Abstract: The present invention relates to novel analogs of choline and methods of use or treatment of neurodegenerative disorders and/or conditions such as Parkinson's disease, Huntington disease, Alzheimer's disease and related disorders such as amyotrophic lateral sclerosis, spinal muscular atrophy, Friedrich's ataxia, Pick's disease, Bassen-Kornzweig syndrome, Refsom's disease, retinal degeneration, Cruetzfelt-Jacob syndrome or prion disease (mad cow disease), dementia with Lewy bodies, schizophrenia, paraneoplastic cerebellar degeneration and neurodegenerative conditions caused by stroke. The present compounds are effective to treat any neurological condition where acetylcholine transmission neurons and their target cells are affected.

Abstract: The disclosed invention relates to electrostatic spraying systems for liquids and specifically to an improved spray-charging nozzle system having increased reliability, consistency, safety and power efficiency for long-term operation in harsh agricultural and industrial applications. The invention achieves these advantages by: a) management of the interaction of any externally-originating electric fields with the droplet-charging electric-induction field being applied within the nozzle, including partial or total exclusion of the former fields; b) maintenance of the charge-induction electric field at the droplet-formation zone by precluding or minimizing leakage of charge in all directions from the induction electrode; c) protection of electronic and nozzle components from damage due to inadvertent overcurrents; and d) facilitation of non-tedious, convenient, trouble-free inspection and cleaning of the nozzle under harsh field conditions.