Abstract: Disclosed are bioanodes comprising a quaternary ammonium treated NafionĀ® polymer membrane and a dehydrogenase incorporated within the treated NafionĀ® polymer. The dehydrogenase catalyzes the oxidation of an organic fuel and reduces an adenine dinucleotide. The ion conducting polymer membrane lies juxtaposed to a polymethylene green redox polymer membrane, which serves to electro-oxidize the reduced adenine dinucleotide. The bioanode is used in a fuel cell to produce high power densities.
Type:
Application
Filed:
October 8, 2009
Publication date:
February 18, 2010
Applicant:
St. Louis University
Inventors:
Shelley D. Minteer, Niki L. Akers, Christine M. Moore
Abstract: The present invention discloses a method for measuring the zeta potential at the cylinder's outer surface. In the measuring cell, the cylinder is held coaxially inside a reference tube and a given solution is forced to flow through the annular flow channel between the cylinder and the reference tube. The streaming potential induced by the flow forced with a hydraulic pressure drop is measured to determine the zeta potential, ?m, of the cylinder's outer surface by using the following Equation, E _ ? ? ? P == - D ? ? ? k ? ( ? m + ? ref 2 ) ? F where D is the permittivity, ?ref is the zeta potential of the reference tube, ? is the viscosity of the solution, k is the electric conductivity of the solution, and F is a correction factor for the electrokinetic model. Moreover, this invention also discloses a system for measuring the zeta potential of the cylinder's outer surface.
Abstract: The separation of single-walled carbon nanotubes (SWNTs), by chirality and/or diameter, using centrifugation of compositions of SWNTs in and surface active components in density gradient media.
Type:
Grant
Filed:
March 6, 2006
Date of Patent:
February 16, 2010
Assignee:
Northwestern University
Inventors:
Mark C. Hersam, Samuel I. Stupp, Michael S. Arnold
Abstract: Aspects of the present invention also provide methods based on novel UCN3 nucleotide polymorphisms selected from the group consisting of AAFC03043460.1:g.8272-8281AATAATAAAT(SEQ ID NO: 9)>GGAGC, g.8208C>T, g.8265C>T, g.8287T>C, g.8412A>G, g.8426T>A, c.8786C>T, g.9074T>C, c.12609C>T, c.12621T>C, c.12667T>G and c.12669C>A , which may provide novel markers for marbling and/or subcutaneous fat. Additional aspects provide for novel methods which may comprise marker-assisted selection or marker-assisted management to improve marbling and/or subcutaneous fat depth in cattle.
Type:
Grant
Filed:
November 15, 2007
Date of Patent:
February 16, 2010
Assignee:
Washington State University Research Foundation
Inventors:
Zhihua Jiang, Jennifer J. Michal, Galen A. Williams
Abstract: This invention provides a method for treating a subject having a tumor and a method for inhibiting angiogenesis in a subject, both comprising administering to the subject an effective amount of a composition of matter comprising the extracellular domain of a Notch receptor protein operably affixed to a half-life-increasing moiety. This invention also provides a composition of matter comprising the extracellular domain of Notch4 receptor protein operably affixed to a half-life-increasing moiety. This invention further provides an article of manufacture. Finally, this invention provides a replicable vector which encodes a polypeptide comprising the extracellular domain of a Notch receptor protein operably affixed to a half-life-increasing moiety, a host vector system which comprises such replicable vector and a method of producing such polypeptide.
Type:
Grant
Filed:
April 26, 2005
Date of Patent:
February 16, 2010
Assignee:
The Trustees of Columbia University in the City of New York
Inventors:
Jan Kitajewski, Carrie Shawber, Yasuhiro Funahashi
Abstract: Multilevel high power converters, referred to as hexagram converters, which preferably include a combination of six three-phase converter modules, are provided herein. The three-phase converter modules are interconnected and can be configured as any three-phase converter for any given application. One or more inductors can be used in the interconnections between the six modules to suppress potential circulating currents. Numerous applications exist in which the described converters can be implemented.
