Abstract: A method is provided for preventing and/or treating heart failure in a subject in need thereof by administering to the subject a therapeutically effective amount of polydextrose. The method may also include the use of polydextrose for preventing cardiac remodeling and/or ventricle dilatation and/or for preventing systolic dysfunction, as well as preventing an increase in bacterial translocation to heart tissue in a subject who suffered from a myocardial infarction.
Type:
Grant
Filed:
January 5, 2021
Date of Patent:
June 27, 2023
Assignees:
VAIOMER, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
Inventors:
Christophe Heymes, Rémy Burcelin, Benjamin Lelouvier, Jacques Amar
Abstract: The present invention concerns methods, in particular in vitro methods, for diagnosing liver fibrosis in a subject suffering from obesity, or for selecting a subject suffering from obesity for liver biopsy or for treatment. The present invention also pertains to methods for screening a probiotic, a prebiotic, a chemical compound or a biological compound suitable for preventing and/or treating liver fibrosis.
Type:
Grant
Filed:
April 23, 2015
Date of Patent:
July 2, 2019
Assignees:
VAIOMER, UNIVERSITÀ DEGLI STUDI DI ROMA TOR VERGATA, FUNDACIÓ INSTITUT D'INVESTIGACIÓ BIOMÈDICA DE GIRONA DR. JOSEP TRUETA
Inventors:
Michael Courtney, Benjamin Lelouvier, Massimo Federici, Jose Manuel Fernandez-Real, Sandrine Païssé
Abstract: The present invention concerns a factor Xa inhibitor for use as a medicament in a method for regulating glycemia in a subject, in particular for use for preventing and/or treating hyperglycemia, impaired glucose tolerance, impaired fasting glucose, insulin resistance and/or diabetes.
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