Patents Assigned to Vasgene Therapeutics, Inc.
  • Polypeptide compounds for inhibiting angiogenesis and tumor growth
    Patent number: 9533026
    Abstract: In certain embodiments, this present invention provides polypeptide compositions, including compositions containing a modified polypeptide, and methods for inhibiting Ephrin B2 or EphB4 activity. In other embodiments, the present invention provides methods and compositions for treating cancer or for treating angiogenesis-associated diseases.
    Type: Grant
    Filed: May 6, 2013
    Date of Patent: January 3, 2017
    Assignee: VASGENE THERAPEUTICS, INC
    Inventors: Valery Krasnoperov, Nathalie Kertesz, Ramachandra Reddy, Parkash Gill, Sergey Zozulya
  • Cancer treatment using humanized antibodies that bind to EphB4
    Patent number: 8975377
    Abstract: In certain embodiments, this application provides humanized antibodies that bind to the EphB4 protein as well as uses of the antibodies for therapeutic purposes.
    Type: Grant
    Filed: August 11, 2008
    Date of Patent: March 10, 2015
    Assignee: Vasgene Therapeutics, Inc
    Inventors: Parkash Gill, Valery Krasnoperov, Simon William Keen, Timothy David Jones, Francis Joseph Carr
  • POLYPEPTIDE COMPOUNDS FOR INHIBITING ANGIOGENESIS AND TUMOR GROWTH
    Publication number: 20140107030
    Abstract: In certain embodiments, this present invention provides polypeptide compositions, including compositions containing a modified polypeptide, and methods for inhibiting Ephrin B2 or EphB4 activity. In other embodiments, the present invention provides methods and compositions for treating cancer or for treating angiogenesis-associated diseases.
    Type: Application
    Filed: May 6, 2013
    Publication date: April 17, 2014
    Applicant: VasGene Therapeutics, Inc.
    Inventors: Valery Krasnoperov, Nathalie Kertesz, Ramachandra Reddy, Parkash Gill, Sergey Zozulya
  • POLYPEPTIDE COMPOUNDS FOR INHIBITING ANGIOGENESIS AND TUMOR GROWTH
    Publication number: 20130344075
    Abstract: In certain embodiments, this present invention provides polypeptide compositions (e.g., antibodies and antigen binding portions thereof that bind to EphB4), and methods for inhibiting EphB4 activity. In other embodiments, the present invention provides methods and compositions for treating cancer or for treating angiogenesis-associated diseases.
    Type: Application
    Filed: June 6, 2011
    Publication date: December 26, 2013
    Applicant: VASGENE THERAPEUTICS, INC.
    Inventors: Valery Krasnoperov, Nathalie Kertesz, Ramachandra Reddy, Parkash Gill, Sergey Zozulya
  • NON-IMMUNOGLOBULIN ANTIGEN BINDING SCAFFOLDS FOR INHIBITING ANGIOGENESIS AND TUMOR GROWTH
    Publication number: 20120294875
    Abstract: In certain embodiments, this present invention provides polypeptide or nucleotide non-immunoglobulin antigen binding scaffold compositions, and methods for inhibiting Ephrin B2 or EphB4 activity. In other embodiments, the present invention provides methods and compositions for treating cancer or for treating angiogenesis-associated diseases.
    Type: Application
    Filed: April 4, 2012
    Publication date: November 22, 2012
    Applicant: VASGENE THERAPEUTICS, INC.
    Inventor: Parkash Gill
  • POLYPEPTIDE COMPOUNDS FOR INHIBITING ANGIOGENESIS AND TUMOR GROWTH
    Publication number: 20120277162
    Abstract: In certain embodiments, this present invention provides polypeptide compositions, including compositions containing a modified polypeptide, and methods for inhibiting Ephrin B2 or EphB4 activity. In other embodiments, the present invention provides methods and compositions for treating cancer or for treating angiogenesis-associated diseases.
    Type: Application
    Filed: March 15, 2012
    Publication date: November 1, 2012
    Applicant: VASGENE THERAPEUTICS, INC.
    Inventors: Valery Krasnoperov, Nathalie Kertesz, Ramachandra Reddy, Parkash Gill, Sergey Zozulya
  • Polypeptide compounds for inhibiting angiogenesis and tumor growth
    Patent number: 8273858
    Abstract: In certain embodiments, this present invention provides polypeptide compositions, and methods for inhibiting Ephrin B2 or EphB4 activity. In other embodiments, the present invention provides methods and compositions for treating cancer or for treating angiogenesis-associated diseases.