Type:
Grant
Filed:
August 27, 2007
Date of Patent:
February 16, 2010
Assignee:
The Regents of the University of Cailfornia
Abstract: The present invention provides ?-subunit-Associated Regulator of Apoptosis, or BARA, polypeptides and nucleic acid molecules encoding the same. The invention also provides selective binding agents, vectors, host cells, non-human transgenic animals, devices and methods for producing BARA polypeptides. The invention further provides compositions comprising BARA nucleic acids, polypeptides, and fusions or derivatives thereof. The invention further provides methods for treating, preventing, or ameliorating a medical disease, condition, or disorder comprising administering BARA or BARA compositions, as well as methods of diagnosing a pathological condition related to BARA. Still further, the invention provides methods of modulating levels of BARA expression and methods of determining whether a compound stimulates or inhibits BARA polypeptide activity or BARA polypeptide production.
Type:
Grant
Filed:
November 7, 2005
Date of Patent:
February 16, 2010
Assignee:
The Board of Trustees of the University of Illinois
Abstract: Phase matching high harmonic generation (HHG) uses a single, long duration non-collinear modulating pulse intersecting the driving pulse. A femtosecond driving pulse is focused into an HHG medium (such as a noble gas) to cause high-harmonic generation (HHG), for example in the X-ray region of the spectrum, via electrons separating from and recombining with gas atoms. A non-collinear pulse intersects the driving pulse within the gas, and modulates the field seen by the electrons while separated from their atoms. The modulating pulse is low power and long duration, and its frequency and amplitude is chosen to improve HHG phase matching by increasing the areas of constructive interference between the driving pulse and the HHG, relative to the areas of destructive interference.
Type:
Grant
Filed:
December 17, 2007
Date of Patent:
February 16, 2010
Assignee:
Rugents of the University of Colorado a body corporate
Inventors:
Oren Cohen, Henry C. Kapteyn, Margaret M. Mumane
Abstract: A method for silver staining a gel on which biological substances such as nucleic acids and proteins are separated by electrophoresis, which comprises at least the following steps: (a) the step of immersing an untreated gel after the electrophoresis in an aqueous solution of sodium thiosulfate; (b) the step of immersing the gel obtained in the step (a) in a mixture of ethanol and an aqueous solution of sodium acetate; and (c) the step of immersing the gel obtained in the step (b) in a mixture of ethanol and an aqueous solution of silver nitrate.
Abstract: The present invention provides recombinant polypeptides comprising an N-terminal fragment of an ActA protein or LLO protein fused to an antigen or a fragment thereof, nucleotides encoding same, recombinant vectors comprising same, and immunogenic and therapeutic methods utilizing same.
Type:
Grant
Filed:
March 13, 2006
Date of Patent:
February 16, 2010
Assignee:
The Trustees of the University of Pennsylvania
Abstract: A light emitting diode (LED) is provided. The LED at least includes a substrate, a saw-toothed multilayer, a first type semiconductor layer, an active emitting layer and a second type semiconductor layer. In the LED, the saw-tooth multilayer is formed opposite the active emitting layer below the first type semiconductor layer by an auto-cloning photonic crystal process. Due to the presence of the saw-tooth multilayer on the substrate of the LED, the scattered light form a back of the active emitting layer can be reused by reflecting and recycling through the saw-tooth multilayer. Thus, all light is focused to radiate forward so as to improve the light extraction efficiency of the LED. Moreover, the saw-tooth multilayer does not peel off or be cracked after any high temperature process because the saw-tooth multilayer has the performance of releasing thermal stress and reducing elastic deformation between it and the substrate.
Type:
Grant
Filed:
January 25, 2008
Date of Patent:
February 16, 2010
Assignees:
Industrial Technology Research Institute, National Tsing Hua University
Inventors:
Chen-Yang Huang, Hao-Min Ku, Shiuh Chao, Chu-Li Chao, Rong Xuan
Abstract: Indium oxide nanowires are used for determining information about different chemicals or Biologics. Chemicals are absorbed to the surface of the nanowires, and cause the semiconducting characteristics of the Nanowires to change. These changed characteristics are sensed, and used to determine either the presence of the materials and/or the concentration of the materials. The nanowires may be between 10 and 30 nm in diameter, formed using a comparable size particle of catalyst material. The nanowires may then be used as part of the channel of a field effect transistor, and the field effect transistor is itself characterized.
Abstract: A process for preparing a metal styrene polymer composite having nano metallic particles deposited thereon is disclosed, which includes a) undergoing free radical polymerization of styrene and an optional co-monomer in the presence of a persulfate initiator and a chain transfer agent; and b) contacting the resulting styrene oligomer or copolymer of styrene and the co-monomer from step a) with an aqueous solution containing a noble metal ion dissolved therein, so that the noble metal ion is reduced to element form particles and deposit on the styrene oligomer or copolymer of styrene and the co-monomer by sulfates on the oligomer or copolymer in the absence of a reducing agent.
