Abstract: Embodiments described herein provide for recommending radiotherapy treatment attributes. A machine learning model predicts the preference of a medical professional and provides relevant suggestions (or recommendations) of radiotherapy treatment attributes for various categories of radiotherapy treatment. Specifically, the machine learning model predicts field geometry attributes from various field geometry attribute options for various field geometry attribute categories. The machine learning model is conditioned on patient data such as medical images and patient information. The machine learning model is trained in response to cumulative reward information associated with a medical professional accepting the provided/displayed recommendations.

Abstract: An asymmetric dual-mode ionization chamber measurement system can include a first high-voltage plate, a second high-voltage plate and a readout plate. The first high-voltage plate can be disposed from the readout plate by a first active volume. The second high-voltage plate can be disposed from the readout plate by a second active volume. A high-voltage potential can be coupled to the first high-voltage plate during a first mode, and to the second high-voltage plate during a second mode. Ion pairs generated by a radiation stream passing through the first active volume during the first mode and the second active volume during the second mode can be measured at the readout plate to determine a radiation rate of the ionizing radiation. The asymmetric dual-mode ionization chamber measurement system can advantageously measure different radiation streams that have significantly different ranges of radiation rates flux.

Abstract: A dose rate-volume histogram can be generated for a target volume. The dose rate-volume histogram can be stored in computer system memory and used to generate a radiation treatment plan. The radiation treatment plan can be used as the basis for treating a patient using a radiation treatment system.

Abstract: Nominal values of parameters, and perturbations of the nominal values, that are associated with previously defined radiation treatment plans are accessed. For each treatment field of the treatment plans, a field-specific planning target volume (fsPTV) is determined based on those perturbations. At least one clinical target volume (CTV) and at least one organ-at-risk (OAR) volume are also delineated. Each OAR includes at least one sub-volume that is delineated based on spatial relationships between each OAR and the CTV and the fsPTV for each treatment field. Dose distributions for the sub-volumes are determined based on the nominal values and the perturbations. One or more dose prediction models are generated for each sub-volume. The dose prediction model(s) are trained using the dose distributions.

Abstract: A radiation therapy system includes an accelerator and beam transport system that generates a beam of particles. The accelerator and beam transport system guides the beam on a path and into a nozzle that is operable for aiming the beam toward an object. The nozzle includes a scanning magnet operable for steering the beam toward different locations within the object, and also includes a beam energy adjuster configured to adjust the beam by, for example, placing different thicknesses of material in the path of the beam to affect the energies of the particles in the beam.

Abstract: Embodiments of the present disclosure are directed to methods and computer systems for converting datasets into three-dimensional (“3D”) mesh surface visualization, displaying the mesh surface on a computer display, comparing two three-dimensional mesh surface structures by blending two primary different primary colors to create a secondary color, and computing the distance between two three-dimensional mesh surface structures converted from two closely-matched datasets. For qualitative analysis, the system includes a three-dimensional structure comparison control engine that is configured to convert dataset with three-dimensional structure into three-dimensional surfaces with mesh surface visualization. The control engine is also configured to assign color and translucency value to the three-dimensional surface for the user to do qualitative comparison analysis. For quantitative analysis, the control engine is configured to compute the distance field between two closely-matched datasets.

Abstract: Disclosed herein are radiotherapy systems and methods that can display a workflow-oriented graphical user interface(s). In an embodiment, a system comprises a radiotherapy machine comprising: a couch; and a gantry having a camera in communication with a server, wherein the server is configured to: present for display, in real time on a screen associated with the radiotherapy machine, images received from the camera, wherein when the gantry changes its orientation, the camera revises at least one of its orientations, such that images transmitted to the server maintain an original orientation.

Abstract: A remote diagnostic monitoring of operating states for physical components of a particle accelerator system includes generating, by at least one processor, a component hierarchy corresponding to a physical arrangement of one or more physical components of a particle emitting system and including corresponding operating indicators of operating states of the physical components, identifying, by the at least one processor, a faulted physical component among the physical components, identifying, by the at least one processor, one or more fault path components among the physical components, the fault path components corresponding to a portion of the physical arrangement associated with the faulted physical component, and modifying, by the at least one processor, the operating indicators of the fault path components to fault state indicators.

Abstract: An example method for a radiation therapy system that includes a movable couch to perform radiation therapy has been disclosed. One method includes based on the X-ray images of an anatomical region of the patient that includes a target volume, reconstructing a digital volume of the anatomical region and based on a user input indicating a location of a patient origin in the digital volume, determining one or more shift values for repositioning the patient origin at an isocenter of the radiation therapy system with respect to a coordinate system. The method also includes obtaining a treatment plan that is based on the location of the patient origin and is associated with the target volume, based on the treatment plan, repositioning the movable couch so that the patient origin is disposed at the isocenter, and while the patient origin is disposed at the isocenter, directing a treatment beam to the patient origin in accordance with the treatment plan associated with the target volume.

