Abstract: Composition and electrode for phosphate sensing. In one embodiment, the composition includes a first component, a second component, and a third component. The first component is selected from a group consisting of cobalt oxide nanoparticles, tin (IV) chloride, diphenyl tin dichloride, and ammonium molybdate. The second component includes graphene oxide or reduced graphene oxide. The third component includes pyrrole or polypyrrole.

Abstract: A cured concrete and stone bore working tool and method of forming radially oriented discontinuities in a bore or perforation formed in a cured concrete or stone material such that, after use or application of the tool, the perforation formed in the cured concrete or stone material is configured to provide a non-planar adhesive interface and isolate a properly sized anchor or fastener from direct contact with the wall of the bore. Fasteners or anchors adhesively secured in bores previously treated with the bore treating tool exhibit improved creep failure performance as compared to fasteners adhesively secured to untreated bores.

Abstract: A medical tubing organizer includes a base defining a longitudinal direction, a lateral direction being defined as substantially orthogonal to the longitudinal direction, and a vertical direction being defined as substantially orthogonal to the longitudinal and lateral directions. A tube retainer is positioned on a top of the base and configured to receive a medical tube that extends along the lateral direction. The tube retainer is further configured to adjust between a free flow state and a retention state, wherein, in the free flow state, the tube retainer is configured to enable movement of the medical tube in the lateral direction and resist movement in the longitudinal direction, and in the retention state, the tube retainer is configured to resist movement in the lateral, longitudinal, and vertical directions. A connector is positioned on the base for selectively coupling the medical tubing organizer to a structure.

Abstract: Provided herein are alpha5-containing GABAA receptor agonists and pharmaceutical compositions and methods of treatment of cognitive and mood symptoms in neurodegenerative and neuropsychiatric disorders using them.

Abstract: Disclosed herein are extraction chromatographic supports comprising a porous support, an inert filler, and metal ion binding extractant that may be used for chromatographic separation of metal ions. Also disclosed herein are methods for preparing and using the extraction chromatographic supports.

Abstract: The present disclosure concerns methods of using novel bacterial strains of 0617-T307, 0917-T305, 0917-T306, 0917-T307, 0118-T319, 0318-T327, and 0418-T328, the cell broth and novel metabolites produced from the bacterial strains, that can inhibit the growth of a variety of microbial species for a variety of crops.

Abstract: The present disclosure concerns methods of using novel bacterial strains of 0617-T307, 0917-T305, 0917-T306, 0917-T307, 0118-T319, 0318-T327, and 0418-T328, the cell broth and novel metabolites produced from the bacterial strains, that can inhibit the growth of a variety of fish pathogens.

Abstract: The present disclosure concerns methods of using novel bacterial strains of 0617-T307, 0917-T305, 0917-T306, 0917-T307, 0118-T319, 0318-T327, and 0418-T328, the cell broth and novel metabolites produced from the bacterial strains, that can inhibit the growth of a variety of microbial species for a variety of crops.

Abstract: A dust collection assembly for a computer numerical control (CNC) cutting machine includes an adapter configured to couple to an arm of the CNC cutting machine and a head telescopically coupled to the adapter by a plurality of nested members. The CNC cutting machine includes the arm supporting a spindle and a tool holder coupled for co-rotation with the spindle. Each of the plurality of nested members are collapsible relative to each other. The head is movable between an extended position in which the nested members are configured to surround the tool holder and a tool bit, and a retracted position in which at least some of the nested members are telescopically received in the adapter. The head defines an inlet fluidly connected to the plurality of nested members when the head is at least in the extended position. The inlet is configured to fluidly connect to a vacuum.

Abstract: Substituted benzo[f]imidazo[1,5-?][1,4]diazepines of formula (I?) target alpha-4 and alpha-5 GABAA receptors for use in the treatment of airway hyperresponsiveness and inflammation in asthma. Compounds selectively partition to the peripheral compartment and have reduced CNS effects.

