Abstract: The present invention relates to a salt of formula (I), the preparation method for preparing same, and the use thereof in the preparation of silodosin.
Type:
Grant
Filed:
September 29, 2016
Date of Patent:
September 24, 2019
Assignee:
URQUIMA S.A.
Inventors:
José Luis Del Río Pericacho, Xavier Vila Tusell
Abstract: A method for the preparation of purified ivabradine and salts thereof, a method for the purification of ivabradine and salts thereof, a new reactant used in said methods and the use of said reactant for the preparation of ivabradine.
Type:
Grant
Filed:
June 2, 2016
Date of Patent:
March 5, 2019
Assignee:
URQUIMA, S.A.
Inventors:
José Luis Del Río Pericacho, Yolanda Arredondo Martínez
Abstract: A method for the preparation of purified ivabradine and salts thereof, a method for the purification of ivabradine and salts thereof, a new reactant used in said methods and the use of said reactant for the preparation of ivabradine.
Type:
Application
Filed:
June 2, 2016
Publication date:
June 14, 2018
Applicant:
URQUIMA, S.A
Inventors:
José Luis DEL RÍO PERICACHO, Yolanda ARREDONDO MARTÍNEZ
Abstract: Ivabradine hydrochloride Form IV, its pharmaceutical composition, process for its preparation, and its use as therapeutically active ingredient and pharmaceutical compositions containing Ivabradine hydrochloride Form IV.
Type:
Grant
Filed:
July 22, 2015
Date of Patent:
April 12, 2016
Assignee:
URQUIMA, S.A.
Inventors:
Rafael Prohens Lopez, Cristina Puigjaner Vallet, Rafael Barbas Canero, Jose Luis Del Rio Pericacho, Josep Marti Via
Abstract: Ivabradine hydrochloride Form IV, its pharmaceutical composition, process for its preparation, and its use as therapeutically active ingredient and pharmaceutical compositions containing lvabradine hydrochloride Form IV.
Type:
Application
Filed:
July 22, 2015
Publication date:
December 3, 2015
Applicant:
URQUIMA, S.A.
Inventors:
Rafel Prohens Lopez, Cristina Puigjaner Vallet, Rafael Barbas Canero, Jose Luis Del Rio Pericacho, Josep Marti Via
Abstract: Ivabradine hydrochloride Form IV, its pharmaceutical composition, process for its preparation, and its use as therapeutically active ingredient.
Type:
Grant
Filed:
September 21, 2012
Date of Patent:
September 22, 2015
Assignee:
URQUIMA, S.A.
Inventors:
Rafel Prohens Lopez, Cristina Puigjaner Vallet, Rafael Barbas Canero, Jose Luis Del Rio Pericacho, Josep Marti Via
Abstract: Process for the preparation of olopatadine (I), which comprises reacting a compound of formula (V) in the presence of a palladium catalyst to provide a compound of formula (VI), wherein the acid protecting group is removed to provide the compound of formula (I) and if desired, transformation into its salts.
Type:
Grant
Filed:
July 11, 2005
Date of Patent:
November 3, 2009
Assignee:
Urquima S.A.
Inventors:
Joan Bosch Cartés, Jordi Bachs Roca, Antonia Ma Gomez Gomez, Yolanda Alonso Marin, Mercè Bessa Sanchez
Abstract: A new process for the preparation of Ropinirole (1) and pharmaceutically acceptable hydrochloride salt thereof comprising reacting the compound (V) with nitromethane to obtain the compound of formula (II), which is reduced to compound (III) and alkylated to obtain compound (IV).
Type:
Grant
Filed:
October 13, 2004
Date of Patent:
June 12, 2007
Assignee:
Urquima S.A.
Inventors:
Joan Bosch Cartés, Xavier Pujol Ollé, José Luis Del Rio Pericacho, Yolanda Alonso Marin, Mercè Bessa Sanchez
Abstract: Thaumatins, protein sweeteners, are obtained through the expression of artificial, synthetic and substantially optimized genes, preferably in filamentous fungi such as Penicillium roquefortii, Aspergillus niger and Aspergillus niger var. awamori. Preparing substantially optimized artificial genes allows for high protein expression, making the process useful for industrial production of this valuable sweetener. Thaumatins may be obtained extracellularly and intracellularly. Intracellular production provides thaumatin-containing fungi that can be used per se in animal feed without prior separation of the fungal mycelium.
Type:
Grant
Filed:
April 21, 1995
Date of Patent:
August 3, 1999
Assignee:
Urquima, S.A.
Inventors:
Juan Uriach-Marsal, Victor Rubio-Susan, Cristina Patino-Martin, Eliza Iossif Kalo-Koenova, Catalina del Moral-Juarez, Ignacio Faus-Santasusana, Jose-Luis del Rio-Pericacho, Joan Blade-Pique