Abstract: We describe methods and compositions for treating a patient suffering from a hyperproliferative disorder or photoageing. Our methods involve blocking the activity of a retinol binding protein receptor (RBPr) in cells of the patient, and/or administering to the patient an antagonist of a retinol binding protein receptor (RBPr) and/or lowering the endogenous level of retinoic acid (RA) in cells of said patient.
Type:
Grant
Filed:
February 27, 2002
Date of Patent:
November 1, 2011
Assignee:
Vampex Limited
Inventors:
Simon Ward, Claes Bavik, Michael Cork, Rachid Tazi-Aahnini