    Type: Grant
    Filed: June 2, 2008
    Date of Patent: September 25, 2012
    Assignee: VasGene Therapeutics, Inc.
    Inventors: Valery Krasnoperov, Nathalie Kertesz, Ramachandra Reddy, Parkash Gill, Sergey Zozulya
  • Polypeptide compounds for inhibiting angiogenesis and tumor growth
    Patent number: 8063183
    Abstract: In certain embodiments, this present invention provides polypeptide compositions, and methods for inhibiting Ephrin B2 or EphB4 activity. In other embodiments, the present invention provides methods and compositions for treating cancer or for treating angiogenesis-associated diseases.
    Type: Grant
    Filed: October 6, 2006
    Date of Patent: November 22, 2011
    Assignee: VasGene Therapeutics, Inc.
    Inventors: Valery Krasnoperov, Nathalie Kertesz, Ramachandra Reddy, Parkash Gill, Sergey Zozulya
  • METHODS FOR USING AND IDENTIFYING MODULATORS OF DELTA-LIKE 4
    Publication number: 20110213127
    Abstract: In certain embodiments, this present invention provides antibodies that act as either agonists or antagonists of Delta-like 4 (Dll4) signaling.
    Type: Application
    Filed: February 4, 2011
    Publication date: September 1, 2011
    Applicant: VasGene Therapeutics, Inc.
    Inventors: Parkash Gill, Ren Liu, Valery Krasnoperov
  • Polypeptide compounds for inhibiting angiogenesis and tumor growth
    Patent number: 7977463
    Abstract: In certain embodiments, this present invention provides polypeptide compositions (e.g., antibodies and antigen binding portions thereof that bind to EphB4), and methods for inhibiting EphB4 activity. In other embodiments, the present invention provides methods and compositions for treating cancer or for treating angiogenesis-associated diseases.
    Type: Grant
    Filed: March 11, 2005
    Date of Patent: July 12, 2011
    Assignee: VasGene Therapeutics, Inc.
    Inventors: Valery Krasnoperov, Nathalie Kertesz, Ramachandra Reddy, Parkash Gill, Sergey Zozulya
  • POLYPEPTIDE COMPOUNDS FOR INHIBITING ANGIOGENESIS AND TUMOR GROWTH
    Publication number: 20110129482
    Abstract: In certain embodiments, this present invention provides polypeptide compositions, and methods for inhibiting Ephrin B2 or EphB4 activity. In other embodiments, the present invention provides methods and compositions for treating cancer or for treating angiogenesis-associated diseases.
    Type: Application
    Filed: November 23, 2010
    Publication date: June 2, 2011
    Applicant: VASGENE THERAPEUTICS, INC.
    Inventors: Valery Krasnoperov, Sergey Zozulya, Nathalie Kertesz, Ramachandra Reddy, Parkash Gill
  • NON-IMMUNOGLOBULIN ANTIGEN BINDING SCAFFOLDS FOR INHIBITING ANGIOGENESIS AND TUMOR GROWTH
    Publication number: 20110009323
    Abstract: In certain embodiments, this present invention provides polypeptide or nucleotide non-immunoglobulin antigen binding scaffold compositions, and methods for inhibiting Ephrin B2 or EphB4 activity. In other embodiments, the present invention provides methods and compositions for treating cancer or for treating angiogenesis-associated diseases.
    Type: Application
    Filed: June 12, 2008
    Publication date: January 13, 2011
    Applicant: VasGene Therapeutics, Inc.
    Inventor: Parkash Gill
  • Polypeptide compounds for inhibiting angiogenesis and tumor growth
    Patent number: 7862816
    Abstract: In certain embodiments, this present invention provides polypeptide compositions, and methods for inhibiting Ephrin B2 or EphB4 activity. In other embodiments, the present invention provides methods and compositions for treating cancer or for treating angiogenesis-associated diseases.
    Type: Grant
    Filed: March 12, 2004
    Date of Patent: January 4, 2011
    Assignee: Vasgene Therapeutics, Inc.