Abstract: A remote diagnostic monitoring and control of physical components of a particle accelerator system has a particle emitting system located at a first physical site and includes one or more particle emitting system components to operate the particle emitting system, a particle delivery system located at the first physical site and including one or more particle delivery system components to operate the particle delivery system, a particle system gateway located at the first physical site and operatively coupled to the particle emitting system components and the particle delivery system components by a first network interface, and a diagnostic monitoring system located at a second physical site remote from the first physical site, operatively coupled to the particle system gateway by a second network interface, and operable to monitor one or more first operating states corresponding to one or more of the particle emitting system components and one or more second operating states corresponding to one or more of t

Abstract: A remote diagnostic control of physical components of a particle accelerator system includes presenting, by at least one processor at a first physical location, a fault control interface including at least one control affordance corresponding to a physical component associated with a particle emitting system and a particle delivery system each located at a second physical location remote from the first physical location, and at least one arrangement presentation corresponding to the physical component and at least one physical device including the physical component, the arrangement presentation including a first operating state indicator associated with the physical component and a second operating state indicator associated with the physical device, and in response to activating the control affordance, generating a device command for transmission to the physical component to modify an operating state of the physical component at one or more of the particle emitting system and the particle delivery system, m

Abstract: A multileaf collimator includes a plurality of movable leaves for shaping a radiotherapy beam, wherein each leaf is independently movable in a same linear travel direction. Each leaf includes a linear array of magnets disposed on a measurement surface of the leaf and an array of magnetoresistive sensors that is disposed proximate the measurement surfaces of the leaves.

Abstract: Example methods and apparatuses of controlling a user interface with a plurality of input mechanisms are disclosed. One example method includes causing a first set of input mechanisms in the plurality of input mechanisms to be visually emphasized via a first visual technique while a second set of input mechanisms in the plurality of input mechanisms is not visually emphasized via the first visual technique, receiving a user input via an input mechanism that is included in the first set, based on the user input, determining a third set of input mechanisms in the plurality of input mechanisms and a fourth set of input mechanisms in the plurality of input mechanisms, and causing the third set of input mechanisms to be visually emphasized via the first visual technique while the fourth set of available input mechanisms is not visually emphasized via the first visual technique.

Abstract: A three-dimensional model for a patient fixation device that serves to immobilize at least a portion of a particular patient when capturing CT image information of that patient is accessed and then registered with the pixels that correspond to the patient fixation device in the CT image. The model can specify rules of movement for each of a plurality of structural elements that comprise the patient fixation device and that are capable of movement relative to one another. By one approach the aforementioned registration occurs on a part-by-part basis for each of the structural elements. Following registration, the CT image can be automatically segmented.

Abstract: An imager includes: an array of imager elements configured to generate image signals based on radiation received by the imager; and circuit configured to perform readout of image signals, wherein the circuit is configured to be radiation hard. An imager includes: an array of imager elements configured to generate image signals based on the radiation received by the imager; and readout and control circuit coupled to the array of imager elements, wherein the readout and control circuit is configured to perform signal readout in synchronization with an operation of a treatment beam source.

Abstract: Presented systems and methods facilitate efficient and effective monitoring of particle beams. In some embodiments, a radiation gun system comprises: a particle beam gun that generates a particle beam, and a gun control component that controls the gun particle beam generation characteristics, including particle beam fidelity characteristics. The particle beam characteristics can be compatible with FLASH radiation therapy. Resolution control of the particle beam generation can enable dose delivery at an intra-pulse level and micro-bunch level. The micro-bunch can include individual bunches per each 3 GHz RF cycle within the 5 to 15 ?sec pulse-width. The FLASH radiation therapy dose delivery can have a bunch level resolution of approximately 4.4×10{circumflex over (?)}?6cGy/bunch.

Abstract: Systems and methods for radiation treatment planning can include a computing system determining an estimate of a radiation dose distribution within an anatomical region of a patient, and determining a cost matrix representing an objective function, using the estimate of the radiation dose distribution. The computing system can project the cost matrix on each of a plurality of fluence planes. Each of the plurality of fluence planes can be associated with a corresponding gantry-couch orientation of a plurality of gantry-couch orientations of a medical linear accelerator. The computing system can determine, using projections of the cost matrix on each of the plurality of fluence planes, a sequence of gantry-couch orientations among the plurality of gantry-couch orientations representing a treatment path.

Abstract: Deep learning approaches automatically segment at least some breast tissue images while non-deep learning approaches automatically segment organs-at-risk. Both three-dimensional CT imaging information and two-dimensional orthogonal topogram imaging information can be used to determine virtual-skin volume. The foregoing imaging information can also serve to automatically determine a body outline for at least a portion of the patient. That body outline, along with the virtual-skin volume and registration information can serve as inputs to automatically calculate radiation treatment platform trajectories, collision detection information, and virtual dry run information of treatment delivery per the optimized radiation treatment plan.

Abstract: A method for implementing a radiation therapy knowledge exchange starts with searching a database of cases studies and selecting a case study. The selected case study is downloaded. The downloaded case study is applied to a medical case, wherein the downloaded case is applied using deformable image registration to deform reference images of the downloaded case to medical images of the medical case. After application of the downloaded case study, the medical case is uploaded to the network, wherein uploading the medical case allows at least the submitting clinician to download, review, and edit at least a portion of the medical case to create a reviewed medical case. Finally, the reviewed medical case is downloaded and applied to the medical case to create a final medical case.

Abstract: An example computer-implemented method for tuning a beam spot in a radiation therapy system based on radiation field measurements has been disclosed. The example method includes configuring an electron beam to generate a first beam spot on an electron-beam target of the radiation therapy system, determining a value for one or more radiation field quality metrics for a first radiation beam that originates from the first beam spot, and based on the value, determining whether the first radiation beam is outside a specified quality range.