Abstract: There is provided a semiconductor device including a first channel-type first MISFET formed and a second channel-type second MISFET: a first source and a first drain of the first MISFET and a second source and a second drain of the second MISFET are made of the same conductive substance, and the work function ?M of the conductive substance satisfies at least one of relations respectively represented by (1) ?1<?M<?2+Eg2, and (2) |?M??1|?0.1 eV and |(?2+Eg2)??M|?0.1 eV, where ?1 represents an electron affinity of an N-type semiconductor crystal layer, and ?2 and Eg2 represent an electron affinity and a band gap of a crystal of a P-type semiconductor crystal layer.
Type:
Application
Filed:
December 6, 2013
Publication date:
April 3, 2014
Applicants:
Sumitomo Chemical Company, Limited, National Institute of Advanced Industrial Science And Technology, The University of Tokyo
Abstract: A point-of-care, screening kit for use by a heath care worker to create custom test strips for screening the bodily fluids of an individual for various, medical conditions includes: (a) a plurality of reagents (12), (b) a substrate (18) configured to: i) receive one of the reagents and react with it so as to cause it to acquire a first characteristic color, and, ii) upon the addition of the individual's bodily fluid to the substrate, acquire, as a result of the formulation of each of the reagents, a second, dichotomous characteristic color when the individual has a specific one of the various, medical conditions.
Type:
Application
Filed:
May 7, 2012
Publication date:
April 3, 2014
Applicant:
THE JOHNS HOPKINS UNIVERSITY
Inventors:
Sean Mongale, Shishira Nagesh, Ezra Taylor, Mary O'Grady, Thembi Mdluli, Peter Truskey, Sherri Hall, James Waring, III, Britni Crocker, Harshard Sanghvi, Elaine Yang, Soumyadipta Acharya, Maxim Budyansky, Matthew Means
Abstract: Compositions and methods related to stromal antigen 2 (STAG2) and its role in diverse human cancers, including nucleic acids, polypeptides, vectors, cells and cell lines.
Type:
Application
Filed:
November 25, 2013
Publication date:
April 3, 2014
Applicant:
Georgetown University
Inventors:
David SOLOMON, Jung-Sik Kim, Todd Waldman
Abstract: A method of evaluating tissue stiffness of a target area includes positioning an ultrasound elasticity imaging apparatus adjacent a surface of an area of tissue where the target area is located and applying a dynamic range of force to the tissue. A plurality of ultrasound beams can be directed at the tissue and a plurality of ultrasound echoes can be acquired from the strained tissue in the target area to calculate an amount of developed strain within the target area.
Type:
Application
Filed:
May 23, 2012
Publication date:
April 3, 2014
Applicants:
The Regents of the University of Michigan, University of Pittsburgh - Of the Commonwealth System of Higher Education
Inventors:
Kang Kim, Jingping Xu, Jonathan M. Rubin
Abstract: A heat pump system, including a main heat pump system and a directly expanded strong cool-heat radiation plate provided on the building surface and serving as the terminal of the main heat pump system. The directly expanded strong cool-heat radiation plate enables refrigerant in the main heat pump system to circulate therein. Since the heat pump system of the present application adopts the directly expanded strong cool-heat radiation plate as the terminal of the main heat pump system, refrigerant in the main heat pump system may exchange heat with air by means of the directly expanded strong cool-heat radiation plate directly, instead of secondary heat exchange of the refrigerant loop and the water circulation loop, thereby reducing loss in intermediate heat exchange, improving the heat exchange efficiency and heat utilization, and omitting the circulating pump for water circulation. An air-conditioner with the heat pump system is further disclosed.
Abstract: Systems and methods for inhibiting bone loss using FoxP3+ CD8 T-cells (TcREG). Osteoclasts are induced to produce FoxP3+ CD8 T-cells (TcREG) either in vivo or ex vivo. The FoxP3+ CD8 T-cells (TcREG) are provided to the patient to subsequently regulate osteoclast function, thereby establishing a bi-directional regulatory loop between osteoclasts and FoxP3+ CD8 T-cells(TcREG).
