Patents Assigned to Valeritas, Inc.
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Publication number: 20180028743Abstract: A fluid delivery device for administering a first medicament and a second medicament includes a first fluid reservoir configured to contain the first medicament and a second fluid reservoir configured to contain the second medicament. The fluid delivery device may include one or more basal drive mechanisms to provide a basal delivery of one or more of the first and second medicaments. The fluid delivery device may further include one or more bolus drive mechanisms to provide a bolus delivery of one or more of the first and second medicaments.Type: ApplicationFiled: May 17, 2017Publication date: February 1, 2018Applicant: Valeritas, Inc.Inventors: Robert R. GONNELLI, Steven F. LEVESQUE, Ronald V. NARDI
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Publication number: 20170361016Abstract: A fluid delivery device includes an automatic needle retraction mechanism configured to automatically retract a delivery end of a needle into a housing. In one embodiment, the needle assembly is configured to automatically withdraw the delivery end of the needle into the housing upon an actuator moving from the first position to the second position. In one embodiment, the needle assembly is configured to automatically withdraw the delivery end of the needle into the housing upon decoupling a bottom surface of the housing from a skin surface.Type: ApplicationFiled: September 6, 2017Publication date: December 21, 2017Applicant: Valeritas, Inc.Inventors: Steven F. Levesque, Geoffrey H. Jenkins, Robert L. Standley, Matthew P. Johnson, Daniel A. Dube, Jr.
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Patent number: 9833383Abstract: A fluid transfer device for transferring fluid between a supply reservoir and a fill reservoir includes a metering reservoir and a manifold that forms at least part of a first channel that is fluidly connected with the metering reservoir. The first channel comprises a first cannula extending from the manifold. The manifold forms at least part of a second channel fluidly connected with the metering reservoir. The second channel comprises a second cannula extending from the manifold. A third channel extends through the manifold and comprises a third cannula having a first end proximate a distal end of the first cannula and a second end proximate a distal end of the second cannula. A first check valve is disposed within the first channel and a second check valve is disposed within the second channel.Type: GrantFiled: May 26, 2016Date of Patent: December 5, 2017Assignee: VALERITAS, INC.Inventors: Robert R. Gonnelli, Robert L. Standley, Steven F. Levesque
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Patent number: 9814831Abstract: A fluid delivery device comprises a fluid reservoir for containing medicament. The fluid reservoir is sealed proximate one end with a sliding seal piston. A delivery path is configured to fluidly couple the fluid reservoir and a patient wearing the fluid delivery device. A basal engine mechanism is configured to directly or indirectly move the sliding seal piston in the fluid reservoir at a controlled basal rate. A bolus mechanism configured to move the basal engine relative to the fluid reservoir and directly or indirectly move the sliding seal piston in the fluid reservoir a discrete bolus amount at a time.Type: GrantFiled: January 28, 2015Date of Patent: November 14, 2017Assignee: VALERITAS, INC.Inventor: Robert R. Gonnelli
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Patent number: 9795735Abstract: A fluid delivery device includes an automatic needle retraction mechanism configured to automatically retract a delivery end of a needle into a housing. In one embodiment, the needle assembly is configured to automatically withdraw the delivery end of the needle into the housing upon an actuator moving from the first position to the second position. In one embodiment, the needle assembly is configured to automatically withdraw the delivery end of the needle into the housing upon decoupling a bottom surface of the housing from a skin surface.Type: GrantFiled: April 23, 2014Date of Patent: October 24, 2017Assignee: VALERITAS, INC.Inventors: Steven F. Levesque, Geoffrey H. Jenkins, Robert L. Standley, Matthew P. Johnson, Daniel A. Dube, Jr.
