Abstract: A stabilized formulation of triamcinolone acetonide in a bioadhesive base material is provided. The present invention further includes a method of producing a stabilized non-aqueous TAA formulation and methods of measuring the stability of such TAA formulations.

Abstract: An input-pattern aware reference generation system for a memory cell array having a plurality of word lines crossing a plurality of bit lines includes an input counting circuit, a reference array, and a reference word line control circuit. The input counting circuit receives the input signal of the memory cell array, discovers input activated word lines according to the input signal and generates a number signal representing a number of the input activated word lines. The reference array includes a plurality of reference memory cells storing a predetermined set of weights. The reference word line control circuit is electrically connected between the input counting circuit and the reference array. Moreover, the reference word line control circuit controls the reference array to generate a plurality of reference signals being able to distinguish candidates of the computational result of the bit lines in the memory cell array.

Abstract: Antennas suitable for use in compact radio frequency (RF) applications and devices, and methods of fabrication thereof. Described are resonator antennas, for example dielectric resonator antennas fabricated using polymer-based materials, such as those commonly used in lithographic fabrication of integrated circuits and microsystems. Accordingly, lithographic fabrication techniques can be employed in fabrication. The antennas have metal inclusions embedded in the resonator body which can be configured to control electromagnetic field patterns, which serves to enhance the effective permittivity of the resonator body, while creating an anisotropic material with different effective permittivity and polarizations in different orientations.

Abstract: The present disclosure provides compositions and methods for treating ocular disorders in mammals especially in and not limited to humans and mice. The present disclosure further provides methods of treating cancer and appetite suppression using the compositions which are novel small molecule inhibitors of CaMKK2. In addition, these derived compositions can regulate non-ocular disorders, such as cancer and appetite suppression by modulating and inhibiting CaMKK2 and the regulation of the macrophage mediated diseases.

Abstract: This invention relates, e.g., to a molecular delivery system comprising A. a substrate having a nanostructured surface region which comprises a plurality of nanostructures and, covalently attached to the substrate, multiple copies of a first member of a binding pair; and B. at least one vector nanoparticle which comprises, encapsulated therein, a molecule of interest, and on its surface, multiple copies of second member of the binding pair. Methods of using the molecular delivery system to deliver a molecule of interest to a cell are also described.

Abstract: The present invention discloses a cloud-oriented stream scheduling method based on Android platform, which aims to solve the problem that the calculation and storage capability of the mobile terminal device are limited and the application has a low expandability. The technical solution of the present invention is to build a core scheduling routine and an App management routine in a mobile terminal device based on Android operation system, and build a cloud management service subsystem in cloud server to construct a cloud-oriented stream scheduling system based on the Android platform to make the mobile terminal device enabled to dynamically install or uninstall the applications according to security attribute, user behavior habit, network status and transmission quality, processing capability of current mobile terminal device, and timed task of the application and achieve the consistent application view on the level of the mobile terminal device.

Abstract: According to some embodiments of the invention, a robot-assisted ultrasound system includes a first ultrasound probe, a robot comprising a manipulator arm having a tool end, and a second ultrasound probe attached to the tool end of the manipulator arm. The robot-assisted ultrasound system further includes a robot control system configured to control at least one of a position or a pose of the second ultrasound probe based on a contemporaneous position and pose of the first ultrasound probe, and an ultrasound processing and display system configured to communicate with at least one of the first and second ultrasound probes to receive and display an ultrasound image based on the first and second ultrasound probes acting in conjunction with each other.

Abstract: Bacterial resistance to antibiotics is increasing worldwide creating a global threat. Tuberculosis (TB), caused by the bacterium Mycobacterium tuberculosis, is a bacterial infectious disease that results in over one million deaths annually. The discovery outlined here involves a tablet composition for patient administration and subsequently a new paradigm in drug delivery vehicles in vivo and in vitro and is applied to existing TB antibiotics in order to increase their efficacy. The drug delivery system is a three component complex that is administered with the TB antibiotic or a combination of TB antibiotics. The components are a saccharide or saccharides, a transition metal ion or a combination of metal ions that can bind a nitrogen and/or oxygen atom(s), and a water soluble polymer capable of aggregating and enclosing the other constituents. The three component molecular delivery approach has demonstrated ability to overcome M. tuberculosis bacterial resistance to an existing antibiotic.

Abstract: Described generally herein are tissue therapy devices, which may comprise a sealant layer and a suction apparatus. The sealant layer functions so as to create a sealed enclosure between it and the surface of a patient by forming, preferably, an airtight seal around an area of tissue that requires negative pressure therapy. The tissue therapy device may comprise a suction apparatus. The suction apparatus is typically in fluid communication with the sealant layer and functions so as to reduce the amount of pressure present underneath the sealant layer. The reduced pressure is self-created by the suction apparatus. Together the sealant layer and the suction apparatus preferably create a closed reduced pressure therapy system. Preferably, the pressure under the sealant layer is reduced by expanding the volume of the enclosure space and thereby decreasing the density of the air molecules under the sealant layer.

Abstract: A method for preparing indenoisoquinoline derivatives represented by the following formula (I) is disclosed, which comprises the following steps: (A) providing a first reactant represented by the following formula (II) and a second reactant represented by the following formula (III): and (B) reacting the first reactant represented by the formula (II) and the second reactant represented by the formula (III) in a solvent and selectively adding R2NH2 therein, to obtain the indenoisoquinoline derivatives represented by the formula (I), wherein, R1, R2, R3, A, X, Y, Z, m and n are defined in the specification.

