Abstract: Methods and systems for detecting a plume of a first fluid in a second fluid using an acoustic wave are provided, where the first fluid has a different acoustic index of refraction than the second fluid. A horizontal array having a plurality of receiving elements receives an acoustic signal propagated through the second fluid and at least one refracted signal refracted by the first fluid. The acoustic signal and the at least one refracted signal form a received signal. An interference pattern is detected from the received signal over the plurality of receiving elements. The interference pattern is due to interference between the acoustic signal and the at least one refracted signal. A horizontal angle of refraction is determined between the acoustic signal and the at least one refracted signal from the interference pattern. The horizontal angle of refraction is indicative of a physical characteristic of the first fluid.

Abstract: The present invention provides a method of hydroxylating or oxidizing a compound of interest in a subject (e.g., a cytotoxic oxazaphosphorine prodrug), by administering the compound of interest to the subject; and concurrently administering the subject a metalloporphyrin in an amount effective to hydroxylate or oxidize the compound of interest in the subject.

Abstract: The instant invention describes methods for producing macrocyclic compounds having antiproliferation activity, and useful in methods of treating disorders such as cancer, tumors and cell proliferation related disorders.

Abstract: An electronic device case includes a first shell, a second shell, and a side button. The first and second shells are each provided with a peripheral side plate. A passage communicating the inside and outside of the case, a first restriction slot extending from the passage toward the first shell, and a second restriction slot extending from the passage toward the second shell are formed jointly by the peripheral side plates of the shells embedded with each other. The side button is provided with a base and a press portion protruding from the base. The thickness of the base is larger than or equal to the widths of the restriction slots. The side button is installed in the passage with the base embedded in the restriction slots. As a result, the case is sufficiently water resistant, firm in structure and easy to assemble.

Abstract: An apparatus and methods for characterizing the response of a particle to a parameter that characterizes an environment of the particle. A change is induced in the parameter characterizing the environment of the particle, where the change is rapid on a timescale characterizing kinetic response of the particle. The response of the particle is then imaged at a plurality of instants over the course of a period of time shorter than the timescale characterizing the kinetic response of the particle. The response may be detected by measuring a temperature jump or by measuring correlation and anticorrelation between probe parameters across pixels. More particularly, the particle may be a molecule, such as a biomolecule, and the environment, more particularly, may be a biological cell. The parameter characterizing the environment of the particle may be a temperature, and change may be induced in the temperature by heating a volume that includes the particle, either conductively or radiatively.

Abstract: Provided is a method for adsorbing or separating carbon dioxide from a mixture of gases by passing the gas mixture through a porous three-dimensional polymeric coordination compound having a plurality of layers of two-dimensional arrays of repeating structural units, which results in a lower carbon dioxide content in the gas mixture. Thus, this invention provides useful compositions and methods for removal of greenhouse gases, in particular CO2, from industrial flue gases or from the atmosphere.

Abstract: An electrolyte composition with a low gelling temperature is disclosed, which includes: an electrolyte gelator which is an acrylonitrile-based copolymer; and a liquid electrolyte containing a nitrile-based solvent. A method for manufacturing an electronic device using the aforesaid electrolyte composition is also disclosed.

Abstract: The present invention relates generally to the fields of chemistry and radionuclide imaging. More particularly, it concerns compositions, kits and methods for imaging and therapy involving N4 compounds and derivatives.

Abstract: Systems, devices, and methods for measuring an under foot load profile of a patient during a period of partial weight bearing are described. The system may include a walking boot cast. A housing, including an inner surface and an upper surface that cooperate to define an inner cavity, may be oriented with respect to a patient's leg. The upper surface may be slidably received within the inner cavity in a piston and cylinder configuration or may be otherwise configured. The system may include a pressure sensor configured to monitor the load profile of a patient during the desired period of partial weight bearing. The pressure sensor may be located below the upper surface. The system may include a noncompressible force transmitter positioned within the inner cavity and at least partially encapsulating an upper portion of the pressure sensor to transmit pressure within the housing to the pressure sensor.

Abstract: A system 120 for reflecting or redirecting incident light, microwave or sound energy includes a first substrate 144 configured to support an array of reflective elements 130 that can be angularly displaced through a range of substantially 90 degrees in response to a reflector angle control signal and a controller programmed to generate the reflector angle control signal to achieve desired incident energy beam or wavefront re-direction. The reflective elements 130 preferably comprise MEMS micro-reflector elements hingedly or movably attached to the first substrate 130 and define a reflective surface that is aimed at the source of incident light, microwave or sound energy.