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Publication number: 20170296741Abstract: A fluid delivery device comprises a drive unit including an actuator and one or more first features and a cartridge filled with a fluid prior to being inserted into the housing. The cartridge having a fluid reservoir sealed at one end by a movable piston and sealed at another end by a pierceable septum. The cartridge includes one or more second features that are configured to align and mate with the one or more first features allowing the cartridge to be inserted into the drive unit. The piston is moveable by the actuator once the cartridge is inserted into the drive unit.Type: ApplicationFiled: October 12, 2015Publication date: October 19, 2017Applicant: Valeritas, Inc.Inventor: Christopher C. Gregory
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Publication number: 20170189610Abstract: Fluid delivery and measurement systems and methods are disclosed.Type: ApplicationFiled: March 21, 2017Publication date: July 6, 2017Applicant: Valeritas, Inc.Inventors: Robert R. Gonnelli, Steven F. Levesque, David Lipson, Peter F. Marshall
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Patent number: 9687599Abstract: A fluid delivery device for administering a first medicament and a second medicament includes a first fluid reservoir configured to contain the first medicament and a second fluid reservoir configured to contain the second medicament. The fluid delivery device may include one or more basal drive mechanisms to provide a basal delivery of one or more of the first and second medicaments. The fluid delivery device may further include one or more bolus drive mechanisms to provide a bolus delivery of one or more of the first and second medicaments.Type: GrantFiled: July 28, 2014Date of Patent: June 27, 2017Assignee: VALERITAS, INC.Inventors: Robert R. Gonnelli, Steven F. Levesque, Ronald V. Nardi
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Patent number: 9636451Abstract: Fluid delivery and measurement systems and methods are disclosed.Type: GrantFiled: February 24, 2015Date of Patent: May 2, 2017Assignee: VALERITAS, INC.Inventors: Robert R. Gonnelli, Steven F. Levesque, David Lipson, Peter F. Marshall
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Publication number: 20170035966Abstract: A fluid delivery device comprises a hydraulic pump chamber having a hydraulic fluid. A fluid reservoir is coupled to the hydraulic pump chamber and is configured to contain a fluid deliverable to a patient. A first actuator is coupled to the hydraulic pump chamber and is configured to pressurize the hydraulic pump chamber and configured to transfer energy through the hydraulic pump chamber to the fluid reservoir. A second actuator is coupled to the hydraulic pump chamber and is configured to pressurize the hydraulic pump chamber and configured to transfer energy through the hydraulic pump chamber to the fluid reservoir.Type: ApplicationFiled: October 21, 2016Publication date: February 9, 2017Applicant: Valeritas, Inc.Inventors: Robert R. Gonnelli, Devin V. McAllister, Steven F. Levesque
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Patent number: 9561042Abstract: The invention provides for microneedle devices for delivering agents across biological barriers. The microneedles include agent reservoirs integrated into the bodies of the microneedles, themselves.Type: GrantFiled: November 12, 2009Date of Patent: February 7, 2017Assignee: Valeritas, Inc.Inventors: Devin V. McAllister, Ciro DiMeglio
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Publication number: 20170000942Abstract: A fluid delivery device comprises a fluid reservoir for containing medicament. The fluid reservoir is sealed proximate one end with a sliding seal piston. A delivery path is configured to fluidly couple the fluid reservoir and a patient wearing the fluid delivery device. A basal engine mechanism is configured to directly or indirectly move the sliding seal piston in the fluid reservoir at a controlled basal rate. A bolus mechanism configured to move the basal engine relative to the fluid reservoir and directly or indirectly move the sliding seal piston in the fluid reservoir a discrete bolus amount at a time.Type: ApplicationFiled: January 28, 2015Publication date: January 5, 2017Applicant: Valeritas, Inc.Inventor: Robert R. Gonnelli
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Patent number: 9511187Abstract: A fluid delivery device comprises a hydraulic pump chamber having a hydraulic fluid. A fluid reservoir is coupled to the hydraulic pump chamber and is configured to contain a fluid deliverable to a patient. A first actuator is coupled to the hydraulic pump chamber and is configured to pressurize the hydraulic pump chamber and configured to transfer energy through the hydraulic pump chamber to the fluid reservoir. A second actuator is coupled to the hydraulic pump chamber and is configured to pressurize the hydraulic pump chamber and configured to transfer energy through the hydraulic pump chamber to the fluid reservoir.Type: GrantFiled: July 27, 2015Date of Patent: December 6, 2016Assignee: VALERITAS, INC.Inventors: Robert R. Gonnelli, Devin V. McAllister, Steven F. Levesque
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Publication number: 20160262983Abstract: A fluid transfer device for transferring fluid between a supply reservoir and a fill reservoir includes a metering reservoir and a manifold that forms at least part of a first channel that is fluidly connected with the metering reservoir. The first channel comprises a first cannula extending from the manifold. The manifold forms at least part of a second channel fluidly connected with the metering reservoir. The second channel comprises a second cannula extending from the manifold. A third channel extends through the manifold and comprises a third cannula having a first end proximate a distal end of the first cannula and a second end proximate a distal end of the second cannula. A first check valve is disposed within the first channel and a second check valve is disposed within the second channel.Type: ApplicationFiled: May 26, 2016Publication date: September 15, 2016Applicant: Valeritas, Inc.Inventors: Robert R. Gonnelli, Robert L. Standley, Steven F. Levesque