Abstract: A coating composition comprises a functionalized epoxy resin and a fluoroalkyl-modified particle, such as activated carbon or silica. The functionalized epoxy resin is a ternary polymer composition comprising one or more epoxy resin moieties linked to a polyethylene backbone through an oxygen atom, fluoroalkyl(poly)propionyl groups being grafted to the polyethylene backbone. The coating compositions have superhydrophobic properties useful for self-cleaning surfaces and bubble release from sensors.

Abstract: Provided herein are novel pyrazoloquinolinone compounds and method of using such compounds to treat disorders such as neuropsychiatric disorders with sensorimotor gating deficits, such as schizophrenia, tic disorders, attention deficit hyperactivity disorder, obsessive compulsive disorder, panic disorder, Huntington's disease and nocturnal enuresis; depression; temporomandibular myofascial pain; disorders of trigeminal nerve, such as trigeminal neuralgia and trigeminal neuropathy; migraine; and tinnitus.

Abstract: Sensors for detecting and distinguishing metals in a sample comprise phenol group-containing azo dyes, the phenol group having one hydroxy involved in reversible metal ion binding and a second hydroxy alkylated to an optically transparent substrate. The sensors have utility for detecting chromium, calcium, magnesium, copper, mercury, nickel, zinc, cobalt, manganese, cadmium, lead, tin, aluminum, potassium, sodium, or arsenic ions in a sample.

Abstract: Disclosed herein are novel HDAC inhibitors. The HDAC inhibitors may be used in methods of treating cancer. The HDAC inhibitors may be used in methods of treating a neurological disorder.

Abstract: A panel assembly for a building includes a panel configured to extend between a first surface and a second surface. The panel is movable along a predetermined path relative to the first surface and the second surface. A first pin and a second pin are coupled to the panel. A first bottom face plate is positioned on a first side and defines a first slot. A second bottom face plate is positioned on a second side and defines a second slot. A first top face plate is positioned on the first side and defines a third slot. A second top face plate is positioned on the second side and defines a fourth slot. The first pin is movable in the first slot and the second slot, and the second pin is movable in the third slot and the fourth slot for guiding movement of the panel along the predetermined path.

Abstract: The present invention relates to methods of using cell-free DNA analysis for guiding treatment of advanced prostate cancer. In particular, liquid biopsies are collected from urine and/or plasma of patients for measuring copy number variation in cell-free DNA associated with metastatic prostate cancer. In particular, urine genomic abnormality (UGA) and plasma genomic abnormality (PGA) values are contemplated for use in predicting treatment responses in advanced prostate cancer patients and for use in making decisions related to androgen deprivation therapy (ADT) treatment outcomes in hormone sensitive stage and for starting or changing chemotherapy treatments in castrate resistant advanced cancer stage.

Abstract: Provided herein are alpha5-containing GABAA receptor agonists and pharmaceutical compositions and methods of treatment of cognitive and mood symptoms in neurodegenerative and neuropsychiatric disorders using them.

Abstract: This invention relates to a system that adaptively compensates for subject motion in real-time in an imaging system. An object orientation marker (30), preferably a retro-grate reflector (RGR), is placed on the head or other body organ of interest of a patient (P) during a scan, such as an MRI scan. The marker (30) makes it possible to measure the six degrees of freedom (x, y, and z-translations, and pitch, yaw, and roll), or “pose”, required to track motion of the organ of interest. A detector, preferably a camera (40), observes the marker (30) and continuously extracts its pose. The pose from the camera (40) is sent to the scanner (120) via an RGR processing computer (50) and a scanner control and processing computer (100), allowing for continuous correction of scan planes and position (in real-time) for motion of the patient (P).

Abstract: Provided herein are novel pyrazolo-quinolinone compounds and method of using such compounds to treat disorders such as neuropsychiatric disorders with sensorimotor gating deficits, such as schizophrenia, tic disorders, attention deficit hyperactivity disorder, obsessive compulsive disorder, panic disorder, Huntington's disease and nocturnal enuresis; depression; temporomandibular myofascial pain; disorders of trigeminal nerve, such as trigeminal neuralgia and trigeminal neuropathy; migraine; and tinnitus.

Abstract: The present disclosure provides enhanced zeolites and methods of making and using same.