); wherein the modulating element (102) modifies a transmission, reflection or absorption characteristic of the waveguide (101) dependant on its state, and the state of the modulating element (102) is switchable by an optical switching signal (125) carried by the waveguide (101), or by an electrical signal that heats the modulating element (102).
Type:
Grant
Filed:
August 23, 2019
Date of Patent:
August 24, 2021
Assignee:
OXFORD UNIVERSITY INNOVATION LTD.
Inventors:
Carlos Rios, Harish Bhaskaran, Wolfram Pernice, Matthias Stegmaier
Abstract: Disclosed are daidzein analogs having the formula (I). Also disclosed are compositions, include a disclosed daidzein analogs, methods of preventing or treating bone disease or bone injury and/or stimulating bone growth, in a subject that include administering to the subject an effective amount of disclosed daidzein analog. Disclosed are isolated mesenchymal stem cell that has been altered by treatment a disclosed daidzein analog, daidzein, glycinol, glyceollin I, or glyceollin II, to increase the osteogenic potential of the mesenchymal stem cells.
Type:
Grant
Filed:
April 4, 2014
Date of Patent:
August 24, 2021
Assignees:
THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, XAVIER UNIVERSITY OF LOUISIANA, THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE
Inventors:
Amy Strong, Stephen Boue, Matthew Burow, Bruce Bunnell, Quan Jiang, Shilong Zheng, Guangdi Wang