Abstract: 8-Hydroxy-quinoline derivatives and 8-ethers, 8-esters, 8-carbonates, 8-acyloxymethyl, 8-phosphates, (phosphoryloxy)methyl, and 8-carbamates derivatives thereof are described that exhibit iron chelation, neuroprotective, neurorestorative, apoptotic and/or selective MAO-AB inhibitory activities.
Type:
Application
Filed:
August 12, 2011
Publication date:
December 12, 2013
Applicant:
VARINEL INC
Inventors:
Vincent R. Zurawski, David M. Stout, Theodore J. Nitz, Moussa B.H. Youdim, Orly Weinreb