Abstract: A passive cavitation mapping method is provided that includes capturing a channel signal from at least one ultrasound transducer in an array of ultrasound transducers, isolating a cavitation signal in the channel signal, time-gating the channel signal about the cavitation signal, computing a time-delay between neighboring the cavitation signals in adjacent the channel signals, computing a modified parabolic fit to the square of the arrival times, where the modified parabolic fit includes a coordinate transformation using an x location of a leading edge of wavefronts of the cavitation signal and a maximum arrival time of the cavitation signal, extracting a location of a cavitation signal source at point (x, z) in the coordinate transformation, computing a cavitation magnitude for each non-eliminated cavitation signal, creating a passive cavitation map by convolving the cavitation magnitude and the source location with an uncertainty function, and using the cavitation map for therapeutic ultrasound applications

Abstract: A system and method for cardiac activation imaging includes non-invasively or minimally invasively acquiring data about an electrical activation of a heart of a subject using at least one sensor. An activation image of the heart of the subject is reconstructed using a weighted sparse constrained reconstruction.

Abstract: Methods and compositions for the treatment, amelioration, or prevention of cancer and/or cancer metastasis by delivery of a hemodynamics altering agent such as a drag reducing polymer (DRP).

Abstract: A rubber belt retracting and deploying device for a belt conveyor includes a base, mounting frames, an upper caterpillar disk, a middle caterpillar disk and a lower caterpillar disk, wherein the lower caterpillar disk is fixedly connected between the symmetric mounting frames, and the middle caterpillar disk is movably connected between the symmetric mounting frames, and may longitudinally slide along the symmetric mounting, frames, such that the lower caterpillar disk and the middle caterpillar disk form a first clamping device; the upper caterpillar disk is movably connected between the symmetric mounting frames, and may longitudinally slide along the symmetric mounting frames, such that the upper caterpillar disk and the middle caterpillar disk form a second clamping device; each of the upper caterpillar disk, the middle caterpillar disk and the lower caterpillar disk is provided with a driving part.

Abstract: A cell culture device comprises a first inner cylinder formed in a tubular shape, a cell culture membrane placed to cover over an entire one end of the first inner cylinder and configured to be folded down toward an outer surface of the first inner cylinder along an outer circumference at the one end of the first inner cylinder, and an outer cylinder formed in a tubular shape, configured to place the first inner cylinder inside thereof such that a height direction of the outer cylinder is identical with a height direction of the first inner cylinder, and provided with a first slit in an area overlapping with at least the one end of the first inner cylinder to be extended in the height direction, wherein the cell culture membrane is held between an inner wall surface of the outer cylinder and the outer surface of the first inner cylinder.

Abstract: The invention is a capacitive, aka electrostatic, deionization apparatus and method that solves the problem of short lifetime of conventional capacitive deionization (CDI) and of membrane capacitive deionization (MCDI) devices and methods by shifting the Potential of Zero Charge of electrode surfaces through surface modifications. Such electrode surface modifications provide very long lifetime capacitive deionization devices and methods.

Abstract: A substrate for the detection of a biological target by Scanning Electrochemical Microscopy (SECM) is provided. The substrate includes: a conductive surface; a probe area provided on the conductive surface, the probe area comprising receptors responsive to the biological target; and a background area provided on the conductive surface, the background area being disposed around the probe area and comprising electroactive compounds providing imaging contrast between the background area and the probe area.

Abstract: In one aspect, the invention relates to methods and compositions for determining migration of a virus particle to the nucleus of a cell. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: The present disclosure describes a system and method of depositing ceramic or ceramic composite coatings on the inside surface area of a tubular shape. The system and method described herein can provide an interior coating for tubes and pipes to provide wear resistance, abrasion resistance, and anti-scaling effects.

Abstract: A laser tip, a laser treatment tool, a laser treatment device and a laser treatment system are provided for performing laser treatment surgery and minimizing any bleeding. A laser tip is attachable to a laser radiation opening located at the tip end of a laser transmission tube. The laser tip includes an attaching portion detachable from the laser radiation opening and a contact portion contactable with biological tissue. The contact portion is at the front of the attaching portion in the direction in which the laser light exits the laser radiation opening. An open space is located between the contact portion and the attaching portion, and a coupler couples a part of the contact portion and a part of the attaching portion. The contact portion has a reflective surface at a rear end thereof which reflects the laser light toward the coupler.

Abstract: The present invention provides pharmaceutical compounds and methods for preventing, ameliorating, or treating a mitochondrial disease by administering such compounds to a subject in need thereof. In some cases, the subject suffers from a mitochondrial disease or is predisposed to having a mitochondrial disease. The mitochondrial disease includes those associated with impairments to mitochondrial oxidative phosphorylation that can lead to vision loss or blindness.

