Patents Assigned to Usbiomaterials Corporation
  • Patent number: 6743513
    Abstract: The invention described herein is a bioactive composite material comprising thin layers of bioactive glass reinforced with thin ductile metallic layers, and the use of this material in bone replacement procedures.
    Type: Grant
    Filed: September 20, 2001
    Date of Patent: June 1, 2004
    Assignee: USBiomaterials Corporation
    Inventors: John J. Mechlosky, Jr., Zheng Chen, Daniel Clupper
  • Patent number: 6517863
    Abstract: Compositions and methods for treating nails and adjacent tissues are disclosed. The compositions include non-interlinked particles of bioactive glass, alone or in combination with therapeutic agents, hydrophilic polymers, and other optional components. The compositions optionally include an appropriate aqueous carrier for topical administration. The methods involve applying an effective nail-enhancing amount of the composition to the nails and adjacent tissues for a sufficient amount of time to cause the formation of a hydroxyapatite or other calcium phosphate mineral layer on the nail surface.
    Type: Grant
    Filed: January 19, 2000
    Date of Patent: February 11, 2003
    Assignee: USBiomaterials Corporation
    Inventors: Guy LaTorre, David C. Greenspan, Alice D. Greenspan
  • Patent number: 6495168
    Abstract: This invention relates, generally, to nutritional supplements which contain bioactive glass. These supplements are useful in both veterinary and human contexts. The compositions of the subject invention can be used to achieve a number of advantageous results including: enhancing the growth rates of young animals, osteogenic stimulation, strengthening the skeletal structure, and treating osteoporosis.
    Type: Grant
    Filed: March 26, 2001
    Date of Patent: December 17, 2002
    Assignees: USTherapeutics, LLC, USBiomaterials Corporation
    Inventors: Jon K. West, David Greenspan, James L. Meyers
  • Patent number: 6428800
    Abstract: A method for treating wounds including contacting a wound with an effective wound healing amount of bioactive glass and topical antibiotic and composition for the accelerated healing of wounds and burns including particulates of bioactive glass and at least one topical antibiotic.
    Type: Grant
    Filed: October 1, 1998
    Date of Patent: August 6, 2002
    Assignee: USBiomaterials Corporation
    Inventors: David C. Greenspan, Jon K. West
  • Patent number: 6423343
    Abstract: This invention relates to a method for treating inflammatory symptoms such as burning, redness, itching, swelling and pain which accompany skin disorders other than wounds of the skin. The method comprising topical application of a topical medicinal composition comprising a non-interlinked, particulate bioactive glass mixed with a topical medicinal carrier to the site of the skin disorder.
    Type: Grant
    Filed: January 23, 1998
    Date of Patent: July 23, 2002
    Assignee: USBiomaterials Corporation
    Inventors: Sean Lee, James L. Meyers
  • Patent number: 6344496
    Abstract: Biodegradable polymeric therapeutic substantially nonporous implant materials incorporating bioactive ceramics such as Bioglass® ceramic are provided. These implants provide increased mechanical properties and pH control, enabling the use of these materials to design porous and nonporous therapeutic implants used as cell scaffolds for healing of tissue defects or fixation devices, having desired degradation times, mechanical properties, elasticity and biocompatibility.
    Type: Grant
    Filed: October 5, 1999
    Date of Patent: February 5, 2002
    Assignees: OsteoBiologics, Inc., USBiomaterials Corporation
    Inventors: Gabriele Niederauer, Kristine Kieswetter, Neil C. Leatherbury, David C. Greenspan
  • Patent number: 6306925
    Abstract: The invention described herein is a bioactive composite material comprising thin layers of bioactive glass reinforced with thin ductile metallic layers, and the use of this material in bone replacement procedures.
    Type: Grant
    Filed: December 18, 1998
    Date of Patent: October 23, 2001
    Assignee: Usbiomaterials Corporation
    Inventors: Daniel Clupper, John J. Mechlosky, Jr., Zheng Chen
  • Patent number: 5977204
    Abstract: Biodegradable polymeric therapeutic implant materials incorporating bioactive ceramics such as Bioglass.RTM. ceramic are provided. These implants provide increased mechanical properties and pH control, enabling the use of these materials to design porous and nonporous therapeutic implants used as cell scaffolds for healing of tissue defects or fixation devices, having desired degradation times, mechanical properties, elasticity and biocompatibility.
    Type: Grant
    Filed: April 11, 1997
    Date of Patent: November 2, 1999
    Assignees: OsteoBiologics, Inc., USBiomaterials Corporation
    Inventors: Barbara D. Boyan, Gabriele Niederauer, Kristine Kieswetter, Neil C. Leatherbury, David C. Greenspan
  • Patent number: 5735942
    Abstract: A novel silica based bioactive glass composition that can be used in conjunction with a delivery agent such as a toothpaste, gel saliva, etc. having a particle size range <90 .mu.m which will form a rapid and continuous reaction with body fluids due to the immediate and long term ionic release of Ca and P from the core silica particles, to produce a stable crystalline hydroxy carbonate apatite layer deposited onto and into the dentin tubules for the immediate and long term reduction of dentin hypersensitivity.
    Type: Grant
    Filed: July 16, 1997
    Date of Patent: April 7, 1998
    Assignees: USBiomaterials Corporation, University of Maryland
    Inventors: Leonard J. Litkowski, Gary D. Hack, David C. Greenspan