Patents Assigned to Vasopharm Buitech GmbH
  • Use of tetrahydropteridine derivatives as no synthase inhibitors
    Patent number: 6858612
    Abstract: The present invention relates to the use of pteridine derivatives of the formula I in which X is O or NH and R4, for example, is hydrogen, phenyl or the radical R4a—CH2— and R4a, for example, is hydrogen, (C1-C4)-alkylmercapto, the radical —NR11R12 or the radical —OR13, and in which R1, R2, R3, R5, R6, R7, R11, R12 and R13 have the meanings given in claim 1, which are nitric oxide synthase inhibitors, for the treatment of diseases which are caused by an increased nitric oxide level.
    Type: Grant
    Filed: July 20, 1999
    Date of Patent: February 22, 2005
    Assignee: Vasopharm Buitech GmbH
    Inventors: Wolfgang Pfleiderer, Harald Schmidt, Rainer Henning