Abstract: Systems and methods are provided for configuring a human-machine interface according to a user's relative preference, or weighting, of a set of utility factors, such that a user can customize a human-machine interface in the absence of the direct selection of interface parameters. In some example embodiments, a total utility function (associated with overall utility of a human-machine interface) is calculated based on the sum of a set of weighted utility functions, with each utility function being weighted according to a respective user-tunable weight, and with each user-tunable weight prescribing a relative importance of a respective utility factor to the total utility function. A set of parameters of the human-machine interface that optimize the overall utility function for a selected set of user-tunable weights is determined and employed to configure the human-machine interface.

Abstract: A method for treating an ocular disorder in a subject comprising administering a therapeutic agent-loaded carrier to an ocular site of the subject in need thereof, wherein the therapeutic agent loaded-carrier provides controlled delivery of the therapeutic agent under conditions suitable for recruiting regulatory T cells to an ocular region of interest or inducing regulatory T cells in an ocular region of interest.

Abstract: A preparation method of flexible transparent radiation shielding film based on bismuth compounds and its application are provided, in which bismuth compound nanoparticles, polyvinyl alcohol and trace glycerol are mixed to produce a flexible transparent radiation shielding film. The invention disperses the nanoparticles in water to form a stable dispersion, which ensures the homogeneity of the sol obtained by mixing the nanoparticles with polyvinyl alcohol. This invention avoids the decrease in transparency of the composite film as induced by agglomeration of the nanoparticles, achieving a light transmission of over 70% in the visible wavelength band (400-800 nm). With the aid of trace-mount glycerol, the film features long-term stability and flexibility. Importantly, the lead-free film shows a high shielding ability from the medical X-ray band (10-100 keV), which is comparable to Cu foil of identical thickness.

Abstract: An additive repair device for internal threads is provided. The device includes a moving assembly, a rotating assembly, a speed regulation assembly, a gear assembly, an additive assembly, and a connecting assembly. The moving assembly includes a drive part and a linear movement mechanism. The additive assembly is connected to the linear movement mechanism through the connecting assembly. One end, which is far away from the drive part, of the linear movement mechanism is connected to an input end of the speed regulation assembly through the gear assembly. The rotating assembly includes a clutch mechanism and a clamping mechanism. The clutch mechanism includes a clutch outer gear and a clutch inner gear. The clutch outer gear is arranged at an output end of the speed regulation assembly. The clamping mechanism is fixed to one end, which is far away from the speed regulation assembly, of the clutch inner gear.

Abstract: Provided is a functional, low-profile intercranial device (LID). The LID includes a base portion; at least one cavity associated with the base portion and configured to accept at least one functional component; and at least one conduit having a first end in communication with the at least one cavity. The at least one functional component includes a medicinal, electronic, or optic therapeutic. The at least one conduit is configured to accept the medicinal therapeutic and a second end configured to dispense the therapeutic.

Abstract: A double-sided ultrasonic rolling cooperative strengthening system and a control method thereof are provided. The system includes a first mechanical arm subsystem, a second mechanical arm subsystem, a first ultrasonic rolling strengthening subsystem, a second ultrasonic rolling strengthening subsystem and a servo turntable (13); the servo turntable (13) is configured to fix a blade to be processed; the first ultrasonic rolling strengthening subsystem is provided at an end of the first mechanical arm subsystem; and the second ultrasonic rolling strengthening subsystem is provided at an end of the second mechanical arm subsystem.

Abstract: A field magnet holder provided at a field portion of an electric motor is formed of a non-magnetic material. An inner wall and outer wall of the field magnet holder are respectively formed in annular shapes. Plural spacers are arranged between the inner wall and outer wall at a predetermined spacing in the circumferential direction. Sockets into which permanent magnets are inserted are formed between the spacers of the field magnet holder, plurally in the circumferential direction. Therefore, the permanent magnets may be easily assembled by being respectively inserted into the sockets. The plural permanent magnets are arrayed with magnetization directions thereof successively changed in steps of an angle that is a full cycle of electrical angles divided by a division number n, which division number n is any one integer that is at least three. Thus, ease of assembly of the permanent magnets is improved.

Abstract: A read and write circuit of a three-dimensional phase-change memory including an operation control circuit and a read and write operation circuit connected to each other. The operation control circuit is configured to load a correct operation pulse onto the read and write operation circuit. A read and write unit in the read and write operation circuit is connected to a memory cell and is configured to load the correct operation pulse onto the memory cell corresponding to the three-dimensional phase-change memory and to mirror the correct operation pulse to a mirror current. A bandgap reference source and a hysteresis comparator are connected to a mirror circuit branch. A feedback chopper circuit loop is connected across the memory cell and the mirror circuit branch and is configured to monitor a current flowing through the memory cell in real time.

Abstract: A two-dimensional photonic-crystal surface-emitting laser includes an active layer; and a photonic-crystal layer including a two-dimensional photonic-crystal light-amplification portion that is a first two-dimensional photonic-crystal region provided in a plate-shaped base body disposed on one side of the active layer, and includes an amplification-portion photonic band gap which is a photonic band gap formed between two photonic bands having a band edge at a predetermined point in a reciprocal lattice space, and a two-dimensional photonic-crystal light-reflection portion that is a second two-dimensional photonic-crystal region provided around the two-dimensional photonic-crystal light-amplification portion, and includes a reflection-portion photonic band gap which is a photonic band gap formed between two photonic bands having a band edge at the predetermined point of the reciprocal lattice space, wherein energy ranges of the amplification-portion photonic band gap and the reflection-portion photonic band ga

Abstract: The present invention relates to a monoclonal antibody specifically recognizing a spike protein of MERS coronavirus (MERS-CoV) or a part of the protein, or a functional fragment thereof, wherein the monoclonal antibody, or functional fragment of the monoclonal antibody characterized in that it comprises polypeptide sequence selected from the group consisting of the following polypeptide sequences: a heavy chain comprising a complementarity determining region 1 (CDR 1) amino acid sequence consisting of the sequence of SEQ ID NO: 1, a CDR2 consisting of the sequence of SEQ ID NO: 2 and a CDR 3 consisting of the sequence of SEQ ID NO: 3; and a light chain comprising CDR1 amino acid sequence consisting of the sequence of SEQ ID NO: 4, a CDR2 consisting of the sequence of SEQ ID NO: 5 and a CDR 3 consisting of the sequence of SEQ ID NO: 6. and uses thereof.

