Abstract: Microneedle and microneedle devices including implantable tips (e.g., silk-based tips) for sustained dermal delivery of a coronavirus and/or influenza vaccine, kits, as well as methods of manufacturing and using the same are described herein. In other embodiments, compositions and methods for controlled- or sustained-administration of a coronavirus vaccine and/or an influenza vaccine to provide improved immunogenicity and/or broad-spectrum immunity to a subject are also described.
Type:
Application
Filed:
November 21, 2022
Publication date:
August 31, 2023
Applicant:
VAXESS TECHNOLOGIES, INC.
Inventors:
Michael A. Schrader, Kathryn M. Kosuda, Jonathan A. Kluge, Kimberly M. Cirelli, Emily L. Borkowski, Cassie L. Caudill, Matthew Dirckx, Nickolas W. Hartman, Livio Valenti
Abstract: The present disclosure relates to viral vaccine formulations with enhanced stability and methods of use thereof.
Type:
Application
Filed:
September 30, 2022
Publication date:
June 22, 2023
Applicant:
VAXESS TECHNOLOGIES, INC.
Inventors:
Kathryn M. Kosuda, David P. Miller, Nishant K. Jain, Carter R. Palmer, Jonathan A. Kluge, Jordan A. Stinson, Adrian Benton Li, Alexandra Krisiewicz
Abstract: Microneedle and microneedle devices including, e.g., silk fibroin-based microneedles tips for sustained dermal delivery of an anti-cancer agent and/or an immunomodulatory agent, as well as methods of manufacturing and using the same are described herein. In other embodiments, compositions and methods for burst-release or sustained-release administration of an anti-cancer agent and/or an immunomodulatory agent to provide an improved immune response to a cancer in a subject are described.
Type:
Application
Filed:
April 5, 2022
Publication date:
October 27, 2022
Applicant:
VAXESS TECHNOLOGIES, INC.
Inventors:
Kathryn M. Kosuda, Kimberly M. Cirelli, Alexander Beliveau, Archana V. Boopathy, Matthew Dirckx, Jonathan A. Kluge, Michael A. Schrader, Megan Eisele
Abstract: The present invention generally relates to the collection, storage, and stabilization of biological samples (e.g., bodily fluids, such as whole blood, blood serum, and blood plasma), and analytes thereof. More particularly, the present invention relates to polymer-based biological sample collection devices, and methods of making and using the same.
Type:
Application
Filed:
January 25, 2021
Publication date:
September 16, 2021
Applicant:
VAXESS TECHNOLOGIES, INC.
Inventors:
Jonathan A. Kluge, Alexander Beliveau, Adrian Benton Li, Matthew Dirckx, Michael A. Schrader, Kathryn M. Kosuda, Elizabeth Whitney Johansen
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