Abstract: The invention relates to a tissue transplant construct for the reconstruction of a human or animal organ. The tissue transplant construct (5) comprises (a) a membrane composite (1) comprising at least a first biocompatible, collagen-containing membrane (2) and a second biocompatible, collagen-containing membrane (3), wherein the first membrane (2) and the second membrane (3) are adjacent to each other at their flat sides, and wherein the first membrane (2) is of equine or bovine origin and the second membrane (3) is of animal or human origin and the second membrane (3) is of another origin than the first membrane (2); and (b) one or more layers (4) of mucosa tissue cells on one or both outer flat sides of the membrane composite (1).