Abstract: A method of using microfluidic chips to significantly accelerate the time to identify and quantify microbes in a biological sample and test them for antibiotic resistance, particularly for urinary tract infections. A first microfluidic chip uses antibody or similar probes to identify and quantify any microbes present. The same or a similar chip uses antibody or similar probes to identify microbes with DNA or RNA known to indicate antibiotic resistance. Another microfluidic chip tests for antibiotic susceptibility of any microbes by growing them in very small wells in the presence of antibiotics, reducing the time required for such testing by as much as 95%. Another microfluidic chip runs traditional urinalysis or similar tests.
Type:
Application
Filed:
July 23, 2020
Publication date:
January 28, 2021
Applicant:
Urinary Technologies, Inc.
Inventors:
Michael D. FINCH, Kee Onn FONG, Saurabh KOTIAN, Cyrus B. MUNSHI, Advitiya MAHAJAN, Beth A. LINDBORG
Abstract: Several microfluidic chips are used to significantly accelerate the time to identify and quantify microbes in a biological sample and test them for antibiotic resistance, particularly for urinary tract infections. A first microfluidic chip uses antibody or similar probes to identify and quantify any microbes present. The same or a similar chip uses antibody or similar probes to identify microbes with DNA or RNA known to indicate antibiotic resistance. Another microfluidic chip tests for antibiotic susceptibility of any microbes by growing them in very small wells in the presence of antibiotics, reducing the time required for such testing by as much as 95%. Another microfluidic chip runs traditional urinalysis or similar tests.
Type:
Grant
Filed:
August 26, 2019
Date of Patent:
August 11, 2020
Assignee:
Urinary Technologies, Inc.
Inventors:
Michael D. Finch, Kee Onn Fong, Saurabh Kotian, Cyrus B. Munshi, Advitiya Mahajan, Beth A. Lindborg
Abstract: Several microfluidic chips are used to significantly accelerate the time to identify and quantify microbes in a biological sample and test them for antibiotic resistance, particularly for urinary tract infections. A first microfluidic chip uses antibody or similar probes to identify and quantify any microbes present. The same or a similar chip uses antibody or similar probes to identify microbes with DNA or RNA known to indicate antibiotic resistance. Another microfluidic chip tests for antibiotic susceptibility of any microbes by growing them in very small wells in the presence of antibiotics, reducing the time required for such testing by as much as 95%. Another microfluidic chip runs traditional urinalysis or similar tests.
Type:
Application
Filed:
August 26, 2019
Publication date:
March 5, 2020
Applicant:
Urinary Technologies, Inc.
Inventors:
Michael D. FINCH, Kee Onn FONG, Saurabh KOTIAN, Cyrus B. MUNSHI, Advitiya MAHAJAN, Beth A. LINDBORG