Abstract: The subject invention pertains to myricanol derivatives, therapeutic compositions, and methods for treatment of neurodegenerative diseases, in particular, neurodegenerative diseases associated with abnormal accumulation of protein tau.
Type:
Application
Filed:
April 8, 2013
Publication date:
February 19, 2015
Applicant:
Universtiy of South Florida
Inventors:
Chad Dickey, Umesh Jinwal, Laurent Calcul, Bill J. Baker
Abstract: This invention encompasses combination therapies including TCN, TCN-P, TCN-PM and/or related compounds and one or more additional anti-cancer agents, for example, taxanes a molecule that modulates the HER2/neu (erbB2) receptor, anthracyclin compounds, epidermal growth factor receptor inhibitor compounds, one or more platinum compounds and bortezomib and derivatives thereof and compositions with reduced toxicity for the treatment and prevention of tumors, cancer, and other disorders associated with abnormal cell proliferation.
Abstract: A submerged sensor head is protected from fouling by marine organisms by positioning the sensor head in a submerged hollow enclosure. Openings are formed in the hollow enclosure to admit water but filters are positioned in the openings so that only filtered water may enter the enclosure. The filters remove biologically active marine organisms from the water and have sufficient surface area to enable free flow of water into the hollow enclosure.
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