Patents Assigned to Ursapharm Arzneimittel GmbH
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Publication number: 20250032412Abstract: The present invention relates to a self-emulsifying oil-in-water microemulsion or nanoemulsion, containing or consisting of at least one surface-active antioxidant, at least one zwitterionic substance, and at least one active substance. The active substance can be effectively emulsified even in the case of low water solubility, and therefore its bioavailability is significantly increased. In many cases, the improved bioavailability means that the active substance concentration can be accordingly reduced and the biocompatibility can be increased as a result. The present invention also relates to an emulsifying composition, by means of which active substances can be effectively emulsified.Type: ApplicationFiled: November 11, 2022Publication date: January 30, 2025Applicant: URSAPHARM ARZNEIMITTEL GMBHInventors: Ute STEINFELD, Hyeck HEE LEE, Frank HOLZER, Markus MAHLER
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Publication number: 20240216484Abstract: The present invention addresses the problem of indicating active-ingredient classes which can treat virus diseases caused by coronaviruses in a human or animal. Said treatment includes the acute treatment of an already existing virus disease and the prophylaxis of same. The present invention relates to a bromelain protease, bromelain, jacalin-like lectin, extract from the stem and/or the fruit of a pineapple plant, combination preparation, bromelain protease inhibitor, protein/protease mix, and glycated bromelain protein formed by exogenous non-enzymatic glycation, for use in the treatment or prophylaxis of virus infections caused by coronaviruses in a human or animal.Type: ApplicationFiled: June 10, 2021Publication date: July 4, 2024Applicants: URSAPHARM ARZNEIMITTEL GMBH, HOCHSCHULE KAISERSLAUTERN, HELMHOLTZ-INSTITUT FÜR PHARMAZEUTISCHE FORSCHUNG SAARLANDInventors: Peter GROSS, Rolf MÜLLER, Frank HOLZER, Peter MEISER, Holger SEELERT
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Patent number: 11707484Abstract: The invention relates to a food supplement containing minerals and/or vitamins, a humectant and, for example, essential oils. The food supplement is formulated as an oral spray. In particular, the invention relates to a concentrated food supplement in the form of an oral spray, containing a combination of magnesium ions, panthenol (vitamin B5), caffeine, menthol aroma and/or peppermint aroma, and a humectant. The food supplement is particularly suited for use in sport and in stressful situations.Type: GrantFiled: January 14, 2019Date of Patent: July 25, 2023Assignee: URSAPHARM ARZNEIMITTEL GMBHInventors: Ute Steinfeld, Dominik Holzer
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Publication number: 20210052636Abstract: The invention relates to a food supplement containing minerals and/or vitamins, a humectant and, for example, essential oils. The food supplement is formulated as an oral spray. In particular, the invention relates to a concentrated food supplement in the form of an oral spray, containing a combination of magnesium ions, panthenol (vitamin B5), caffeine, menthol aroma and/or peppermint aroma, and a humectant. The food supplement is particularly suited for use in sport and in stressful situations.Type: ApplicationFiled: January 14, 2019Publication date: February 25, 2021Applicant: URSAPHARM ARZNEIMITTEL GMBHInventors: Ute STEINFELD, Dominik HOLZER
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Immune stimulating composition comprising an extract of sp. in combination with selenium and/or zinc
Patent number: 10293014Abstract: Disclosed is a composition which comprises a combination of Aronia extract in an amount of at least about 10 ?g/mg and seleniumin in an amount from about 0.0001 ?g/mg to about 2.0 ?g/mg. The composition may further comprise zinc as additional micronutrient. The composition may be formulated as a pharmaceutical or a nutraceutical composition.Type: GrantFiled: January 20, 2015Date of Patent: May 21, 2019Assignee: Ursapharm Arzneimittel GmbHInventors: Klaus Eschmann, Josef Beuth -
Publication number: 20140301875Abstract: The invention relates to a metering pump for a metering device for metered dispensing of a liquid, which can be connected to a storage container, comprising a cylindrical pump body and an actuation body.Type: ApplicationFiled: October 20, 2011Publication date: October 9, 2014Applicant: Ursapharm Arzneimittel GmbHInventors: Hyeck-Hee Lee, Ute Steinfeld, Frank Holzer, Markus Mahler
