Abstract: The present invention relates to a method of evaluating the efficiency of sterilization processes by measurement of degradation level of prion protein indicators. When exposed to sterilization conditions, prion indicators are degraded in a manner to proportionally indicate the level of degradation of prion proteins themselves on medical devices or other surfaces usable in surgery and health cares.

Abstract: There is provided a process for sterilizing a dielectric contaminated object having at least one hollow part. The process comprises (a) producing a plasma by submitting a gas or a mixture of gases to an electromagnetic field; (b) treating the exterior of the object by means of an after-glow of the plasma; and (c) treating the at least one hollow part of the object by means of a discharge of the plasma, the discharge being produced inside the at least one hollow part. Step (c) is carried out before or after step (b). This process is particularly useful for sterilizing various medical or dental instruments. There is also provided a device for carrying such a process.