Abstract: A method of inhibiting cyclooxygenase (COX) enzyme activity in a patient including administering to a patient in need thereof a therapeutically effective amount of tolterodine.

Abstract: A method of forming an image of a region of interest using a pulse-echo imaging device is described. The method includes the steps of generating a pulse using the pulse-echo imaging device, causing the pulse to be incident on the region of interest to generate a reflected echo, receiving the reflected echo in the pulse-echo imaging device, comparing a measure of frequency content of the reflected echo to the transmitted pulse, and frequency shifted replicas of the transmitted pulse, wherein each is associated with a unique label, selecting a label based on the comparison, and generating an image incorporating the selected label.

Abstract: A method for treating or preventing nociceptive pain by administering an ethanol extract of Brazilian green propolis and compositions comprising this extract.

Abstract: A method of making a smart optical material (SOM) including mixing polypropylene in a solvent to form a first solution. The method further includes mixing a zinc salt in 2-hydroxyethyl methacrylate and heating it to form a second solution. The method further includes mixing rhodamine B and a peroxide into the second solution to form a third solution. The method further includes mixing the third solution into the first solution to form a reaction solution, wherein the peroxide initiates polymerization of the 2-hydroxyethyl methacrylate to form poly (2-hydroxyethyl methacrylate). The method further includes separating the SOM from the reaction solution. The SOM has at least two bandgaps, a first bandgap is from 1.4-1.5 eV, and a second bandgap is from 1.8-1.9 eV.

Abstract: A guiding sheath system includes a first sheath having a proximal end and a distal end, an extension member connected to the distal end of the first sheath, the extension member terminating in a distal end, a second sheath extending through the first sheath, the second sheath having a proximal end and a distal end, and a cap connected to the distal end of the extension member and the distal end of the second sheath. Upon advancing the second sheath through the first sheath, the cap restrains the distal end of the second sheath and the cap deflects relative to the first sheath thereby causing a portion of the second sheath protruding from the first sheath to bend into a curve with the distal end of the second sheath at a vector different from a vector of the first sheath.

Abstract: The disclosure provides compounds of formula (II) having the structure: Compounds of formula (II) are fractalkine receptor agonists and useful in treating, preventing or minimizing metastasis in a subject diagnosed with cancer. The compounds of the disclosure are further useful in treating central nervous system diseases (such as, but not limited to, HIV Associated Neurocognitive Disorders (HAND), and/or Alzheimer's disease), pain, inflammation (such as, but not limited to, arthritis), cardiovascular disease (such as, but not limited to, undesired vascular smooth muscle proliferation, atherosclerosis, coronary vascular endothelial dysfunction, and/or coronary artery disease), and/or multiple sclerosis.

Abstract: The disclosure belongs to the technical field of radiomics, and particularly relates to an extraction method for radiomics feature information of knee joint effusion. each layer of an image is segmented into a plurality of regions, the interference of image noises in each region is removed, then whether each region after interference removal is an effusion region or not is judged, finally, the radiomics features of each effusion region are calculated, interpolation processing is respectively implemented on the obtained image position and the area of the effusion regions, an effusion area simulation change curve is drawn, curve integration is implemented to obtain volume information, and all the extracted information is stored in a cell array of a MATLAB. thus the effusion information in the MRI image of the knee joint is automatically extracted, and meanwhile, the method is fast in speed, high in accuracy, good in repeatability.

Abstract: A system for non-destructive testing of a bond condition of concrete beams reinforced by steel rods is described. The system includes a transducing transmitter, a transducing receiver, and an ultrasonic pulse generator configured to generate drive signals for the transducing transmitter and receive a plurality vibrational waves at the transducing receiver. The system further includes a computing device including a measurement circuit configured to record a transit time for each vibrational wave and divide a distance between the transducing transmitter and the transducing receiver by the transit time to determine a pulse velocity of each vibrational wave, a comparison circuit configured to identify a highest pulse velocity of the vibrational waves and compare each highest pulse velocity to a first reference pulse velocity, and a decision circuit including an artificial neural network configured to identify a compromised bond condition around a steel rod.

Abstract: Provided is a method of training a machine-learning-based artificial intelligence (AI) model to handle diverse types of motions occurring during image acquisition, including capturing image data including motion between an imaging device and tissue, modifying the captured image data, resulting in modified image data, by at least one of: altering an amount of time between any two frames; removing a subsequence of frames from the captured image data; and adding a subsequence of one or more new frames to the captured image data, and training a machine-learning-based AI model based on the modified image data. Other systems and methods are also described.

Abstract: Various examples are related to first person virtual reality (VR) characters suitable for testing of inclusive design solutions. In one example, a virtual reality (VR) system including a VR headset that can display a simulated VR environment to a user; controllers that can receive inputs from the user; and a computing device that can execute a VR application to simulate a VR character in the simulated VR environment, where the VR character simulates a physical impairment produced by a disability. Interactive first person VR characters with haptic capabilities operating in a simulated environment can provide feedback to the user that would not be available otherwise without physically constructing the environment.