Type:
Grant
Filed:
August 2, 2006
Date of Patent:
February 16, 2010
Assignee:
Chung Cheng Institute of Technology, National Defense University
Abstract: A micromachined artificial sensor comprises a support coupled to and movable with respect to a substrate. A polymer, high-aspect ratio cilia-like structure is disposed on and extends out-of-plane from the support. A strain detector is disposed with respect to the support to detect movement of the support.
Type:
Grant
Filed:
June 1, 2007
Date of Patent:
February 16, 2010
Assignee:
The Board of Trustees of the University of Illinois
Inventors:
Chang Liu, Jonathan Engel, Nannan Chen, Jack Chen
Abstract: The present invention relates to the construction of output stage of the Doherty amplifier and comprises a main amplifying unit, an auxiliary amplifying unit and a compact ?/4 line connecting two amplifying units. The compact ?/4 line connecting two amplifying units includes a first parallel capacitor grounded by being connected to the main amplifying unit in parallel; a second parallel capacitor grounded by being connected to the auxiliary amplifying unit in parallel; and an inductor or a microstrip transmission line connecting the main amplifying unit and the auxiliary amplifying unit. The Doherty amplifier in accordance with the present invention further comprises a matching network unit connecting to a final output by connecting the main amplifying unit and the auxiliary amplifying unit and; and a ?/4 line used as the voltage inputs of the main amplifying unit and the auxiliary amplifying unit.
Type:
Grant
Filed:
January 30, 2008
Date of Patent:
February 16, 2010
Assignee:
Sungkyunkwan University
Inventors:
Youngoo Yang, Hyun-Chul Park, Sung-Chan Jung
Abstract: The invention provides vitamin K-dependent polypeptides with enhanced membrane binding affinity. These polypeptides can be used to modulate clot formation in mammals. Methods of modulating clot formation in mammals are also described.
Abstract: Power-efficient, pulsed driving of capacitive loads to controllable voltage levels, with particular applicability to LCDs. Energy stored in a portion of the capacitive load is recovered during a recovery phase. Time-varying signals are used to drive the load and to recover the stored energy, thus minimizing power losses, using processes named adiabatic charging and adiabatic discharging.
Type:
Grant
Filed:
November 18, 2005
Date of Patent:
February 16, 2010
Assignee:
University of Southern California
Inventors:
Lars G. Svensson, William C. Athas, Rajat K. Lal
Abstract: A method of analysis including an intrinsically valid class of statistical methods for dealing with multivariate ordinal data. A decision support system that can (1) provide automated decision support in a transparent fashion (2) optionally be controlled by a decision maker, (3) provide for an evidence acquisition concept, including automatically increasing the content of an underlying database, and (4) provide a computationally efficient interactive distributed environment. The method is exemplified in the context of assisted diagnostic support.
Abstract: Disclosed is a substrate damage detection mechanism using Radio Frequency Identification (RFID) tag including a substrate, at least one RFID tag with a RFID chip, a RFID transmitter and at least one data input/output port and at least one conducting circuit loop arranged to cover the substrate and provided with a first end that is electrically connected to a reference voltage and a second end that is electrically connected to the data input/output port of the RFID tag. The RFID chip generates a conductive code when the conducting circuit loop is originally conducting and generates a open-circuit code when the conducting circuit loop becomes open circuit resulting from the damage of the substrate in which both the conductive code and the open-circuit code are transmitted by the RFID transmitter and received by a RFID reader to determine the damage of the substrate.
Abstract: The present invention is a method of determining breast cancer risk including the steps of establishing a risk probably value associated with a patient, the risk probability value calculated from an array of risk factors associated with breast cancer, applying a computer algorithm adapted to find abnormalities in the patient's mammogram, and increasing the tolerance level for false positive results in the computer algorithm responsive to a higher probability value associated with the patient and decreasing the tolerance level for false positive results in the computer algorithm responsive to a lower probability value associated with the patient.
Type:
Grant
Filed:
December 2, 2002
Date of Patent:
February 16, 2010
Assignee:
University of South Florida
Inventors:
John J. Heine, Robert P. Velthuizen, Jerry Alan Thomas