Abstract: A process for the specific isotopic labeling of an amino acid selected from Valine (Val), Leucine (Leu), and Isoleucine (Ile), in proteins and biomolecular assemblies by introducing, in a medium containing bacteria overexpressing a protein, an acetolactate derivative of Formula I of the application.
Type:
Application
Filed:
June 13, 2017
Publication date:
September 28, 2017
Applicants:
COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNVERSITE JOSEPH FOURIER
Inventors:
Pierre GANS, Jerome BOISBOUVIER, Isabel AYALA, Olivier HAMELIN