Abstract: A cyclized peptide designated BMP Binding Peptide (BBP) is a synthetic peptide that avidly binds rhBMP-2. BBP increases the overall osteogenic activity of rhBMP-2, increases the rate at which rhBMP-2 induces bone formation, and BBP induces calcification alone. Compositions and substrates including BBP, and methods of using BBP are useful in therapeutic, diagnostic and clinical applications requiring calcification and osteogenesis.

Abstract: The present invention provides a family of benzodiazepinone compounds and pharmaceutical compositions thereof. The present invention also provides methods of treating certain skin conditions, e.g., atopic dermatitis, rosacea, or psoriasis, by administering a benzodiazepinone and methods of reducing the proliferation of keratinocyte cells by exposing such cells to a benzodiazepinone.

Abstract: Multi-hop architectures of a wireless mesh network (WMN) compatible with the existing WiFi devices and potentially offering a much larger total capacity than a single-hop WiFi cell. The proposed architectures are scalable and do not have the hidden-terminal and the exposed-terminal problems intrinsic in a multi-hop environment that limited the space reuse efficiency of a WMN. The various disclosed architectures also support a fast and efficient location tracking scheme and can overcome the low space reuse efficiency in many of the existing WMN architectures.

Abstract: The present disclosure relates to a method for making a thermoacoustic element. In the method, a graphene film is arranged on a metal substrate. A nonmetal substrate is stacked with the graphene film located on the metal substrate to form a laminate structure. The graphene film is sandwiched between the nonmetal substrate and the metal substrate. The metal substrate is removed from the stacked structure. A number of through-holes are formed in the nonmetal substrate. The graphene film is exposed through the plurality of through-holes.

Abstract: Disclosed is a composition for preventing and treating acetaminophen induced liver injury including the protein extracted from Porphyra yezoensis. The protein(s), separated and purified from hot water extracts of Porphyra yezoensis, having the molecular weight of 14 kDa measured by sodium dodecyl sulfate polyacrylamide gel electrophoresis, has an excellent effect for inhibiting the oxidative injury of liver tissue and cell apoptosis of liver cells induced by acetaminophen.

Abstract: Described herein are methods of inhibiting or reversing the progression of cataract formation or presbyopia in an eye by administering a ?L-crystallin electrostatic interaction inhibitor. Both presbyopia and cataracts are caused by aggregation of the soluble crystalline lens proteins called the crystallins, particularly ?L-crystallin. It has been found that the aggregation of ?L-crystallin is an electrostatic phenomenon and that electrostatic interaction inhibitors can be employed to prevent the formation of ?L-crystallin aggregates as well as to deaggregate already formed aggregates.

Abstract: An apparatus is for detecting the presence of selected gaseous compounds indicative of a medical condition includes a probe having one or more sensor elements having a conductivity which is responsive to the presence of selected gaseous compounds, at least one sensor element containing a transition metal oxide selected from the group consisting of WO3, beta-MoO3 and UO2; and means for measuring the conductivity of each said sensor element.

Abstract: The invention discloses a wastewater processing method of hydrolysis-acidification enhanced by addition of zero-valent iron (ZVI), including the following steps: 3˜6 ZVI-filling layers are settled in the middle of an anaerobic hydrolysis-acidification reactor. Excess sludge taken from sewage treatment plant using as seed sludge is added into this anaerobic hydrolysis-acidification reactor for startup and domestication. In the present invention, ZVI are added into this anaerobic hydrolysis-acidification reactor to accelerate organic matters degradation and produce more acetic acids, accompanied with higher COD removal obtained. ZVI can be protected from rust in this anaerobic biological environment due to the air isolation. Also, ZVI can enhance anaerobic hydrolysis of wastewater through reducing refractory pollutants involved in wastewaters.

Abstract: The invention relates generally to methods and compositions for the cryopreservation and/or vitrification of tissue including articular cartilage and the preparation of said tissue for clinical or research use, including but not limited to joint replacement and the treatment and prevention of osteoarthritis.

Abstract: RNAi sequences that are useful as therapeutics in the treatment of cancers of various types, including prostate cancer, sarcomas such as osteosarcoma, renal cell carcinoma, breast cancer, bladder cancer, lung cancer, colon cancer, ovarian cancer, anaplastic large cell lymphoma and melanoma; and Alzheimer's disease. These sequences target clusterin, IGFBP-5, IGFBP-2, both IGFBP-2 and -5 simultaneously, Mitf, and B-raf. The invention further provides for the use of these RNAi sequences in the treatment of cancers of various types, including prostate cancer, sarcomas such as osteosarcoma, renal cell carcinoma, breast cancer, bladder cancer, lung cancer, colon cancer, ovarian cancer, anaplastic large cell lymphoma and melanoma; and Alzheimer's disease, and a method of treating such conditions through the administration of the RNA molecules with RNAi activity to an individual, including a human individual in need of such treatment.