Patents Assigned to USTAV MOLEKULARNI GENETIKY AV CR, V.V.I.
  • Phospholipid derivatives and their use as medicaments
    Patent number: 11414443
    Abstract: The present invention relates to 1-acyl-lysophosphatidyl derivatives of general formula I; in which R is C4 to C30 aliphatic hydrocarbyl chain, R1 is selected from H or C1 to C10 alkyl, preferably C1 to C6 alkyl, R2 is selected from H, C10 to C30 acyl or C1 to C10 alkyl, preferably C1 to C6 alkyl, and R3, when present, is selected from H or C1 to C10 alkyl, preferably C1 to C6 alkyl. These derivatives are intended for the treatment of cancer, in particular melanoma, hepatocarcinoma or GIT carcinomas.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: August 16, 2022
    Assignees: USTAV MOLEKULARNI GENETIKY AV CR, V.V.I., SMART BRAIN S.R.O.
    Inventors: Michal Dvorak, Marta Dvorakova, Vit Karafiat, Jan Stursa, Lukas Werner, Lucie Janeckova