Patents Assigned to Valeas S.p.A.
  • Rectal flunisolide compositions for treating inflammatory intestinal disorders
    Patent number: 5721228
    Abstract: Topical rectal therapeutic composition containing, as the active ingredient, flunisolide and/or one or more ester derivatives of same, in combination with suitable excipients and/or diluents, for the treatment of inflammatory intestinal disorders.
    Type: Grant
    Filed: May 17, 1995
    Date of Patent: February 24, 1998
    Assignee: Valeas S.p.A. Industria Chimica E Farmaceutica
    Inventors: Virgilio Bernareggi, Maurizio Fano, Alessandro Gagnoni
  • Spasmolytic endo-8,8-dialkyl-8-azoniabicyclo (3.2.1) octane-6,7-exo-epoxy-3-alkyl-carboxylate salts
    Patent number: 4558054
    Abstract: The invention relates to new products, namely endo-8,8-dialkyl-8-azoniabicyclo [3.2.1] octane-6,7-exo-epoxy-3-alkylcarboxylates, of formula: ##STR1## in which R.sub.1 and R.sub.2, which can be the same or different, are linear or branched alkyl radicals of 1-5 C atoms or cycloalkyl radicals of 3-6 C atoms;R.sub.3 and R.sub.4, which can be the same or different, are alkyl radicals of 1-6 C atoms;X.sup.- is a halide ion.The new compounds are powerful spasmolytics.
    Type: Grant
    Filed: July 6, 1984
    Date of Patent: December 10, 1985
    Assignee: Valeas S.p.A.
    Inventors: Virgilio Bernareggi, Fausto Bonifacio, Roberto Margutti, Maurizio Fano
  • Salts of endo-8-methyl-8-syn-alkyl-8-azoniabicyclo-[3.2.1]-octane-3-alkylcarboxyl ates, and therapeutic compositions containing them
    Patent number: 4411902
    Abstract: The invention relates to new salts of endo-8-methyl-8-syn-alkyl-8-azoniabicyclo-[3.2.1]-octane-3-alkylcarboxylat es, of formula: ##STR1## in which R.sub.1 is a linear or branched alkyl radical of 2-5 C atoms, a cycloalkyl radical of 3-6 C atoms, or a phenyl-alkyl radical, R.sub.3 and R.sub.4, which can be the same or different, are alkyl radicals of 1-6 C atoms, X is a halide ion.The new compounds are potent spasmolytics.
    Type: Grant
    Filed: June 3, 1981
    Date of Patent: October 25, 1983
    Assignee: Valeas S.p.A.
    Inventors: Virgilio Bernareggi, Roberto Margutti, Fausto Bonifacio, Maurizio Fano