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Patent number: 8648057Abstract: The invention relates to a pharmaceutical composition free from dexpanthenol, calcium ions and phosphate, comprising at least one calcium chelating agent and at least one opthalmologically compatible viscosity regulator and optionally one or more pharmaceutical excipients. The invention further relates to the use of a calcium chelating agent and an opthalmologically compatible viscosity regulator for the production of a phosphate-free pharmaceutical composition for the treatment and/or prevention of epithelial defects.Type: GrantFiled: November 17, 2006Date of Patent: February 11, 2014Assignee: Ursapharm Arzneimittel GmbH & Co. KGInventors: Frank Holzer, Dorothea Gross
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Patent number: 8409840Abstract: The present invention pertains in general to Bromelain and particularly to the different active compounds contained in this complex mixture of proteins. The present invention provides recombinant expressed cysteine proteases, which are found in Bromelain. It has been found that the method for expression of the recombinant proteins is superior to the purification from Bromelain itself.Type: GrantFiled: August 8, 2008Date of Patent: April 2, 2013Assignee: Ursapharm Arzneimittel GmbHInventors: Rolf Müller, Nora Luniak, Klaus Eschmann
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Publication number: 20120148683Abstract: It pertains to a composition which comprises a combination of Aronia extract in an amount of at least about 10 ?g/mg and seleniumin in an amount from about 0.0001 ?g/mg to about 2.0 ?g/mg. The composition may further comprise zinc as additional micronutrient. The composition may be formulated as a pharmaceutical or a nutraceutical composition.Type: ApplicationFiled: May 6, 2010Publication date: June 14, 2012Applicant: URSAPHARM ARZNEIMITTEL GMBHInventors: Klaus Eschmann, Josef Beuth
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Publication number: 20120122976Abstract: The invention relates to a phosphate-free pharmaceutical composition which comprises at least one FP prostanoid receptor agonist and/or at least one prostamide receptor agonist and also citrate salts and/or citric acid.Type: ApplicationFiled: May 14, 2010Publication date: May 17, 2012Applicant: URSAPHARM ARZNEIMITTEL GMBHInventor: Frank Holzer
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Publication number: 20110200541Abstract: The present invention pertains in general to Bromelain and particularly to the active compounds contained in this complex mixture of proteins. The present invention provides recombinant expressed Bromelain inhibitor precursor and Bromelain inhibitors, which are found in Bromelain. It has been found that the recombinant expressed inhibitors have superior effects in terms of treatment of disorders and conditions than Bromelain or its protein fractions from plant extracts.Type: ApplicationFiled: July 27, 2009Publication date: August 18, 2011Applicant: Ursapharm Arzneimittel GmbHInventors: Rolf Müller, Nora Luniak, Klaus Eschmann
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Publication number: 20100272659Abstract: The present invention pertains in general to Bromelain and particularly to the different active compounds contained in this complex mixture of proteins. The present invention provides recombinant expressed cysteine proteases, which are found in Bromelain. It has been found that the method for expression of the recombinant proteins is superior to the purification from Bromelain itself.Type: ApplicationFiled: August 8, 2008Publication date: October 28, 2010Applicant: URSAPHARM ARZNEIMITTEL GMBHInventors: Rolf Müller, Nora Luniak, Klaus Eschmann
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Patent number: 7731958Abstract: The present application pertains to the use of bromelain preparing a medicament for increasing the IL-(8) level in an individual so as to reduce or prevent inflammation in said individual and as an adjuvant therapy during wound healing processes.Type: GrantFiled: November 28, 2001Date of Patent: June 8, 2010Assignee: Ursapharm Arzneimittel GmbH & Co. KGInventors: Rainer Maurer, Klaus Eschmann