Abstract: An implantable hydrogel precursor composition can include: a cross-linkable polymer matrix that is biocompatible; and a plurality of polymer particles in the cross-linkable polymer matrix. The cross-linkable polymer matrix can include a cross-linkable hyaluronic acid polymer that has cross-linkable functional groups. The hyaluronic acid polymer can be a methacrylated hyaluronic acid polymer. The methacrylated hyaluronic acid polymer can have a molecular weight from about 500 kDa to about 1.8 MDa. The polymer particles can include a cross-linked hyaluronic acid. The cross-linkable polymer matrix having the polymer particles has a yield stress. The cross-linkable polymer matrix having the polymer particles has shape retention at physiological temperatures. The composition can include live cells in the cross-linkable polymer matrix. The composition can include a biologically active agent in the cross-linkable polymer matrix.

Abstract: The present invention relates to a method and device for sharing a candidate list. A method of generating a merging candidate list for a predictive block may include: producing, on the basis of a coding block including a predictive block on which a parallel merging process is performed, at least one of a spatial merging candidate and a temporal merging candidate of the predictive block; and generating a single merging candidate list for the coding block on the basis of the produced merging candidate. Thus, it is possible to increase processing speeds for coding and decoding by performing inter-picture prediction in parallel on a plurality of predictive blocks.

Abstract: A time synchronization method performed by a communication node in a vehicle includes: receiving, from a road side unit (RSU), a first frame including time information of a first domain to which the RSU belongs; setting a time of the vehicle based on a time indicated by the time information of the first domain; and transmitting a second frame including the time information of the vehicle.

Abstract: A method of reducing the level of a transcription product in a cell comprising contacting with the cell a composition comprising a double-stranded nucleic acid complex comprising a first nucleic acid strand annealed to a second nucleic acid strand, wherein: (i) the first nucleic acid strand hybridizes to the transcription product and comprises (a) a region consisting of at least 4 consecutive nucleotides that are recognized by RNase H when the strand is hybridized to the transcription product, (b) one or more nucleotide analogs located on 5? terminal side of the region, (c) one or more nucleotide analogs located on 3? terminal side of the region and (d) a total number of nucleotides and nucleotide analogs ranging from 8 to 35 nucleotides and (ii) the second nucleic acid strand comprises (a) nucleotides and optionally nucleotide analogs and (b) at least 4 consecutive RNA nucleotides.

Abstract: A biometric information detecting apparatus includes a bio-signal measurer including a light-emitting unit and a light-receiving unit, the light-emitting unit configured to emit an optical signal and the light-receiving unit configured to detect the optical signal that is modulated by a target object; a low-frequency signal obtainer configured to obtain a low-frequency signal from the bio-signal measured by the bio-signal measurer; and a signal processor configured to analyze biometric information from the bio-signal in response to determining that the low-frequency signal obtained from the bio-signal is within a reference range.

Abstract: A light scattering-based solar concentrator (LSSC) uses high refractive index nanoparticles (NPs) as dopants to selectively scatter photons across the solar spectrum without spectroscopic conversion by different sized nanoparticles. The LSSCs are limited by a single parameter: the surface photon losses, which can be addressed by nanofabrication to implement anti-reflective and light trapping structures into LSSC designs. The LSSC design provides solar concentrator techniques for photovoltaic (PV) applications.

Abstract: The present disclosure is generally directed to audio visualization methods for visual pattern recognition of sound. In particular, the present disclosure is directed to plotting amplitude intensity as brightness/saturation and phase-cycles as hue-variations to create visual representations of sound.

Abstract: A method of improving occluded edge quality in an augmented reality system includes a data input step of using a camera set to capture a scene and an object set in the scene to obtain an original image; an occluded region extracting step of obtaining an extracted image by performing a difference operation according to a first image and a second image, which are obtained according to depth buffer calculations according to first and second virtual planes set in the scene; and an occluded image generating step of inserting a virtual object into the original image according to the extracted image, the original image and a third virtual plane, which is set between the first and second virtual planes, to obtain an occluded image with a smoothened occluded edge.

Abstract: The present disclosure relates to multi-modality detection systems and methods. One illustrative multi-modality detection system may include a distributed radiation source configured to irradiate an object under detection, a primary collimator configured to separate rays of the distributed radiation source into two parts, wherein one part is for CT detection and the other part is for XRD detection, a CT detection device configured to perform a CT detection to acquire a CT image of the object under detection, and an XRD detection device configured to perform an XRD detection to acquire an XRD image of the object under detection, wherein the CT detection and the XRD detection are performed simultaneously.

Abstract: The disclosure provides a cell culturing article. The cell culturing article includes a substrate having a surface, a hydrophilic copolymer layer positioned on the surface of the substrate, and a plurality of peptide chains individually conjugated to a surface of the hydrophilic copolymer layer. The hydrophilic copolymer layer is copolymerized by a plurality of polyvinyl alcohol units, a plurality of polyvinyl alcohol derivative units, and a plurality of units containing at least one carboxyl group. A method for manufacturing the cell culturing article, a method for culturing undifferentiated stem cells and a method for regulating stem cell differentiation are also provided herein.