Patents Assigned to USSR Cardiology Research Centre
  • Negatively charged specific affinity reagents
    Patent number: 5223242
    Abstract: An in vivo imaging or therapeutic method including administering to a mammal a specific affinity reagent including a physiologically compatible polymer bonded to one or more specific affinity molecules capable of selectively binding to a predetermined substance or class of cells, and one or more reporter groups capable of providing detectable contrast between the predetermined substance or class of cells and cells or substances of the mammal to which the specific affinity reagent does not bind, or of killing cells of the predetermined class.
    Type: Grant
    Filed: February 21, 1992
    Date of Patent: June 29, 1993
    Assignees: The General Hospital Corporation, USSR Cardiology Research Centre
    Inventors: Ban A. Khaw, Vladimir Torchilin, Alexander L. Klibanov