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Patent number: 7279173Abstract: A microbicidally coated article, especially a container, having on at least part of it a coating comprising an organically modified inorganic matrix comprising silver colloids which is obtainable by application of a coating composition comprising a) a hydrolysate or condensate based on at least one hydrolysable silane with at least one non-hydrolysable substituent and b) a silver compound to the surface of the article and treatment with heat and/or radiation to form the silver colloid coating. Articles coated in accordance with the invention are therefore particularly suitable for purposes of disinfection, preservation, cosmetic, pharmaceutical or medical purposes. Articles from the pharmaceutical or medical sector, especially containers for pharmaceuticals or articles or components which come into contact with the human body and are required to be free from germs, are preferred fields of application.Type: GrantFiled: July 13, 2001Date of Patent: October 9, 2007Assignees: Leibniz-Institut Fuer Neue Materialien Gemeinnuetzige GmbH, Ursapharm Arzneimittel GmbH & Co. KGInventors: Thomas Schiestel, Hermann Schirra, Helmut Schmidt, Detmar Buxmann
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Patent number: 7249693Abstract: A fluid dispenser for germ-free fluid is described incorporating at least one material being capable of interacting via an oligodynamically active substance. The dispenser includes a metering pump and inlet and outlet valves. The fluid coming into contact with at least one oligodynamically active substance is present in the region of the outlet valve, of the inlet thereto and/or the outlet therefrom.Type: GrantFiled: December 22, 2004Date of Patent: July 31, 2007Assignee: Ursapharm Arzneimittel GmbH & Co. KGInventor: Detmar Buxmann
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Publication number: 20060058345Abstract: The invention concerns the use of papaverine-like vasodilator for the production of a pharmaceutical composition for the treatment of ophthalmological dysfunctions which are linked to circulatory disturbances of the eye or which are to be attributed to circulatory disturbances of the eye, wherein the pharmaceutical composition is to be applied topically to the eye. The invention further concerns a pharmaceutical composition which includes papaverine-like vasodilator and pharmacologically compatible viscosity regulator.Type: ApplicationFiled: August 8, 2003Publication date: March 16, 2006Applicant: Ursapharm Arzneimittel GmbH & Co KGInventors: Dorothea Gross, Frank Holzer
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Publication number: 20050173459Abstract: A fluid dispenser for germ-free fluid is described incorporating at least one material being capable of interacting via an oligodynamically active substance. The dispenser includes a metering pump and inlet and outlet valves. The fluid coming into contact with at least one oligodynamically active substance is present in the region of the outlet valve, of the inlet thereto and/or the outlet therefrom.Type: ApplicationFiled: December 22, 2004Publication date: August 11, 2005Applicant: Ursapharm Arzneimittel GmbH & Co. KGInventor: Detmar Buxmann
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Publication number: 20040200860Abstract: A fluid dispenser for germ-free fluid is described incorporating at least one material being capable of interacting via an oligodynamically active substance. The dispenser includes a metering pump and inlet and outlet valves. The fluid coming into contact with at least one oligodynamically active substance is present in the region of the outlet valve, of the inlet thereto and/or the outlet therefrom.Type: ApplicationFiled: April 15, 2003Publication date: October 14, 2004Applicant: Ursapharm Arzneimittel GmbH & Co. KGInventor: Detmar Buxmann
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Patent number: 6803038Abstract: The present invention relates to the use of bromelaine proteases for inhibiting blood coagulation, especially for stimulating the production of plasmin, for inhibiting the production of fibrin and for inhibiting the adhesion of human thrombocytes on endothelilum cells. Especially the basic proteases isolable from raw bromelaine have proved to be particularly suitable proteases.Type: GrantFiled: July 25, 2001Date of Patent: October 12, 2004Assignee: Ursapharm Arzneimittel GmbHInventors: Rainer Maurer, Klaus Eckert, Edyta Grabowska, Klaus Eschmann
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Patent number: 5614172Abstract: In a fluid dispenser for germ-free fluid, in particular eye-drops, the delivery passage from a supply container contains an oligodynamically germicidally active substance that is soluble in the fluid. Said device comprises a metering pump operating without air pressure compensation and having an inlet valve for closing the inlet opening from said container and said fluid-soluble oligodynamically germicidally active substance is situated in the region of said inlet valve or of the inlet thereto and/or the outlet therefrom.Type: GrantFiled: February 24, 1995Date of Patent: March 25, 1997Assignee: URSAPHARM Arzneimittel GmbHInventor: Gunter Geimer