Patents Assigned to Valeas S.p.A.
  • Rectal flunisolide compositions for treating inflammatory intestinal disorders
    Patent number: 5721228
    Abstract: Topical rectal therapeutic composition containing, as the active ingredient, flunisolide and/or one or more ester derivatives of same, in combination with suitable excipients and/or diluents, for the treatment of inflammatory intestinal disorders.
    Type: Grant
    Filed: May 17, 1995
    Date of Patent: February 24, 1998
    Assignee: Valeas S.p.A. Industria Chimica E Farmaceutica
    Inventors: Virgilio Bernareggi, Maurizio Fano, Alessandro Gagnoni
  • Tetrazole amide derivatives of heterocyclic alkenyl acid and their use as antiallergic substances
    Patent number: 5039684
    Abstract: Tetrazole amide derivatives of heterocyclic alkenyl acids, of general formula ##STR1## in which Y=NH, O or S when m=1;Y=N when m=2;m=1 or 2;l=0 or 4;R=H, C.sub.1-4 alkyl, Cl, Br, CF.sub.3, CH.sub.2 OCOCH.sub.3, or OCH.sub.2 -Ph;R.sub.1 =H, alkaline metal or alkaline earth metal, the double bond of the alkenyl chain being of trans or cis configuration and the possible benzene ring being unsubstituted or substituted.Such derivatives possess high antiallergic activity.
    Type: Grant
    Filed: February 23, 1990
    Date of Patent: August 13, 1991
    Assignee: Valeas S. p. A.
    Inventors: Virgilio Bernareggi, Fausto Bonifacio, Maurizio Fano, Luciano Trabella, Giandomenico Battigelli, Davide Montagna
  • Spasmolytic endo-8,8-dialkyl-8-azoniabicyclo (3.2.1) octane-6,7-exo-epoxy-3-alkyl-carboxylate salts
    Patent number: 4558054
    Abstract: The invention relates to new products, namely endo-8,8-dialkyl-8-azoniabicyclo [3.2.1] octane-6,7-exo-epoxy-3-alkylcarboxylates, of formula: ##STR1## in which R.sub.1 and R.sub.2, which can be the same or different, are linear or branched alkyl radicals of 1-5 C atoms or cycloalkyl radicals of 3-6 C atoms;R.sub.3 and R.sub.4, which can be the same or different, are alkyl radicals of 1-6 C atoms;X.sup.- is a halide ion.The new compounds are powerful spasmolytics.
    Type: Grant
    Filed: July 6, 1984
    Date of Patent: December 10, 1985
    Assignee: Valeas S.p.A.
    Inventors: Virgilio Bernareggi, Fausto Bonifacio, Roberto Margutti, Maurizio Fano
  • Salts of endo-8-methyl-8-syn-alkyl-8-azoniabicyclo-[3.2.1]-octane-3-alkylcarboxyl ates, and therapeutic compositions containing them
    Patent number: 4411902
    Abstract: The invention relates to new salts of endo-8-methyl-8-syn-alkyl-8-azoniabicyclo-[3.2.1]-octane-3-alkylcarboxylat es, of formula: ##STR1## in which R.sub.1 is a linear or branched alkyl radical of 2-5 C atoms, a cycloalkyl radical of 3-6 C atoms, or a phenyl-alkyl radical, R.sub.3 and R.sub.4, which can be the same or different, are alkyl radicals of 1-6 C atoms, X is a halide ion.The new compounds are potent spasmolytics.
    Type: Grant
    Filed: June 3, 1981
    Date of Patent: October 25, 1983
    Assignee: Valeas S.p.A.
    Inventors: Virgilio Bernareggi, Roberto Margutti, Fausto Bonifacio, Maurizio Fano