Type:
Application
Filed:
October 1, 2013
Publication date:
April 3, 2014
Applicant:
Saint Louis University
Inventors:
Rajeev Aurora, Zachary Buchwald, Jennifer Kiesel
Abstract: Implants for resurfacing or repairing one or more articular cartilage bearing surfaces of a biological organism include an engineered tissue and a biocompatible porous substrate secured to the engineered tissue for attaching the implant to a native bone of the biological organism. The engineered tissue includes a scaffold containing a biocompatible material, and a plurality of living chondrocytes supported by the scaffold. Methods for culturing chondrocytes for incorporation into a biocompatible implant are provided. A bioreactor for producing functional cartilaginous tissue from a cell-seeded scaffold and a system for producing functional cartilaginous tissue are also provided.
Type:
Application
Filed:
December 12, 2013
Publication date:
April 3, 2014
Applicants:
The Trustees of Columbia University in the City of New York, THE CURATORS OF THE UNIVERSITY OF MISSOURI
Inventors:
Clark T. Hung, Gerard A. Ateshian, Eric G. Lima, James L. Cook, Li Ming Bian
Abstract: The objective of the present invention is to provide a new compound which is effective in treating blood cancer, particularly multiple myeloma, and which is also effective in suppressing an SP cell, i.e. Side Population Cell, which is a cause of recurrence of cancer. The compound according to the present invention is a novel compound which has the specific benzylamine structure.
Abstract: A syringe press includes a housing, a compressible member, and a compression mechanism. The housing includes a longitudinal axis, a first end and a second end. The housing is configured to support a syringe, which includes a cylinder configured to contain a fluid, and a piston having a seal configured to move within the cylinder, between the first and second ends. The compressible member is supported by the housing between the first end and the piston. The compression mechanism is supported by the housing and is configured to apply a compressive force to the piston, the cylinder and the compressible member, between the first and second ends and along the longitudinal axis. The piston is driven into the cylinder, and fluid is driven through an output of the cylinder responsive to the compressive force.
Abstract: Systems, devices, and methods for delivering a biological material into an organelle of a cell are provided. In one aspect, for example, a method for introducing biological material into an organelle of a cell includes bringing into proximity a lance and a preselected biological material outside of a cell and charging the lance with a polarity and a charge sufficient to electrically associate the preselected biological material with a tip portion of the lance. The method also includes penetrating an outer portion of the cell with the lance and directing and inserting the lance into an organelle, discharging the lance to release at least a portion of the biological material into the organelle, and withdrawing the lance from the cell.
Type:
Application
Filed:
September 30, 2013
Publication date:
April 3, 2014
Applicant:
Brigham Young University
Inventors:
Quentin T. Aten, Sandra H. Burnett, Brian D. Jensen, Larry L. Howell
Abstract: Small molecule, peptidic hepatocyte growth factors mimics, which act as both mimetics and antagonists, have been generated. These molecules have been shown or predicted to have therapeutic potential for numerous pathologies including dementia, Alzheimer's disease, Parkinson's disease, amyotrphic lateral sclerosis, and other neurodegenerative diseases, spinal cord injury, traumatic brain injury, diabetes and metabolic syndrome, cancer, and defective wound healing.
Type:
Application
Filed:
March 14, 2013
Publication date:
April 3, 2014
Applicant:
WASHINGTON STATE UNIVERSITY
Inventors:
JOSEPH W. HARDING, JOHN W. WRIGHT, CAROLINE C. BENOIST, LEEN H. KAWAS, GARY A. WAYMAN
Abstract: A method for recovery of impurities and/or degradation products and/or heat-stable salts from amine-based solvents used for capture of C02 from gas streams. The method comprises recovering C02 from a C02-enriched amine-based solvent thereby producing a lean amine-based solvent, contacting and mixing together the lean amine-based solvent with a reaction composition comprising a phase-change catalyst and a diluent, thereby producing a first organic phase comprising the impurities and/or degradation products and/or heat-stable salts and a first aqueous phase comprising the lean amine-based solvent, separating the first organic phase and the first aqueous phase; and separately recovering the first organic phase and the first aqueous phase. The organic phase can be regenerated by intermixing with a NaOH solution to form an organic phase comprising therein the reaction composition and and an aqueous phase comprising the NaOH solution with the impurities and/or degradation products and/or heat-stable salts.
Abstract: One aspect provides a method of forming a mineralized material by co-culturing a epithelial cell, such as ameloblasts, and mesenchymal cells, such as osteoblasts or odontoblasts, in a mineral-stimulating medium. Another aspect provides matrix seeded with epithelial cells and mesenchymal cells and infused with a mineral-stimulating medium capable of forming a mineralized material in the matrix. Methods of manufacturing such compositions and methods of treating mineralization-related conditions are also provided.