    Inventors: Valery Krasnoperov, Nathalie Kertesz, Ramachandra Reddy, Parkash Gill, Sergey Zozulya
  • METHODS AND COMPOSITONS FOR ANTISENSE VEGF OLIGONUCLEOTIDES
    Publication number: 20100330152
    Abstract: This invention relates to compositions and methods for inhibition of abnormal proliferation of cells or angiogenesis. More particularly this invention provides VEGF antisense oligonucleotides capable of inhibiting proliferation of cancer cells or angiogenesis or combinations thereof. also provided are screening and prognostic assays, as well kits comprising the VEGF antisense oligonucleotides.
    Type: Application
    Filed: October 5, 2009
    Publication date: December 30, 2010
    Applicant: VasGene Therapeutics, Inc.
    Inventors: Parkash Gill, Rizwan Masood, Sudhir Agrawal
  • Polypeptide compounds for inhibiting angiogenesis and tumor growth
    Publication number: 20100261653
    Abstract: In certain embodiments, this present invention provides polypeptide compositions, including compositions containing a modified polypeptide, and methods for inhibiting Ephrin B2 or EphB4 activity. In other embodiments, the present invention provides methods and compositions for treating cancer or for treating angiogenesis-associated diseases.
    Type: Application
    Filed: September 14, 2009
    Publication date: October 14, 2010
    Applicant: VasGene Therapeutics, Inc.
    Inventors: Valery Krasnoperov, Nathalie Kertesz, Ramachandra Reddy, Parkash Gill, Sergey Zozulya
  • NUCLEIC ACID COMPOUNDS FOR INHIBITING ANGIOGENESIS AND TUMOR GROWTH
    Publication number: 20100093831
    Abstract: In certain embodiments, this present disclosure provides nucleic acid compounds, compositions, and methods for inhibiting Ephrin B2 or EphB4 expression. In certain embodiments, the present disclosure provides methods and compositions for treating cancer or for treating angiogenesis-associated diseases.
    Type: Application
    Filed: September 1, 2009
    Publication date: April 15, 2010
    Applicant: VasGene Therapeutics, Inc.
    Inventors: Ramachandra Reddy, Parkash Gill
  • Nucleic acid compounds for inhibiting angiogenesis and tumor growth
    Patent number: 7585967
    Abstract: In certain embodiments, this present disclosure provides nucleic acid compounds, compositions, and methods for inhibiting Ephrin B2 or EphB4 expression. In certain embodiments, the present disclosure provides methods and compositions for treating cancer or for treating angiogenesis-associated diseases.
    Type: Grant
    Filed: March 12, 2004
    Date of Patent: September 8, 2009
    Assignee: VasGene Therapeutics, Inc.
    Inventors: Ramachandra Reddy, Parkash Gill
  • Cancer treatment using humanized antibodies that bind to EphB4
    Publication number: 20090196880
    Abstract: In certain embodiments, this application provides humanized antibodies that bind to the EphB4 protein as well as uses of the antibodies for therapeutic purposes.
    Type: Application
    Filed: August 11, 2008
    Publication date: August 6, 2009
    Applicant: Vasgene Therapeutics, Inc.
    Inventors: Parkash Gill, Valery Krasnoperov, Simon William Keen, Timothy David Jones, Francis Joseph Carr
  • Polypeptide compounds for inhibiting angiogenesis and tumor growth
    Publication number: 20090155251
    Abstract: In certain embodiments, this present invention provides polypeptide compositions, and methods for inhibiting Ephrin B2 or EphB4 activity. In other embodiments, the present invention provides methods and compositions for treating cancer or for treating angiogenesis-associated diseases.
    Type: Application
    Filed: June 2, 2008
    Publication date: June 18, 2009
    Applicant: VasGene Therapeutics, Inc.
    Inventors: Valery Krasnoperov, Sergey Zozulya, Nathalie Kertesz, Ramachandra Reddy, Parkash Gill
  • Methods for using and identifying modulators of Delta-like 4
    Publication number: 20090035308
    Abstract: In certain embodiments, this present invention provides methods of identifying and using agonists and antagonists of Delta-like 4 (Dll4) signaling.
    Type: Application
    Filed: December 20, 2007
    Publication date: February 5, 2009
    Applicant: VasGene Therapeutics, Inc.
    Inventors: Parkash Gill, Ren Liu, Valery Krasnoperov