Abstract: Lidar is an acronym for Light Detection And Ranging. The technology may be used to measure distance by illuminating a target with a laser beam and performing analysis on the reflected laser beam light. In the atmospheric sciences, Lidar may be used to study the optical depth of clouds, the impact of aerosols on clouds, and the interactions between aerosols and clouds on the climate. The present application proposes a lidar-based technology using a diode laser (101) beam sent through a tapered semiconductor optical amplifier (106) and an axicon pair expander (108) wherein the laser light may be transmitted through a telescope (110) at an object to be studied. Upon striking the object to be studied, the laser (101) is reflected and recovered by the telescope (110). The reflected laser is then sent through a heated rubidium vapor cell (115) and a total detection channel (116) for analysis.

Abstract: An intraoperative nerve evaluation device includes a flexible substrate, and a plurality of detection units disposed on the substrate and spaced apart from one another. Each of the detection units includes an electrode and a conductive wire electrically connected to the electrode. When the electrodes are attached to a nerve, a selected one of the electrodes is configured to receive an input signal via the corresponding conductive wire and to transmit the input signal to the nerve, and each of the electrodes other than the selected one is configured to receive from the nerve a response signal associated with the input signal and to transmit the response signal via the corresponding conductive wire.

Abstract: Fusion peptides and methods of inhibiting GrB-EHITSN or a fragment thereof are provided. The fusion peptides include an NPF peptide and a cell-permeable peptide operably connected thereto. Fusion peptides and methods of inhibiting activity of GrB-EHITSN or fragment thereof are provided. An aspect includes a fusion peptide comprising an isolated NPF peptide comprising an amino acid sequence having at least 90% identity to SEQ ID NO: 2 and a cell-permeable peptide operably connected to the isolated NPF peptide, wherein the fusion peptide inhibits activity of GrB-EHITSN or a fragment thereof.

Abstract: A reinforced compound concrete beam-column joint containing demolished concrete lumps and a construction method are disclosed. The steel strip stirrups configured to constrain column longitudinal reinforcements of the reinforced compound concrete column containing demolished concrete lumps and the steel connection sheets with grooves are arranged in joint at positions of the upper and lower beam longitudinal reinforcements of the reinforced compound concrete beam containing demolished concrete lumps. The steel strip stirrups abut against the column longitudinal reinforcements. The steel connection sheets are welded to the steel strip stirrups. One end of the short steel bars with threads at one end is welded into the grooves of the steel connection sheets, and the other end is connected to the beam longitudinal reinforcement via a steel sleeve. The joint prevents the beam longitudinal reinforcements from passing through the joint and thus causing reinforcements congestion.

Abstract: The method of synthesis of bio graphene may include mixing carrageenan with a bio waste solution, adding graphene oxide to produce a mixture, sonicating the mixture, and evaporative-casting the mixture to produce bio graphene film. In an embodiment, the carrageenan may be ?-carrageenan. In an embodiment, the bio waste solution may include fish scales.

Abstract: A microfabricated gas flow structure includes an array of vertical gas flow channels in a side-by-side parallel flow arrangement. Adjacent gas flow channels are separated by a thin wall having a thickness which can be an order of magnitude or more less than the channel width, offering exceptionally high area efficiency for the array. Channel walls can be formed from a dielectric material to provide the walls with sufficient integrity at nanoscale thicknesses and to provide thermal insulative properties in the lateral direction, thereby controlling power losses when the gas flow structure is employed as a Knudsen pump. The gas flow structure can be microfabricated as a monolithic structure from an SOI wafer, with the gas flow channels formed in the device layer and the heat sink formed from the handle layer.

Abstract: The invention relates, in part, to methods and compositions that are useful to modulate metabolic function of cells in vivo or in vitro. In some aspects the invention includes methods and/or compositions that increase metabolism in cells, tissues, organs, and/or subjects. In certain aspects the invention includes methods and/or compositions useful to decrease metabolism in cells, tissues, organs, and/or in subjects.

Abstract: Provided herein are methods, compositions, and devices for occluding cavities or passageways in a patient, in particular cavities or passageways in the cardiovascular system of a patient, such as the LAA of a patient's heart. The methods, compositions, and devices can be used to percutaneously occlude the LAA, decreasing the risk of thromboembolic events associated with AF.

Abstract: A wireless communication system may include an SGW operably coupled to a PGW to setup a session responsive to a request from a terminal to establish the session between the terminal and the PGW. The system further includes an MME configured to authenticate the terminal and provide bearer management in response to the request. The MME is configured to provide bearer information to the SGW. The system also includes base stations operably coupled to the SGW via a data plane connection and operably coupled to the MME via a control plane connection. The base stations are configured to handover connection to the terminal between the base stations in response to movement of the terminal between coverage areas of the base stations.