Type:
Application
Filed:
October 3, 2011
Publication date:
April 3, 2014
Applicant:
The Trustees of Columbia University in the City of New York
Abstract: A photovoltaic panel system is reconfigurable. In another aspect, multiple photovoltaic modules are removably attachable in a linear manner via interfacing male and female electrical connectors and/or magnetic electrical connectors. A further aspect of the present system provides additive collective voltage increases by plugging in multiple photovoltaic modules along one axis while also providing additive collective current increases by connecting these and/or other photovoltaic modules along a generally perpendicular axis.
Type:
Application
Filed:
September 26, 2013
Publication date:
April 3, 2014
Applicant:
BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY
Abstract: A transgenic soybean plant harboring an exogenous nucleic acid molecule encoding porcine reproductive and respiratory syndrome virus ORF7 immunogen and methods for using the same to induce an antibody response and prevent a porcine reproductive and respiratory syndrome virus infection are provided.
Type:
Application
Filed:
October 2, 2013
Publication date:
April 3, 2014
Applicant:
The Board of Trustees of the University of Illinois
Abstract: The present invention provides a method and apparatus for fabricating piezoresistive polysilicon on a substrate by low-temperature metal induced crystallization by: (1) providing the substrate having a passivation layer; (2) performing, at or near room temperature in a chamber without breaking a vacuum or near-vacuum within the chamber, the steps of: (a) creating a metal layer on the passivation layer, and (b) creating an amorphous silicon layer on the metal layer, wherein the metal layer and the amorphous silicon layer have approximately the same thickness; (3) annealing the substrate, the passivation layer, the metal layer and the amorphous silicon layer at a temperature equal to or less than 600° C. and a period of time equal to or less than three hours to form a doped polysilicon layer below a residual metal layer; and (4) removing the residual metal layer to expose the doped polysilicon layer.
Type:
Application
Filed:
June 24, 2013
Publication date:
April 3, 2014
Applicant:
Board of Regents, The University of Texas System
Inventors:
Zeynep Celik-Butler, Suraj K. Patil, Donald Philip Butler
Abstract: The invention discloses an interactive simulated-globe display system including an imaging body, N image-projecting units, a data processing unit, an optical pointer, and M image-capturing units where N and M are respectively a natural number. The N image-projecting units project N images onto an external hemispheric surface of the imaging body. The N images constitute a hemi-globe image of a whole globe image. The data processing unit detects an indicated spot projected on the external hemispheric surface by the M image-capturing units, judges if a track relative to the indicated spot meets one of a plurality of position input rules, and if YES, executes an instruction corresponding to said one position input rule.
Abstract: In one aspect, the invention relates to substituted (E)-N?-(1-phenylethylidene)benzohydrazide analogs, derivatives thereof, and related compounds, which are useful as inhibitors of lysine-specific histone demethylase, including LSD1; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions to treat disorders associated with dysfunction of the LSD1. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
Type:
Application
Filed:
August 15, 2012
Publication date:
April 3, 2014
Applicant:
University of Utah Research Foundation
Inventors:
Hariprasad Vakayalapati, Venkataswamy Soma, Steven L. Warner, Bret Stephens, David J. Bearss, Sunil Sharma
Abstract: An equipment and method for forecasting tunnel water inrush using a magnetic resonance differential, where a computer is connected to a transmitting bridge circuit through a high voltage power supply, to a control unit, a first and second signal modulating circuits and a multi-channel collecting circuit; the control unit is connected to a transmitting driver circuit, a first and second protection switches, and the transmitting bridge circuit through the transmitting driver circuit; two ends of a transceiving multi-turn coil are connected to the multi-channel collecting circuit through the first and second protection switches; two ends of a receiving multi-turn coil are connected to the multi-channel collecting circuit through the second protection switch and the second signal modulating circuit; one end of the transceiving multi-turn coil is connected to the transmitting bridge circuit, and the other end is connected to the transmitting bridge circuit through a resonant capacitor.
Type:
Application
Filed:
May 17, 2012
Publication date:
April 3, 2014
Applicant:
JILIN UNIVERSITY
Inventors:
Yingji Wang, Jun Lin, Shuqin Sun, Chuandong Jiang, Jianpeng Wang, Bo Pang, Zhe Zhang