Abstract: Described herein are methods, formulations and kits for treating a patient with triple-negative breast cancer with nanoparticle complexes comprising a carrier protein (e.g., albumin), paclitaxel and a binding agent specific for a target antigen expressed by the cells (e.g., an anti-VEGF antibody).
Type:
Application
Filed:
September 5, 2017
Publication date:
September 9, 2021
Applicants:
Mayo Foundation for Medical Education and Research, Vavotar Life Sciences LLC
Inventors:
Gerald F. SWISS, Jesse CROWNE, Svetomir N. MARKVOIC, Wendy K. MEVALA
Abstract: Described herein are methods, formulations and kits for treating a patient with cancer with anti-VEGF antibodies and albumin-bound chemotherapeutic/anti-VEGF antibody nanoparticle complexes.
Type:
Grant
Filed:
April 6, 2016
Date of Patent:
February 18, 2020
Assignees:
Vavotar Life Sciences LLC, Mayo Foundation for Medical Education and Research
Inventors:
Gerald F. Swiss, Svetomir N. Markovic, Wendy K. Nevala