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Patent number: 9415198Abstract: A method and apparatus for application of a microneedle patch to a skin surface of a patient includes use of an applicator. The applicator includes a housing, a slidably disposed applicator plate, and a compression spring. The applicator plate is moveable between a retracted position and a deployed position, and has an engaging surface suitable for mashing up against a microneedle patch and pressing it against a skin surface. A docking system transfers the microneedle patch from a support to the applicator without requiring a user to handle the microneedle patch directly. Once mounted in the applicator, the microneedle patch is deployed against a skin surface of a patient for delivery of a desired agent via a microneedle array contained on the patch.Type: GrantFiled: October 9, 2015Date of Patent: August 16, 2016Assignee: Valeritas, Inc.Inventor: Devin V. McAllister
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Patent number: 9376224Abstract: A fluid transfer device for transferring fluid between a supply reservoir and a fill reservoir includes a metering reservoir and a manifold that forms at least part of a first channel that is fluidly connected with the metering reservoir. The first channel comprises a first cannula extending from the manifold. The manifold forms at least part of a second channel fluidly connected with the metering reservoir. The second channel comprises a second cannula extending from the manifold. A third channel extends through the manifold and comprises a third cannula having a first end proximate a distal end of the first cannula and a second end proximate a distal end of the second cannula. A first check valve is disposed within the first channel and a second check valve is disposed within the second channel.Type: GrantFiled: January 16, 2014Date of Patent: June 28, 2016Assignee: VALERITAS, INC.Inventors: Robert R. Gonnelli, Robert L. Standley, Steven F. Levesque
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Publication number: 20160082182Abstract: A fluid delivery device comprises a housing having a bottom surface configured to be coupled to the skin surface. The fluid delivery device includes a cartridge prefilled with a fluid and configured to be inserted into the housing. The cartridge has a septum configured to be generally perpendicular to the bottom surface when the cartridge is inserted in the housing. The fluid delivery device includes a needle assembly that has a needle that includes a fluid coupling end and a delivery end. The fluid coupling end of the needle is fluidly disengaged from the cartridge in an initial position. The delivery end of the needle extends past the plane of the bottom surface and the fluid coupling end of the needle extends through the septum in a deployed position.Type: ApplicationFiled: May 30, 2014Publication date: March 24, 2016Applicant: VALERITAS, INC.Inventors: Christopher C. Gregory, Matthew P. Johnson, Roberl L. Standley
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Publication number: 20150328400Abstract: A fluid delivery device comprises a hydraulic pump chamber having a hydraulic fluid. A fluid reservoir is coupled to the hydraulic pump chamber and is configured to contain a fluid deliverable to a patient. A first actuator is coupled to the hydraulic pump chamber and is configured to pressurize the hydraulic pump chamber and configured to transfer energy through the hydraulic pump chamber to the fluid reservoir. A second actuator is coupled to the hydraulic pump chamber and is configured to pressurize the hydraulic pump chamber and configured to transfer energy through the hydraulic pump chamber to the fluid reservoir.Type: ApplicationFiled: July 27, 2015Publication date: November 19, 2015Applicant: VALERITAS, INC.Inventors: Robert R. Gonnelli, Devin V. McAllister, Steven F. Levesque
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Publication number: 20150314065Abstract: The invention provides various devices for delivering Glucagon-Like Peptide-1 (7-36), in various infusion patterns and rates, to optimally stimulate carbohydrate metabolism, to inhibit gastropancreatic secretion and gastric motility, and to treat various disease conditions (including diabete) as described in the instant specification. The devices and methods of the invention provide various ways to deliver doses (escalating, constant, on demand, etc.) of GLP-1 in response to different patient need.Type: ApplicationFiled: June 15, 2015Publication date: November 5, 2015Applicant: VALERITAS, INC.Inventor: Robert R. Gonnelli
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Publication number: 20150306306Abstract: A fluid delivery device comprises a housing having a fluid reservoir. A needle is in fluid communication with the fluid reservoir in an engaged position and out of fluid communication with the fluid reservoir in armed and storage positions. A proximal end of a biasing member is coupled to the housing and a distal end of the biasing member is configured to deliver a force to the fluid reservoir. A piston member extends through the biasing member and is coupled to the distal end of the biasing member. The piston member is fixed with respect to the housing in a locked position such that the biasing member does not deliver the force to the fluid reservoir and moveable with respect to the housing in a released position such that the biasing member delivers the force to the fluid reservoir. Transitioning the needle from the storage position to the armed position transitions the piston from the locked position to the released position.Type: ApplicationFiled: July 2, 2015Publication date: October 29, 2015Applicant: VALERITAS, INC.Inventors: Robert R. Gonnelli, Steven F. Levesque