Abstract: The invention is a system and method for automatic acoustic speaker adaptation in an automatic speech recognition assisted transcription system. Partial transcripts of audio files are generated by a transcriptionist. A topic language model is generated from the partial transcripts. The topic language model is interpolated with a general language model. Automatic speech recognition is performed on the audio files by a speech recognition engine using a speaker independent acoustic model and the interpolated language model to generate semi-literal transcripts of the audio files. The semi-literal transcripts are then used with the corresponding audio files to generate a speaker dependent acoustic model in an acoustic adaptation engine.