Abstract: In a microprobe system for medical applications particularly for use in neurophysiology and neurosurgery a target determining arrangement is provided which can be mounted on a patients head by means of an adjustable mounting device. An adapter is removably attached to the mounting device and carries a manipulator with a removable probe unit that can be moved by a drive unit which is electrically controllable according to spatial coordinates (x,y,z—respectively, R,&phgr;). The probe unit includes a guide tube for receiving an exchangeable microfiber electrode, which includes sensor areas at its pointed tip for the recording of brain activity signals. The signals can be stored with a PC-interface in a data acquisition unit, which is in communication with an output unit. The manipulator includes a microfiber electrode control unit, for example, an XYZ-slide with locking means as well as a base body for the attachment of the probe unit to the mounting device in a predetermined orientation.

Abstract: A microprobe for electrophysiological application, a microtube, fiber or wire probe is supported on a fixture within a tubular elastic support hose end has one end together with one end of the probe mounted on a clamping structure which is movably disposed on the fixture while the other end of the probe extends through a capillary guide tube from which its tip projects and the other end of the hose is mounted on the fixture and the hose maintained in a stretched state to engage the probe and provide radial support and a microdrive is connected to the clamping structure for axially moving the probe together with the one end of the hose and an apparatus including a plurality of independently movable probes.