Patents Assigned to UNM Rainforest Innovations
  • Patent number: 10884007
    Abstract: A flow cytometry apparatus includes a flow cytometer having a suction or negative-pressure intake probe, a support for a microplate having a plurality of sample wells, and motive elements operatively connected to at least one of the probe and the support for moving the intake probe and the support relative to one another so that the intake probe is sequentially aligned with different sample wells of the microplate. The apparatus has no fluid pumping elements between the support and the flow cytometer so that a bubble-separated sample stream is forced to the flow cytometer solely by virtue of a negative pressure communicated via the intake probe.
    Type: Grant
    Filed: August 31, 2017
    Date of Patent: January 5, 2021
    Inventors: Bruce S. Edwards, Larry A. Sklar, Ronald D. Salesky
  • Patent number: 10864460
    Abstract: A variety of inorganic-organic hybrid materials and various methods for preparing and using the same are described. The hybrid materials are graphene or graphitic materials populated with organic molecules and may have a variety of surface defects, pits or three-dimensional architecture, thereby increasing the surface area of the material. The hybrid materials may take the form of three dimensional graphene nanosheets (3D GNS). If the organic molecules are enantiospecific molecules, the hybrid materials can be used for chiral separation of racemic mixtures.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: December 15, 2020
    Assignee: UNM Rainforest Innovations
    Inventors: Alexey Serov, Plamen B Atanassov, Nikolai Kalugin, Liliya V Frolova
  • Patent number: 10857130
    Abstract: The present invention relates to molecules which function as modulators (i.e., inhibitors and agonists) of the Ras-homologous (Rho) family of small GTPases (e.g. Rac, Cdc42 and Rho GTPases) and their use to treat diseases, including cancers (including solid tumors-medulloblastoma, ovarian, breast, head and neck, testicular, prostate among others and hematologic malignancies-B cell lymphoma, where these GTPases are overexpressed or hyperactivated), sporadic and genetic diseases where activation of Rho GTPases plays a pivotal role (Menkes disease, rheumatoid arthritis, atherosclerosis, diabetes (type I), Huntington's disease and Alzheimer's disease) which are mediated through these proteins. Compounds according to the present invention may also be used as a therapy for the treatment of Entamoeba spp. or Acanthamoeba spp. infections, especially including Entamoeba histolytica.
    Type: Grant
    Filed: February 28, 2017
    Date of Patent: December 8, 2020
    Assignee: UNM Rainforest Innovations
    Inventors: Angela Wandinger-Ness, Laurie Hudson, Larry Sklar, Zurab Surviladze, Tudor Oprea
  • Patent number: 10837139
    Abstract: Provided are polymer-aerogel composite coatings, devices and articles including polymer-aerogel composite coatings, and methods for preparing the polymer-aerogel composite. The exemplary article can include a surface, wherein the surface includes at least one region and a polymer-aerogel composite coating disposed over the at least one region, wherein the polymer-aerogel composite coating has a water contact angle of at least about 140° and a contact angle hysteresis of less than about 1°. The polymer-aerogel composite coating can include a polymer and an ultra high water content catalyzed polysilicate aerogel, the polysilicate aerogel including a three dimensional network of silica particles having surface functional groups derivatized with a silylating agent and a plurality of pores.
    Type: Grant
    Filed: December 28, 2015
    Date of Patent: November 17, 2020
    Inventors: David J. Kissel, Charles Jeffrey Brinker
  • Patent number: 10836638
    Abstract: The present invention provides a novel solution or route for metal phosphide (MPx) nanomaterials from the thermal decomposition of metal bis[bis(diisopropylphosphino)amide], M[N(PPri2)2]2, and/or single-source precursors. Synthetic routes to MPx nanomaterials may be used in energy applications including batteries, semiconductors, magnets, catalyst, lasers, inks, electrocatalysts and photodiodes.
    Type: Grant
    Filed: April 8, 2016
    Date of Patent: November 17, 2020
    Assignee: UNM Rainforest Innovations
    Inventors: Richard Alan Kemp, Diane Dickie, Bernadette A. Hernandez-Sanchez, Timothy N. Lambert
  • Patent number: 10827946
    Abstract: The present invention concerns a method for determining whether brain regions of interest having reversible or irreversible pathology. The method includes acquiring over a predetermined period of time a plurality of magnetic resonance imaging (MRI) images for each brain region of interest; analyzing the MRI images to obtain quantitative measurements of the fractional anisotropy (FA) for each brain region of interest and determining that brain regions of interest have reversible pathology when the measured FA increases and then decreases over the predetermined period of time.
    Type: Grant
    Filed: August 31, 2016
    Date of Patent: November 10, 2020
    Assignee: UNM Rainforest Innovations
    Inventors: Shihoko Kimura-Ohba, Laurel Sillerud
  • Patent number: 10821167
    Abstract: The present invention is directed to virus-like particles (VLPs) which are engineered to present epitopes from Staphylococcus aureus (SA), preferably autoinducing peptides (AIPs) which regulate quorum-sensing dependent virulence in this pathogen, or epitopes from SA toxins and leukocidins. These VLPs may be used to provide immunogenic compositions and efficacious vaccines. In a mouse model of SA dermonecrosis, vaccination with AIP-containing VLPs or SA toxin-containing VLPs induces protective immunity to limit the pathogenesis of SA infection and promote bacterial clearance.
    Type: Grant
    Filed: February 1, 2017
    Date of Patent: November 3, 2020
    Assignee: UNM Rainforest Innovations
    Inventors: Pamela Hall, Bryce Chackerian, David S. Peabody, Seth Michael Daly, Bradley Owen Elmore, Kathleen Triplett
  • Patent number: 10826109
    Abstract: Novel non-planar non-contiguous graphene structures and novel methods for forming the same. According to some embodiments the novel methods result in three-dimensional graphene structures. According to a further embodiment these three-dimensional graphene structures have a specific, controlled morphology. According to a still further method the novel method results in decoratable graphene sheets or three-dimensional graphene structures.
    Type: Grant
    Filed: July 1, 2014
    Date of Patent: November 3, 2020
    Assignee: UNM Rainforest Innovations
    Inventors: Alexey Serov, Plamen B Atanassov, Nalin Andersen
  • Patent number: 10813175
    Abstract: An optoelectronic device having a self-defrosting/de-icing window configured to operate at an electromagnetic radiation frequency having metals that are optically transparent as a result of the wires having an effective plasma frequency that is equal to or lower than the electromagnetic frequency at which the device operates. The effective plasma frequency of the wire is lowered by configuring the path of the wire between the terminal ends to be meandering, serpentine, U-shaped and in other non-linear configurations. The metal wires are resistively heated.
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: October 20, 2020
    Assignee: UNM Rainforest Innovations
    Inventor: Sang Eon Han
  • Patent number: 10792304
    Abstract: Methods and compositions for the treatment, amelioration, or prevention of cancer and/or cancer metastasis by delivery of a hemodynamics altering agent such as a drag reducing polymer (DRP).
    Type: Grant
    Filed: February 15, 2019
    Date of Patent: October 6, 2020
    Assignees: UNM Rainforest Innovations, University of Pittsburgh
    Inventors: Marina V. Kameneva, Denis Bragin, Edwin Nemoto, Richard Simmons
  • Patent number: 10770861
    Abstract: A light-emitting device having a self-cooled semiconductor laser having a laser cavity.
    Type: Grant
    Filed: May 15, 2019
    Date of Patent: September 8, 2020
    Assignee: UNM Rainforest Innovations
    Inventors: Marek Osinski, Gennady A. Smolyakov