Patents Assigned to Variagenics, Inc., a Delaware corporation
  • Gene sequence variations with utility in determining the treatment of disease, in genes relating to drug processing
    Publication number: 20040171056
    Abstract: Methods for identifying and utilizing variances in genes relating to efficacy and safety of medical therapy and other aspects of medical therapy are described, including methods for selecting an effective treatment.
    Type: Application
    Filed: March 11, 2004
    Publication date: September 2, 2004
    Applicant: Variagenics, Inc., a Delaware corporation
    Inventor: Vincent P. Stanton
  • Methods for genetic analysis of DNA using biased amplification of polymorphic sites
    Publication number: 20030219769
    Abstract: Methods for determing genotypes and haplotypes of genes are described. Also described are single nucleotide polymorphisms and haplotypes in the ApoE gene and methods of using that information.
    Type: Application
    Filed: November 5, 2002
    Publication date: November 27, 2003
    Applicant: Variagenics, Inc. a Delaware corporation
    Inventors: Jeffrey Olson, Martin Zillmann, Vincent P. Stanton
  • Methods for targeting RNA molecules
    Publication number: 20030073123
    Abstract: Described are methods for identifying targets in RNA molecules based on differences in RNA secondary structure related to sequence variances between different allelic forms. Also described are methods for identifying or developing small molecules which can be used to modulate a target RNA by creation of protein-small-molecule-RNA complexes, as well as compositions which include such small molecules and methods of using those small molecules and compositions.
    Type: Application
    Filed: September 26, 2002
    Publication date: April 17, 2003
    Applicant: Variagenics, Inc., a Delaware corporation
    Inventors: Ling X. Shen, Gregory L. Verdine, James P. Basilion, Vincent P. Stanton
  • Inhibitors of alternative alleles of genes encoding products that mediate cell response to environmental changes
    Publication number: 20020127714
    Abstract: Disclosed are methods for the treatment of proliferative disorders using compounds and/or environmental conditions which result in a difference in sensitivity of targeted and non-targeted cells. Certain of the methods involve the identification and use of allele-specific inhibitors of conditionally essential genes.
    Type: Application
    Filed: February 14, 2001
    Publication date: September 12, 2002
    Applicant: Variagenics, Inc., a Delaware corporation
    Inventors: David E. Housman, Fred D. Ledley, Vincent P. Stanton